Transcriptome Profiling: Progress and Prospects is an ideal resource for anyone who wants to understand the latest topics, tools and techniques used in transcriptomics, transcriptome characterization, expression analysis of transcripts, transcriptome and gene regulation, transcriptome profiling and human health, medicinal plants transcriptomics, transcriptomics and genetic engineering, transcriptomics in agriculture, and phylotranscriptomics. It will help readers assess and interpret a large number of genes, often an entire genome, to obtain a global snapshot of the complete RNA component of a cell at a given time to distinguish between different cell types, different disease states, and different time points during development.
Transcriptome analysis has been a key area of biological inquiry for decades. The next-generation sequencing technologies have revolutionized transcriptomics by providing opportunities for multidimensional examinations of cellular transcriptomes in which high-throughput expression data are obtained at a single-base resolution. The transcriptome analysis has evolved from detection of single RNA molecules to large-scale gene expression profiling and genome annotation efforts.
- Presents recent development in the tools and techniques in transcriptomic characterization
- Integrates expression analysis of transcripts and gene regulation
- Includes the application of transcriptomics in human health, genetic engineering and agriculture
Recenzijos
*4 stars* "This multi-author, edited volume takes a largely experimental approach to describing recent progress in transcriptome profiling, looking at both recent applications and future prospects. More than 80 authors contributed to this volume and individual chapters take a research-oriented approach to the presentation of information. Several of the chapters could serve as a "how to" introduction to conducting transcriptome-based research in a given subject area, a valuable objective and it is a credit to all involved in the book that this goal has been largely achieved. [ A] useful reference and practical guide to conducting transcriptome research. This book is a valuable addition to the field of transcriptomics and one that the target audience will find immensely useful. --©Doodys Review Service, 2023, Mark F. Sanders, PhD (UC Davis College of Biological Sciences)
1. Transcriptomic Analysis of Gene Expression and Regulation
2. Transcriptomics and genetic engineering
3. Single cell transcriptomics
4. Time course gene expression experiments
5. Measurement and Meaning in Gene Expression Evolution
6. G-quadruplexes as key motifs in Transcriptomics
7. Spatial Transcriptomics
8. Desert plant transcriptomics and adaptation to abiotic stress
9. Transcriptomics in agricultural sciences: Capturing changes in gene regulation during abiotic or biotic stress
10. Transcriptomics in context to biotic stress
11. Functional genomics of biotic and abiotic stress responses in Capsicum
12. Transcriptomic and epigenomic insights of chicken under heat stress
13. Transcriptome Wide Identification of Immune Related Genes After Bacterial Infection in Fish
14. Human transcriptome profiling: applications in health and disease
15. Transcriptomics to devise human health and disease
16. Transcriptomics and muscle pathologies
17. Transcriptomics of Intracranial Aneurysms
18. Recent advances in transcriptomic biomarker detection for cancer
19. Future prospects of transcriptomics
Mohammad Ajmal Ali is an Associate Professor in the Department of Botany and Microbiology at King Saud University in Riyadh, Saudi Arabia, where he has taught molecular biology and bionanotechnology since 2010. He received his M.S. (1999) and Ph.D. (2006) degrees in Botany from TM Bhagalpur University in Bihar, India, and pursued postdoctoral research at Korea Research Institute of Biosciences and Biotechnology in Daejeon, South Korea. Ali's research program encompasses next-generation sequencing, computational chemistry, bioprospecting and bionanotechnology. He has authored/co-authored eight books and over 200 research articles in more than 52 journals of international repute. Joongku Lee is a Professor in the Department of Environment and Forest Resources at Chungnam National University in Daejeon, South Korea. He received Ph.D. (1998) from the Department of Biology at SungKyunKwan University, South Korea. He conducted postdoctoral work at Jepson Herbarium and Department of Integrative Biology at the University of California, Berkeley, USA. Lees present research program encompasses next-generation sequencing, bioprospecting, and plant phylogeny. He has authored/co-authored 17 books and 171 publications.