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E-book: Chemical Protein Synthesis

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  • Format: EPUB+DRM
  • Series: Methods in Molecular Biology 2530
  • Pub. Date: 27-Jun-2022
  • Publisher: Springer-Verlag New York Inc.
  • Language: eng
  • ISBN-13: 9781071624890
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  • This ebook is for personal use only. E-Books are non-refundable.
  • Format: EPUB+DRM
  • Series: Methods in Molecular Biology 2530
  • Pub. Date: 27-Jun-2022
  • Publisher: Springer-Verlag New York Inc.
  • Language: eng
  • ISBN-13: 9781071624890
Other books in subject:

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This volume provides updated protocols for chemical protein synthesis. Chapters guide readers through development methods, strategies, and applications of protein chemical synthesis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.





 





Authoritative and cutting-edge, Chemical Protein Synthesis aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge. 
Sulfated Glycoprotein Synthesis.- Total Chemical Synthesis of a
SARS-CoV-2 Miniprotein Inhibitor LCB1.- Serine/Threonine Ligation and
Cysteine/Penicillamine Ligation.- Continuous-flow synthesis of N-Methylated
Peptides via Generation of an Acyl N-Methylimidazolium Cation.- Covalent
Reactive Peptides to Block Protein Protein Interactions and Inhibit
Microbe-Host Interaction.- Ynamide-Mediated Synthetic Approach to Thioamide
Substituted Peptides.- Improved Handling of Peptide Segments Using Side
Chain-Based Helping Hand Solubilizing Tools.- Helical Stabilization of
Peptide Macrocycles by Stapled Architectures.- General solution to the
preparation of -thiolated/Selenolated Amino Acids Via Visible Light
Catalyzed Asymmetric Giese reaction.- Side-chain Anchoring Strategies for the
Synthesis of Peptide Thioesters and Selenoesters.- Preparation of
Site-Specific Succinylated Histone Mimics to Investigate ItsImpact On
Nucleosome Dynamics.- Protein Synthesis Via Activated Cysteine-Directed
Protein Ligation.- Sulfonium Tethered Peptide.- PAL-mediated Ligation for
Protein and Cell-Surface Modification.- Development of a Glycoform
Library-based Strategy to Decipher the Role of Protein Glycosylation.-
A Selenium-Based Cysteine Surrogate for Protein Chemical
Synthesis.- Removable Backbone Modification (RBM) Strategy for the Chemical
Synthesis of Hydrophobic Peptides/Proteins.