The Fifth Edition of Antimicrobial Therapy in Veterinary Medicine, the most comprehensive reference available on veterinary antimicrobial drug use, has been thoroughly revised and updated to reflect the rapid advancements in the field of antimicrobial therapy. Encompassing all aspects of antimicrobial drug use in animals, the book provides detailed coverage of virtually all types of antimicrobials relevant to animal health. Now with a new chapter on antimicrobial therapy in zoo animals, Antimicrobial Therapy in Veterinary Medicine offers a wealth of invaluable information for appropriately prescribing antimicrobial therapies and shaping public policy.
Divided into four sections covering general principles of antimicrobial therapy, classes of antimicrobial agents, special considerations, and antimicrobial drug use in multiple animal species, the text is enhanced by tables, diagrams, and photos. Antimicrobial Therapy in Veterinary Medicine is an essential resource for anyone concerned with the appropriate use of antimicrobial drugs, including veterinary practitioners, students, public health veterinarians, and industry and research scientists.
The Fifth Edition of Antimicrobial Therapy in Veterinary Medicine, the most comprehensive reference available on veterinary antimicrobial drug use, has been thoroughly revised and updated to reflect the rapid advancements in the field of antimicrobial therapy. Encompassing all aspects of antimicrobial drug use in animals, the book provides detailed coverage of virtually all types of antimicrobials relevant to animal health. Now with a new chapter on antimicrobial therapy in zoo animals, Antimicrobial Therapy in Veterinary Medicine offers a wealth of invaluable information for appropriately prescribing antimicrobial therapies and shaping public policy.
Divided into four sections covering general principles of antimicrobial therapy, classes of antimicrobial agents, special considerations, and antimicrobial drug use in multiple animal species, the text is enhanced by tables, diagrams, and photos. Antimicrobial Therapy in Veterinary Medicine is an essential resource for anyone concerned with the appropriate use of antimicrobial drugs, including veterinary practitioners, students, public health veterinarians, and industry and research scientists.
Contributors ix Preface xiii Important Notice xv Abbreviations xvii
Section I General Principles of Antimicrobial Therapy 1 1 Antimicrobial
Drug Action and Interaction: An Introduction 3 Steeve Giguere 2
Antimicrobial Susceptibility Testing Methods and Interpretation of Results 11
Joseph E. Rubin 3 Antimicrobial Resistance and its Epidemiology 21
Patrick Boerlin and David G. White 4 Principles of Antimicrobial Drug
Bioavailability and Disposition 41 J. Desmond Baggot and Steeve Giguere 5
The Pharmacodynamics of Antimicrobial Agents 79 Marilyn N. Martinez,
Pierre-Louis Toutain, and John Turnidge 6 Principles of Antimicrobial Drug
Selection and Use 105 Steeve Giguere 7 Antimicrobial Stewardship in
Animals 117 J. Scott Weese, Stephen W. Page, and John F. Prescott Section
II Classes of Antimicrobial Agents 133 8 Beta-lactam Antibiotics: Penam
Penicillins 135 John F. Prescott 9 Beta-lactam Antibiotics: Cephalosporins
153 John F. Prescott 10 Other Beta-lactam Antibiotics: Beta-lactamase
Inhibitors, Carbapenems, and Monobactams 175 John F. Prescott 11 Peptide
Antibiotics: Polymyxins, Glycopeptides, Bacitracin, and Fosfomycin 189
Patricia M. Dowling 12 Lincosamides, Pleuromutilins, and Streptogramins 199
Steeve Giguere 13 Macrolides, Azalides, and Ketolides 211 Steeve Giguere
14 Aminoglycosides and Aminocyclitols 233 Patricia M. Dowling 15
Tetracyclines 257 Jerome R.E. del Castillo 16 Chloramphenicol,
Thiamphenicol, and Florfenicol 269 Patricia M. Dowling 17 Sulfonamides,
Diaminopyrimidines, and Their Combinations 279 John F. Prescott 18
Fluoroquinolones 295 Steeve Giguere and Patricia M. Dowling 19
Miscellaneous Antimicrobials: Ionophores, Nitrofurans, Nitroimidazoles,
Rifamycins, and Others 315 Patricia M. Dowling 20 Antifungal Chemotherapy
333 Steeve Giguere Section III Special Considerations 357 21
Prophylactic Use of Antimicrobial Agents, and Antimicrobial Chemotherapy for
the Neutropenic Patient 359 Steeve Giguere, Anthony C.G. Abrams-Ogg, and
Stephen A. Kruth 22 Performance Uses of Antimicrobial Agents and
Non-antimicrobial Alternatives 379 Thomas R. Shryock and Stephen W. Page
23 Antimicrobial Therapy of Selected Organ Systems 395 Patricia M. Dowling
24 Antimicrobial Therapy of Selected Bacterial Infections 421 Steeve Giguere
25 Antimicrobial Drug Residues in Foods of Animal Origin 431 Patricia M.
Dowling 26 Regulation of Antimicrobial Use in Animals 443 Karolina Torneke
and Christopher Boland Section iv A ntimicrobial Drug Use in Selected
Animal Species 455 27 Antimicrobial Drug Use in Horses 457 Steeve Giguere
and Tiago Afonso 28 Antimicrobial Drug Use in Dogs and Cats 473 Jane E.
Sykes 29 Antimicrobial Drug Use in Cattle 495 Michael D. Apley and Johann
F. Coetzee 30 Antimicrobial Drug Use in Mastitis 519 Sarah Wagner and Ron
Erskine 31 Antimicrobial Drug Use in Sheep and Goats 529 Chris R. Clark
32 Antimicrobial Drug Use in New World Camelids 541 Christopher K. Cebra and
Margaret L. Cebra 33 Antimicrobial Drug Use in Swine 553 David G.S. Burch
34 Antimicrobial Drug Use in Poultry 569 Charles L. Hofacre, Jenny A.
Fricke, and Tom Inglis 35 Antimicrobial Drug Use in Companion Birds 589
Keven Flammer 36 Antimicrobial Drug Use in Rabbits, Rodents, and Ferrets
601 Colette L. Wheler 37 Antimicrobial Drug Use in Reptiles 623 Ramiro
Isaza and Elliott R. Jacobson 38 Antimicrobial Drug Use in Zoological
Animals 637 Ellen Wiedner and Robert P. Hunter 39 Antimicrobial Drug Use
in Aquaculture 645 Renate Reimschuessel, Ron A. Miller, and Charles M.
Gieseker Index 663
Steeve Giguere , DVM, PhD, DACVIM, is Professor of Large Animal Internal Medicine and the Marguerite Hodgson Chair in Equine Studies at the College of Veterinary Medicine, University of Georgia, in Athens, Georgia. John F. Prescott , MA, VetMB, PhD, is Professor in the Department of Pathobiology at the University of Guelph in Guelph, Ontario. Patricia M. Dowling , DVM, MS, DACVIM, DACVCP, is Professor of Veterinary Clinical Pharmacology at the University of Saskatchewan in Saskatoon, Saskatchewan.
