This volume, Antioxidant-Based Therapies for Disease Prevention and Management, presents a valuable overview of the therapeutic aspects as well as applications of antioxidants.
This informative book discusses the basic mechanisms of therapy-based oxidative damage and categorization of nutritional antioxidants. It covers the sources of antioxidants as well as their extraction and quantification. The volume considers the controversies of the usefulness or disadvantages of antioxidant supplementation in relation to adaptation and performance and also looks at the effectiveness of bioactives and antioxidant-based therapies for specific health issues, such as anemia, infectious diseases, urinary tract infections, Parkinsons diseases, and diabetes.
The book also discusses the sensing of oxidative stress and the effectiveness of antioxidant treatment, followed by an introduction to several biomarkers to estimate the bioefficacy of dietary/supplemental antioxidants in various forms. Also discussed are free radicals that can cause oxidative stress, a process that can trigger cell damage, and how antioxidant molecules have been shown to counteract oxidative stress in laboratory experiments (for example, in cells or animal studies). Several authors present studies that highlight that high-dose antioxidant supplements may be harmful in some cases. For example, the results of some studies have linked the use of high-dose beta-carotene supplements to an increased risk of lung cancer in smokers and use of high-dose vitamin E supplements to increased risks of hemorrhagic stroke (a type of stroke caused by bleeding in the brain) and prostate cancer.
With this book, sports nutrition scientists, nutritionists, food biochemists, advisors, physiologists, students, and research scholars as well as faculty will find factual information on antioxidative therapies.
Contributors |
|
ix | |
Abbreviations |
|
xi | |
Foreword |
|
xiii | |
Preface |
|
xv | |
Introduction |
|
xvii | |
Acknowledgment |
|
xix | |
|
1 Nano-Antioxidants, A Next-Generation Therapeutic Strategy |
|
|
1 | (20) |
|
|
|
|
2 Role of Phytomedicine in the Challenges to Combat Anemia |
|
|
21 | (32) |
|
|
3 Role of Free Radicals during Infection and the Advancement of Antioxidants to Improve the Treatment of Infectious Diseases |
|
|
53 | (24) |
|
|
|
|
4 Role of Antioxidants in Diabetes |
|
|
77 | (20) |
|
|
|
|
|
5 Extraction and Quantification of Antioxidants |
|
|
97 | (30) |
|
|
|
6 Comparative Estimation of Antioxidant and Antimicrobial Activity of Bioactive Components with Special Reference to Urinary Tract Infection |
|
|
127 | (18) |
|
|
|
|
7 Citrus Fruits and Their By-Products, Power House of Remedial Antioxidants |
|
|
145 | (38) |
|
|
|
|
8 Antioxidative Defense System in Plants |
|
|
183 | (20) |
|
|
|
|
|
9 Bryophytes, An Extensive Source of Antioxidants |
|
|
203 | (18) |
|
|
10 Natural Antioxidants in the Management of Alzheimer's Disease |
|
|
221 | (18) |
|
|
11 Oxidative Stress and Parkinson's Diseases, A Role of Current Therapies |
|
|
239 | (14) |
|
|
|
|
12 Solatium lycopersicum, a Reservoir of Antioxidants |
|
|
253 | (16) |
|
|
|
Index |
|
269 | |
Pallavi Singh Chauhan, PhD, is Assistant Professor at the Amity Institute of Biotechnology, Amity University Madhya Pradesh, Gwalior, India, as well as a researcher. Her research focuses on the synthesis, characterization, and multiple biomedical application of nanoparticles. The major fields of science that are relevant to Dr. Chauhans work include nanotechnology, nanobioscience, biomedical application of nanotechnology, nanotoxicity, magnetic nanostructures, nanocatalysts, and nanoparticle systems of metals and metal oxides.
Sonia Johri, PhD, is Dean of Academics and Associate Professor in the Department of Life Sciences at ITM University, Gwalior, Madhya Pradesh, India. She has over 40 papers to her credit in journals of national and international repute. She is an external member of the Board of Studies in Biochemistry at Jiwaji University and a member of the Institutional Animal Ethical Committee at ITM University, Gwalior. She has authored a book entitled Practical Biochemistry, and she is a reviewer for various national and international journals. Dr. Johri has 23 years of research experience and has worked extensively in the diversified fields of metal toxicity, anemia, hepatoprotection, oxidative stress, and biofuels.