Most people who develop dementia will never be diagnosed, and therefore lack access to treatment and care from specialists in the field. This new edition provides updated guidance on how behavioral symptom reflect the changes occurring in the brain, and how these can help generalist clinicians to accurately diagnose neurodegenerative diseases. This practical book is aimed at healthcare professionals working in neurology, psychiatry and neuropsychology wanting to enhance the skills and knowledge needed to successfully manage these diseases. Simple approaches to bedside mental status testing, differential diagnosis and treatment, and interpreting neuropsychological testing and neuroimaging findings are covered. Introductory chapters outline dementia epidemiology and dementia neuropathology whilst chapters new to this edition describe the improvements in diagnostic capabilities in recent years, including blood based and cerebrospinal biomarkers and emerging biologically based therapies. Chapters on sleep disorders, and chronic traumatic encephalopathy and traumatic brain injury have also been expanded.
Daugiau informacijos
Describes the latest research into the behavioral symptoms of dementia helping to accurately diagnose and manage neurodegenerative diseases.
Part I. Introductory
Chapters on Dementia:
1. Dementia at the bedside
Bradley F. Boeve and Bruce L. Miller;
2. Brief cognitive assessment Elena
Tsoy, Katherine Possin;
3. Neuropsychiatric symptoms of dementia Yavuz Ayhan,
Bruce L Miller;
4. Neuropathology of dementia Eun-Joo Kim, Sarat Vatsavayai
and William W. Seeley;
5. Neurotransmitters and neuromodulators in dementia
Neus Falgąs Martķnez, Caroline Lew, Alejandra Sįnchez López, Cathrine
Petersen and Lea T. Grinberg;
6. Cerebrospinal fluid, molecular neuroimaging,
and blood biomarkers of neurodegenerative disease: past, present, and future
David N. Soleimani-Meigoon and Gil D. Rabinovici;
7. Magnetic resonance
imaging in dementia Chloe Anastassiadis, Howard Rosen and Maria Carmela
Tartaglia;
8. Epidemiology and risk-factors for dementia Christina S.
Dintinca and Kristine Yaffe;
9. Genetic approaches to neurodegenerative
disease Leonel T. Takada and Jennifer Yokoyama; Part II. The Dementias:
10.
Alzheimer's disease: preclinical to advanced dementia Neus Falgas Martinez
and Raquel Sįnchez del Valle Dķaz;
11. The behavioral variant of
frontotemporal dementia: preclinical to advanced dementia Ignacio Illan-Gala
and Bruce L. Miller;
12. Early features of primary progressive aphasia
Zachary A. Miller, Gaia C. Santi and Maria Luisa Gorno Tempini;
13. The
Cognitive neurology of corticobasal degeneration and progressive supranuclear
palsy Suzee E. Lee and Carolyn Fredericks;
14. Mild cognitive impairment
across the dementias Ronald C. Peterson;
15. Cognitive disorders of the very
old: from clinic to pathology Victor Valcour and Lea T. Grinberg;
16.
Posterior cortical atrophy Zeinab Abdi, Emma Harding, Victoria Pelak, Keir X.
X. Yong and Sebastian J Crutch;
17. Cognitive and behavioral abnormalities of
vascular cognitive impairment Hyemin Jang, Jee Hyang Jeong, Eun-Joo Kim, Duk
L. Na and Sang Won Seo;
18. Creutzfeldt-Jakob disease and other prion
diseases Igor Prufer Araujo and Michael D. Geschwind;
19. Chronic traumatic
encephalopathy Breton M. Asken, David C. Perry and Raquel C. Gardner;
20.
Normal pressure hydrocephalus Neill R. Graff-Radford and Benjamin D. Elder;
Part iii. Treatment of the Dementias:
21. Treatment of alzheimer's disease
Jeffrey L. Cummings;
22. Treatment of frontotemporal dementia Doris Chen,
Lawren VandeVrede and Adam L. Boxer;
23. Treatment of dementia with lewy body
Bradley F. Boeve;
24. Delirium masquerading as dementia Sara C. LaHue and S.
Andrew Josephson;
25. Sleep issues in dementia Sandra Giménez and Bradley F.
Boeve;
26. Caregiving in dementia Jennifer Merrilees, Sarah Dulaney and
Robert W. Levenson;
27. Legal Issues in dementia Jalayne Arias, Megan Wright
and Ana Tylor.
Bruce L. Miller is the Clausen Distinguished Professor in Neurology at University of California, San Francisco, Director of the Memory and Aging Center, and Founding Director of the Global Brain Health Institute. He received the Potamkin Award and Lifetime Achievement Award in Alzheimer's Disease and was elected to the National Academy of Medicine. Bradley F. Boeve is fellowship-trained in behavioral neurology and sleep medicine. He holds the academic rank of Professor of Neurology, Mayo Clinic, and is recognized with the distinction of the Little Family Foundation Professorship in Lewy Body Dementia. His clinical and research interests include Alzheimer's disease, Parkinson's disease, and particularly the non-Alzheimer's degenerative dementias and the neurologically-based sleep disorders.
