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Biocomputing 2013 - Proceedings Of The Pacific Symposium [Kietas viršelis]

Edited by (Stanford Univ, Usa), Edited by (Indiana Univ, Usa), Edited by (Univ Of Colorado Health Sciences Center, Usa), Edited by (Stanford Univ, Usa), Edited by (Stanford Univ, Usa)
  • Formatas: Hardback, 472 pages
  • Išleidimo metai: 16-Nov-2012
  • Leidėjas: World Scientific Publishing Co Pte Ltd
  • ISBN-10: 9814596361
  • ISBN-13: 9789814596367
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 472 pages
  • Išleidimo metai: 16-Nov-2012
  • Leidėjas: World Scientific Publishing Co Pte Ltd
  • ISBN-10: 9814596361
  • ISBN-13: 9789814596367
Kitos knygos pagal šią temą:
The Pacific Symposium on Biocomputing (PSB) 2013 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2013 will be held on January 3 – 7, 2013 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2013 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.
Preface v
COMPUTATIONAL DRUG REPOSITIONING
Session Introduction
1(4)
Zhiyong Lu
Pankaj Agarwal
Atul Butte
Evaluation of Analytical Methods for Connectivity Map Data
5(12)
Jie Cheng
Qing Xie
Vinod Kumar
Mark Hurle
Johannes M. Freudenberg
Lun Yang
Pankaj Agarwal
Predictive Systems Biology Approach to Broad-Spectrum, Host-Directed Drug Target Discovery in Infectious Diseases
17(12)
Ramon M. Felciano
Sina Bavari
Daniel R. Richards
Jean-Noel Billaud
Travis Warren
Rekha Panchal
Andreas Kramer
A Novel Multi-Modal Drug Repurposing Approach for Identification of Potent ACK1 Inhibitors
29(12)
Sharangdhar S. Phatak
Shuxing Zhang
Protein-chemical Interaction Prediction via Kernelized Sparse Learning SVM
41(12)
Yi Shi
Xinhua Zhang
Xiaoping Liao
Guohui Lin
Dale Schuurmans
Drug Target Predictions Based on Heterogeneous Graph Inference
53(12)
Wenhui Wang
Sen Yang
Jing Li
EPIGENOMICS
Session Introduction
65(4)
Alexander J. Hartemink
Manolis Kellis
William Stafford Noble
Zhiping Weng
A Powerful Statistical Method for Identifying Differentially Methylated Markers in Complex Diseases
69(11)
Surin Ahn
Tao Wang
Using DNase Digestion Data to Accurately Identify Transcription Factor Binding Sites
80(12)
Kaixuan Luo
Alexander J. Hartemink
Epigenomic Model of Cardiac Enhancers with Application to Genome Wide Association Studies
92(11)
Avinash Das Sahu
Radhouane Aniba
Yen-Pei Christy Chang
Sridhar Hannenhalli
IDENTIFICATION OF ABERRANT PATHWAY AND NETWORK ACTIVITY FROM HIGH-THROUGHPUT DATA
Session Introduction
103(8)
Rachel Karchin
Michael F. Ochs
Joshua M. Stuart
Trey Ideker
Joel S. Bader
From Uncertain Protein Interaction Networks to Signaling Pathways Through Intensive Color Coding
111(12)
Haitham Gabr
Alin Dobra
Tamer Kahveci
Identifying Master Regulators of Cancer and Their Downstream Targets by Integrating Genomic and Epigenomic Features
123(12)
Olivier Gevaert
Sylvia Plevritis
Module Cover -- A New Approach to Genotype-Phenotype Studies
135(12)
Yoo-Ah Kim
Raheleh Salari
Stefan Wuchty
Teresa M. Przytycka
Next-Generation Analysis of Cataracts: Determining Knowledge Driven Gene-Gene Interactions Using Biofilter, and Gene-Environment Interactions Using the PhenX Toolkit
147(12)
Sarah A. Pendergrass
Shefali S. Verma
Emily R. Holzinger
Carrie B. Moore
John Wallace
Scott M. Dudek
Wayne Huggins
Terrie Kitchner
Carol Waudby
Richard Berg
Catherine A. McCarty
Marylyn D. Ritchie
Interpreting Personal Transcriptomes: Personalized Mechanism-Scale Profiling of RNA-seq Data
159(12)
Alan Perez-Rathke
Haiquan Li
Yves A. Lussier
PERSONALIZED MEDICINE: FROM GENOTYPES AND MOLECULAR PHENOTYPES TOWARDS THERAPY
Session Introduction
171(4)
Oliver Stegle
Steven E. Brenner
Quaid Morris
Jennifer Listgarten
AMP: Assembly Matching Pursuit
175(13)
Surojit Biswas
Vladimir Jojic
Characterization of the Metabochip in Diverse Populations from the International HapMap Project in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) Project
188(12)
Dana C. Crawford
Robert Goodloe
Kristin Brown-Gentry
Sarah Wilson
Jamie Roberson
Niloufar B. Gillani
Marylyn D. Ritchie
Holli H. Dilks
William S. Bush
Insights into Diseases of Human Telomerase from Dynamical Modeling
200(12)
Samuel Coulbourn Flores
Christina Waldsich
Spectral Clustering Strategies for Heterogeneous Disease Data
212(12)
Grace T. Huang
Kathryn I. Cunningham
Panayiotis V. Benos
Chakra S. Chennubhotla
Systematic Identification of Risk Factors for Alzheimer's Disease Through Shared Genetic Architecture and Electronic Medical Records
224(12)
Li Li
David Ruau
Rong Chen
Susan Weber
Atul J. Butte
A Correlated Meta-Analysis Strategy for Data Mining "Omic" Scans
236(11)
Michael A. Province
Ingrid B. Borecki
PHYLOGENOMICS AND POPULATION GENOMICS: MODELS, ALGORITHMS, AND ANALYTICAL TOOLS
Session Introduction
247(3)
Luay Nakhleh
Noah Rosenberg
Tandy Warnow
Inferring Optimal Species Trees Under Gene Duplication and Loss
250(12)
M. S. Bayzid
Siavash Mirarab
Tandy Warnow
Evaluating Variations on the STAR Algorithm for Relative Efficiency and Sample Sizes Needed to Reconstruct Species Trees
262(11)
James H. Degnan
The Behavior of Admixed Populations in Neighbor-Joining Inference of Population Trees
273(12)
Naama M. Kopelman
Lewi Stone
Olivier Gascuel
Noah A. Rosenberg
Maximum Likelihood Phylogenetic Reconstruction from High-Resolution Whole-Genome Data and a Tree of 68 Eukaryotes
285(12)
Yu Lin
Fei Hu
Jijun Tang
Bernard M.E. Moret
An Analytical Comparison of Multilocus Methods Under the Multispecies Coalescent: The Three-Taxon Case
297(10)
Sebastien Roch
POST-NGS: INTERPRETATION AND ANALYSIS OF NEXT GENERATION SEQUENCING DATA FOR BASIC AND TRANSLATIONAL SCIENCE
Session Introduction
307(3)
Gurkan Bebek
Mehmet Koyuturk
Thomas LaFramboise
Benjamin J. Raphael
Mark R. Chance
LSHPlace: Fast Phylogenetic Placement Using Locality-Sensitive Hashing
310(10)
Daniel G. Brown
Jakub Truszkowski
ChIPModule: Systematic Discovery of Transcription Factors and Their Cofactors from ChIP-seq Data
320(12)
Jun Ding
Xiaohui Cai
Ying Wang
Haiyan Hu
Xiaoman Li
Using BioBin to Explore Rare Variant Population Stratification 332