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Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation 3rd edition [Minkštas viršelis]

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, (Associate Professor and Undergraduate Program Director, Department of Biomedical Engineering, Stony Br), (Associate Professor and Graduate Program Director, Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY.)
  • Formatas: Paperback / softback, 632 pages, aukštis x plotis: 235x191 mm, weight: 930 g
  • Serija: Biomedical Engineering
  • Išleidimo metai: 05-Jul-2021
  • Leidėjas: Academic Press Inc
  • ISBN-10: 012818034X
  • ISBN-13: 9780128180341
Kitos knygos pagal šią temą:
Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation 3rd editionDidesnis paveikslėlis
  • Formatas: Paperback / softback, 632 pages, aukštis x plotis: 235x191 mm, weight: 930 g
  • Serija: Biomedical Engineering
  • Išleidimo metai: 05-Jul-2021
  • Leidėjas: Academic Press Inc
  • ISBN-10: 012818034X
  • ISBN-13: 9780128180341
Kitos knygos pagal šią temą:
Pastovi nuoroda: https://www.kriso.lt/db/9780128180341.html
Raktažodžiai:

Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation, Third Edition shows how fluid mechanics principles can be applied not only to blood circulation, but also to air flow through the lungs, joint lubrication, intraocular fluid movement, renal transport, and other specialty circulations. This new edition contains new homework problems and worked examples, including MATLAB-based examples. In addition, new content has been added on such relevant topics as Womersley and Oscillatory Flows. With advanced topics in the text now denoted for instructor convenience, this book is particularly suitable for both senior and graduate-level courses in biofluids.

  • Uses language and math that is appropriate and conducive for undergraduate and first-year graduate learning
  • Contains new worked examples and end-of-chapter problems
  • Covers topics in the traditional biofluids curriculum, also addressing other systems in the body
  • Discusses clinical applications throughout the book, providing practical applications for the concepts discussed
  • Includes more advanced topics to help instructors teach an undergraduate course without a loss of continuity in the class
Preface xi
I Fluid mechanics basics
1 Introduction
1.1 Note to students about this textbook
3(2)
1.2 Biomedical engineering
5(1)
1.3 Scope of fluid mechanics
6(1)
1.4 Scope of biofluid mechanics
7(2)
1.5 Dimensions and units
9(3)
1.6 Salient biofluid mechanics dimensionless numbers
12(3)
Summary
15(1)
Reference
16(1)
2 Fundamentals of fluid mechanics
2.1 Fluid mechanics introduction
17(4)
2.2 Fundamental fluid mechanics equations
21(5)
2.3 Analysis methods
26(4)
2.4 Fluid as a continuum
30(3)
4.2.5 Elemental stress and pressure
33(5)
2.6 Kinematics: Velocity, acceleration, rotation, and deformation
38(10)
2.7 Viscosity
48(2)
2.8 Fluid motions
50(3)
2.9 Two-phase flows
53(3)
2.10 Changes in the fundamental relationships on the microscale
56(1)
2.11 Fluid structure interaction
57(2)
2.12 Introduction to turbulent flows and the relationship of turbulence to biological systems
59(3)
Summary
62(3)
Home work problems
65(4)
References
69(2)
3 Conservation laws
3.1 Fluid statics equations
71(10)
3.2 Buoyancy
81(2)
3.3 Conservation of mass
83(10)
3.4 Conservation of momentum
93(5)
3.5 Momentum equation with acceleration
98(6)
3.6 The first and second laws of thermodynamics
104(6)
3.7 The Navier-Stokes equations
110(8)
3.8 Bernoulli equation
118(5)
Summary
123(2)
Home work problems
125(6)
Reference
131(4)
II Macrocirculation
4 Introduction to heat transfer
4.1 Thermodynamics and engineering heat transfer
135(3)
4.2 Heat and energy considerations
138(3)
4.3 Energy transfer and balances
141(3)
4.4 Mechanisms of heat transfer
144(7)
4.5 General heat transfer equations
151(2)
Summary
153(1)
Homework problems
154(2)
References
156(1)
5 The heart
5.1 Cardiac physiology
157(10)
5.2 Cardiac conduction system and electrocardiogram
167(4)
5.3 The cardiac cycle
171(4)
5.4 Heart motion
175(5)
5.5 Heart valve function
180(6)
5.6 Heart valve dynamics
186(3)
5.7 Disease conditions
189(10)
5.7.1 Coronary artery disease
190(3)
5.7.2 Myocardial infarction
193(1)
5.7.3 Heart valve diseases
194(3)
5.7.4 Congenital heart diseases
197(2)
Summary
199(3)
Homework problems
202(2)
References
204(4)
6 Blood flow in arteries and veins
6.1 Arterial system physiology
208(3)
6.2 Venous system physiology
211(3)
6.3 Blood cells and plasma
214(6)
6.4 Blood rheology
220(6)
6.5 Pressure, flow, and resistance: arterial system
226(4)
6.6 Pressure, flow, and resistance: venous system
230(4)
6.7 Windkessel model for blood flow
234(5)
6.8 Wave propagation in arterial circulation
239(6)
6.9 Flow separation at bifurcations and at walls
245(5)
6.10 Flow through tapering and curved channels
250(7)
6.11 Pulsatile flow and turbulence
257(6)
6.12 Womersley flow and solution
263(5)
6.13 Oscillatory blood flow and oscillatory shear index
268(1)
6.14 Disease conditions
269(6)
6.14.1 Arteriosclerosis, stroke, and high blood pressure
269(3)
6.14.2 Platelet activation and thromboembolism
272(1)
6.14.3 Aneurysm
273(2)
Summary
275(5)
Homework problems
280(2)
References
282(6)
III Microcirculation
7 Microvascular beds
7.1 Microcirculation physiology
288(4)
7.2 Endothelial cell and smooth muscle cell physiology
292(3)
7.3 Local control of blood flow
295(3)
7.4 Pressure distribution throughout the microvascular beds
298(2)
7.5 Velocity distribution throughout the microvascular beds
300(6)
7.6 Interstitial space pressure and velocity
306(3)
7.7 Hematocrit/Fahraeus-Lindquist effect/Fahraeus effect
309(3)
7.8 Plug flow in capillaries
312(4)
7.9 Characteristics of two-phase flow
316(2)
7.10 Interactions between cells and the vessel wall
318(3)
7.11 Disease conditions
321(2)
7.11.1 Shock and tissue necrosis
321(1)
7.11.2 Edema
322(1)
Summary
323(4)
Homework problems
327(2)
References
329(3)
8 Mass transport and heat transfer in the microcirculation
8.1 Gas diffusion
332(10)
8.2 Glucose transport
342(1)
8.3 Vascular permeability
343(4)
8.4 Energy considerations
347(5)
8.5 Transport through porous media
352(3)
8.6 Microcirculatory heat transfer
355(10)
8.7 Cell transfer during inflammation and white blood cell rolling and sticking
365(2)
Summary
367(5)
Homework problems
372(1)
References
373(2)
9 The lymphatic system
9.1 Lymphatic physiology
375(4)
9.2 Lymph formation
379(1)
9.3 Flow through the lymphatic system
380(4)
9.4 Disease conditions
384(3)
9.4.1 Cancer metastasis by the lymphatic system
384(2)
9.4.2 Lymphedema
386(1)
Summary
387(1)
Homework problems
388(1)
References
389(4)
IV Specialty circulations
10 Flow in the lungs
10.1 Lung physiology
393(6)
10.2 Elasticity of the lung blood vessels and alveoli
399(2)
10.3 Pressure-volume relationship for airflow in the lungs
401(2)
10.4 Cardiopulmonary flows: ventilation perfusion matching
403(1)
10.5 Oxygen and carbon dioxide diffusion
404(5)
10.6 Oxygen and carbon dioxide transport in the blood
409(2)
10.7 Compressible fluid flow
411(2)
10.8 Disease conditions
413(2)
10.8.1 Emphysema
413(1)
10.8.2 Asthma
414(1)
10.8.3 Tuberculosis
415(1)
Summary
415(3)
Homework problems
418(2)
References
420(3)
11 Intraocular fluid flow
11.1 Eye physiology
423(3)
11.2 Eye blood supply, circulation, and drainage
426(3)
11.3 Aqueous humor formation
429(1)
11.4 Aquaporins
430(2)
11.5 Flow of aqueous humor
432(2)
11.6 Intraocular pressure
434(2)
11.7 Disease conditions
436(1)
11.7.1 Glaucoma
436(1)
11.7.2 Cataracts
437(1)
Summary
438(2)
Homework problems
440(1)
References
441(2)
12 Lubrication of joints and transport in bone
12.1 Skeletal physiology
443(7)
12.2 Bone vascular anatomy and fluid phases
450(1)
12.3 Formation of synovial fluid
451(2)
12.4 Synovial fluid flow
453(3)
12.5 Mechanical forces within joints
456(6)
12.6 Transport of molecules in bone
462(2)
12.7 Disease conditions
464(1)
12.7.1 Synovitis
464(1)
12.7.2 Bursitis and tenosynovitis
465(1)
Summary
465(3)
Homework problems
468(2)
References
470(3)
13 Flow through the kidney
13.1 Kidney physiology
473(5)
13.2 Distribution of blood in the kidney
478(3)
13.3 Glomerular filtration and dynamics
481(5)
13.4 Tubule reabsorption and secretion
486(4)
13.5 Single nephron filtration rate
490(2)
13.6 Peritubular capillary flow
492(1)
13.7 Sodium balance and transport of important molecules
493(3)
13.8 Autoregulation of kidney blood flow
496(2)
13.9 Compartmental analysis for urine formation
498(3)
13.10 Extracorporeal flows: dialysis
501(4)
13.11 Disease conditions
505(2)
13.11.1 Renal calculi
505(1)
13.11.2 Kidney disease
506(1)
Summary
507(2)
Homework problems
509(3)
References
512(3)
14 Splanchnic circulation: liver and spleen
14.1 Liver and spleen physiology
515(6)
14.2 Hepatic and splenic blood flow
521(1)
14.3 Hepatic and splenic microcirculation
522(1)
14.4 Storage and release of blood in the liver
523(2)
14.5 Active and passive components of the splanchnic circulation
525(1)
14.6 Innervation of the spleen
526(1)
14.7 Disease conditions
527(1)
14.7.1 Hepatitis
527(1)
14.7.2 Alcoholic and fatty liver disease
527(1)
14.7.3 Splenomegaly
528(1)
Summary
528(2)
Homework problems
530(1)
References
531(4)
V Modeling and experimental techniques
15 In silico biofluid mechanics
15.1 Computational fluid dynamics
535(13)
15.2 Fluid structure interaction modeling
548(5)
15.3 Buckingham Pi Theorem and dynamic similarity
553(8)
15.4 Current state of the art for biofluid mechanics in silico research
561(2)
15.5 Future directions of biofluid mechanics in silico research
563(1)
Summary
564(3)
Homework problems
567(1)
References
568(5)
16 In vitro biofluid mechanics
16.1 Particle imaging velocimetry
573(3)
16.2 Laser Doppler velocimetry
576(2)
16.3 Flow chambers: parallel plate and cone-and-plate viscometry
578(2)
16.4 Lab-on-a-chip and lithography
580(3)
16.5 Current state of the art for biofluid mechanics in vitro research
583(2)
16.6 Future directions of biofluid mechanics in vitro research
585(1)
Summary
586(1)
Homework problems
587(1)
References
587(4)
17 In vivo biofluid mechanics
17.1 Live animal preparations
591(3)
17.2 Doppler ultrasound
594(3)
17.3 Phase contrast magnetic resonance imaging
597(1)
17.4 Review of other techniques
598(1)
17.5 Current state of the art for biofluid mechanics in vivo research
599(1)
17.6 Future directions of biofluid mechanics in vivo research
600(2)
Summary
602(1)
Homework problems
603(1)
References
603(2)
Further readings 605(2)
Index 607
Dr. Rubenstein focuses on two major research areas: vascular tissue engineering and the initiation/progression of cardiovascular diseases mediated through platelet and endothelial cell interactions. Dr. Yin conducts research into coronary artery disease, specifically how altered blood flow and stress distribution affect platelet and endothelial cell behavior and lead to cardiovascular disease initiation. The focus of Dr. Frames research is in integrating signal transduction events with physical properties of blood flow at the microvascular level, with the long term research goal of understanding the two phase question of how solute distribution and transport are coupled in the microcirculation.