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Protein Adsorption to Biomatrials |
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2 | (1) |
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Fundamentals of Protein Adsorption |
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2 | (9) |
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2 | (1) |
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3 | (4) |
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7 | (3) |
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10 | (1) |
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Adsorption of Serum Proteins |
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10 | (1) |
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Techniques for the Study of Protein Adsorption |
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11 | (4) |
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Established Techniques for the Study of Protein Adsorption |
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11 | (2) |
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Emerging Techniques for the Study of Protein Adsorption |
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13 | (2) |
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Recent Advances in Protein Adsorption |
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15 | (2) |
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Protein Adsorption to Nanomaterials |
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15 | (1) |
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Manipulating Protein Adsorption |
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16 | (1) |
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Current Limitations and Potential Future Opportunities |
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17 | (3) |
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17 | (3) |
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Investigating Protein Adsorption via Spectroscopic Ellipsometry |
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20 | (1) |
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21 | (1) |
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Optical Models Used to Interpret Ellipsometric Results |
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22 | (2) |
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Instrument Considerations |
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24 | (2) |
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Material Surface Preparation |
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26 | (1) |
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Typical Protein Adsorption Experiment Followed by Ellipsometry |
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26 | (2) |
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Ellipsometric Determination of the Adsorption of Proteins to Nanomaterials |
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28 | (5) |
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Adsorption of BSA to Nanostructured TiO2 |
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28 | (3) |
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Adsorption of Proteins to Carbon Nanotubes: Biosensing Applications |
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31 | (2) |
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33 | (1) |
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34 | (10) |
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35 | (9) |
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Atomic Force Microscopy Methods for Characterizing Protein Interactions with Microphase-Separated Polyurethane Biomaterials |
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44 | (3) |
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Surface Microphase Separation Structures of PU Materials |
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47 | (3) |
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Microphase Structure of PU Under Ambient Environments |
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47 | (1) |
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Microphase Structure of PU Under Aqueous Buffer Conditions |
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48 | (1) |
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Micromechanical Analysis of PU Materials by AFM Indentation |
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49 | (1) |
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Protein Interactions with Hydrophobic and Hydrophilic Surfaces |
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50 | (6) |
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Time-Dependent Conformational Changes in Fibrinogen Measured by AFM |
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51 | (1) |
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Effects of Surface Wettability and Contact Time on Protein Adhesion to Materials |
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52 | (2) |
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Dynamic Force Microscopy Studies of Fibrinogen-Material Surface Interactions |
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54 | (2) |
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Recognition of Proteins on Material Surfaces by AFM |
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56 | (2) |
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Immunological Recognition of Protein with Polyclonal Antibodies by AFM Force Mode |
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56 | (1) |
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Immunological Nanogold Labeling Technique |
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57 | (1) |
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Measuring the Functional Activity of Adsorbed Fibrinogen |
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58 | (1) |
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Measuring Protein Adsorption on PU Surfaces at the Molecular Scale |
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59 | (2) |
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Microphase Separation Structure Affects Protein Adsorption |
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59 | (1) |
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Soft Segment Chemistry and Hard Segment Content of PUs Affect Fibriongen Adsorption/Bioactivity and Platelet Adhesion |
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60 | (1) |
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61 | (9) |
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63 | (7) |
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Molecular Simulation of Protein-Surface Interactions |
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70 | (1) |
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Fundamentals of Protein Structure and Protein-Surface Interactions |
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71 | (3) |
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Molecular Simulation Methods |
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74 | (17) |
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74 | (1) |
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Molecular Simulation of Protein-Surface Interactions |
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75 | (7) |
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Representation of Solvation Effects for Protein-Surface Interactions |
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82 | (4) |
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Statistical Sampling Considerations for Protein-Surface Interactions |
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86 | (5) |
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91 | (1) |
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91 | (7) |
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92 | (6) |
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Biomolecule-Nanomaterial Interactions: Effect on Biomolecule Structure, Function, and Stability |
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98 | (1) |
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Structure and Function of Proteins on Carbon Nanotubes |
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99 | (3) |
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Enhanced Protein Stability on Nanomaterials |
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102 | (3) |
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105 | (7) |
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Polymer---Nanotube---Enzyme Composites for Antifouling Applications |
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105 | (1) |
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Nanotube-Assisted Protein Deactivation |
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106 | (2) |
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Protein-Mediated Formation of Nanotube---Nanoparticle Hybrid Materials |
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108 | (1) |
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Nanotube-Directed Interfacial Biocatalysis |
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108 | (2) |
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Solubilization of SWNTs Using Proteins |
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110 | (1) |
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DNA Degradation by MWNT-DNAzyme Hybrids |
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110 | (2) |
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Conclusion and Future Directions |
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112 | (4) |
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113 | (3) |
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Phage Display as a Strategy for Designing Organic/Inorganic Biomaterials |
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Introduction: Biomaterials Development and the Need for More Robust Approaches to Control Protein, Cell, and Tissue Responses |
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116 | (2) |
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Peptide---Biomaterial Interaction |
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118 | (1) |
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Phage Display as a Selection Technique |
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119 | (4) |
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Computational Analysis Tools |
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122 | (1) |
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Characterization Techniques |
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123 | (1) |
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Phage Display on Apatite-Based Mineral |
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123 | (2) |
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Phage Display on Cells and the Role of Dual-Functioning Peptides |
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125 | (2) |
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Advancing Phage Display in Biomaterials Research - Summary |
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127 | (7) |
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127 | (7) |
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Extracellular Matrix-Derived Lignds for Selective Integrin Binding to Control Cell Function |
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Extracellular Matrix: Composition and Role |
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134 | (1) |
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Cell-ECM Adhesive Interactions: Integrins as Pivotal Linkers |
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135 | (3) |
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Engineering Biomaterial Surface Properties for Integrin Binding |
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138 | (2) |
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Modulating Cellular Response to Biomaterial Surfaces Through ECM-Mimetic Surface Modification Strategies |
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140 | (9) |
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General ECM Surface Modifications to Regulate Integrin-Mediated Cell Function |
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140 | (2) |
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Small Biomimetic Peptide Surface Strategies |
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142 | (2) |
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Multiple-Motif Integrin-Specific Ligands |
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144 | (1) |
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FN-Derived Highly Selective Integrin Ligands |
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145 | (2) |
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Collagen-Mimetic Integrin-Specific Ligands |
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147 | (1) |
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FN-Derived Integrin Ligands to Direct Matrix Assembly |
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148 | (1) |
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Advanced ECM-Mimetic Surface Strategies: Multivalent, Clustered Integrin Ligands |
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149 | (2) |
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151 | (7) |
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151 | (7) |
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Ligand-Functionalized Biomaterial Surfaces: Controlled Regulation of Signaling Pathways to Direct Stem Cell Differentiation |
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158 | (1) |
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158 | (9) |
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Biological Strategy for Inducing Notch Signaling In Vitro: Notch Ligand-Transfected Stromal Cells for T-Cell Differentiation |
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159 | (3) |
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Ligand Presentation Through the Cell Surface Is Not Necessary for Notch Signaling: Immobilization of Notch Ligand on Synthetic Surfaces for Notch Signal Activation |
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162 | (2) |
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Method to Scale-Up Notch Signaling and Mimic Cell-Cell Interactions: Microbead-Based Notch Signaling for T-Cell Differentiation |
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164 | (3) |
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Other Signal Transduction Pathways |
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167 | (2) |
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167 | (1) |
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Fibronectin-Immobilized Biomaterial Surface to Induce Mesenchymal Stem Cell Differentiation and HSC Expansion |
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168 | (1) |
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169 | (5) |
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170 | (4) |
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Growth Factors on Biomaterial Scaffolds |
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174 | (1) |
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Mechanisms of Action of Growth Factors on Cells |
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174 | (2) |
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Immobilized Growth Factors |
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176 | (5) |
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Effects of Immobilized Growth Factors on Cell Function |
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181 | (6) |
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High Local Concentration of Growth Factors and Multivalency |
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182 | (2) |
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Inhibition of Growth Factor Downregulation |
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184 | (1) |
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Other Pertinent Mechanisms |
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185 | (2) |
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Biomaterial Design Using Immobilized Growth Factors |
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187 | (5) |
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Methods for Growth Factor Immobilization |
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187 | (1) |
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Spacer Insertion and Surface Stiffness |
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188 | (1) |
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188 | (1) |
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189 | (1) |
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Engineering of Proteins for Immobilization |
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190 | (2) |
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192 | (8) |
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192 | (8) |
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Cell and Tissue Interactions with Materials: The Role of Growth Factors |
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200 | (1) |
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Growth Factors in Vascular Network Formation and Repair |
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201 | (5) |
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Vascular Endothelial Growth Factor (VEGF) |
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202 | (1) |
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Fibroblast Growth Factor (FGF) |
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203 | (1) |
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Platelet-Derived Growth Factor (PDGF) |
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204 | (1) |
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Transforming Growth Factor-β (TGF-β) |
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204 | (1) |
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Growth Factors in the Wound-Healing Process of Vascular Tissue |
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205 | (1) |
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Growth Factors in Select Pathological Conditions Pertinent to Vascularization |
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206 | (1) |
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Growth Factors in Bone Development and Repair |
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206 | (4) |
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206 | (1) |
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Bone Morphogenetic Protein |
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207 | (1) |
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Fibroblast Growth Factor (FGF) |
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208 | (1) |
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Insulin-Like Growth Facctor (IGF) |
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208 | (1) |
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Platelet-Derived Growth Factor (PDGF) |
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208 | (1) |
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Transforming Growth Factor-β (TGF-β) |
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208 | (1) |
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Growth Factors in the Wound-Healing Process of Bone |
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209 | (1) |
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Future Directions in Growth Factor Research |
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210 | (1) |
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Applications of Growth Factors to Biomaterials |
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210 | (7) |
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Modes of Growth Factor Delivery from Biomaterials |
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211 | (2) |
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Combined Delivery of Growth Factors |
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213 | (2) |
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Combined Angiogenic/Osteogenic Growth Factor Delivery |
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215 | (1) |
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Sequential Delivery of Growth Factors |
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216 | (1) |
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State of the Art Summary and Future Dirctions |
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217 | (9) |
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218 | (8) |
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In Vitro and In Vivo Monocyte, Macrophage, Foreign Body Giant Cell, and Lymphocyte Interactions with Biomaterials |
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226 | (2) |
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Monocytes, Macrophages, and FBGCs |
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228 | (6) |
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Protein Adsorption on Biomaterial Surfaces |
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228 | (1) |
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Monocyte/Macrophage Migration and Adhesion |
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228 | (3) |
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Macrophage Fusion/FBGC Formation |
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231 | (1) |
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231 | (1) |
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Consequences of FBGC Formation on Biomaterial Surfaces |
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232 | (2) |
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Paracrine Interactions Between Macrophages/FBGCs and Inflammatory/Wound-Healing Cells |
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234 | (4) |
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Macrophage/FBGC and Cytokines |
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234 | (3) |
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Lymphocyte/Macrophage Interactions |
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237 | (1) |
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Conclusions and Perspectives |
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238 | (8) |
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238 | (8) |
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Development and Differentiation of Neural Stem and Progenitor Cells on Synthetic and Biologically Based Surfaces |
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246 | (1) |
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Neural Stem and Progenitor Cells |
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247 | (2) |
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Synthetic Material Surfaces |
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249 | (4) |
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Nonbiodegradable Substrates |
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249 | (2) |
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Biodegradable Polymer Substrates |
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251 | (2) |
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Biologically Derived Surfaces |
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253 | (6) |
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Poly(L-lysine)-Based Substrates |
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253 | (1) |
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254 | (2) |
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256 | (1) |
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257 | (1) |
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Polysaccharides from Other Sources |
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258 | (1) |
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259 | (5) |
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260 | (4) |
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Toward Osteogenic Differentiation of Marrow Stromal Cells and In Vitro Production of Mineralized Extracellular Matrix onto Natural Scaffolds |
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264 | (1) |
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Scaffolds of Natural Origin - Polysaccharides |
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265 | (3) |
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266 | (1) |
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267 | (1) |
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268 | (1) |
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268 | (3) |
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269 | (1) |
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270 | (1) |
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Incorporation of Biomolecules into CaP Biomimetic Coatings |
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270 | (1) |
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Osteogenic Differentiation of Marrow Stromal Cells and Mineralized ECM Production In Vitro |
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271 | (3) |
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271 | (1) |
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Osteogenic Differentiation |
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272 | (1) |
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Bone-Specific Matrix Proteins |
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273 | (1) |
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274 | (10) |
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275 | (9) |
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Biomimetic Nanophase Materials to Promote New Tissue Formation for Tissue-Engineering Applications |
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284 | (1) |
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Fabrication of Biomimetic Scaffolds with Nanoscale Architecture |
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284 | (4) |
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Nanofibrous Polymeric Scaffolds |
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285 | (1) |
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Nanophase Ceramic Scaffolds |
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286 | (1) |
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286 | (2) |
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Surface Modification of Nanofibrous Scaffolds |
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288 | (4) |
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Surface-Modification Methods for Scaffolds |
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289 | (1) |
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Surface Engineering of Nanofibrous Scaffolds Using Self-Assembly Techniques |
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289 | (2) |
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Porogen-Induced Surface Modification for Nanofibrous Scaffolds |
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291 | (1) |
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Effects of the Nanoarchitecture of Scaffolds on Cell Function and New Tissue Formation |
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292 | (2) |
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292 | (1) |
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293 | (1) |
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Cell Differentiation and Tissue Formation |
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293 | (1) |
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294 | (4) |
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294 | (4) |
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Photofunctionalization of Materials to Promote Protein and Cell Interactions for Tissue-Engineering Applications |
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298 | (1) |
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Mechanisms of Photofunctionalization |
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298 | (3) |
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299 | (2) |
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301 | (1) |
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Photoinitiators in Biomaterials and Tissue Engineering |
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301 | (2) |
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Strategies to Fabricate Photofunctionalized Materials for Biomedical Applications |
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303 | (6) |
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Photopolymerized Biomaterial Scaffolds |
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303 | (2) |
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305 | (2) |
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307 | (2) |
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Photofunctionalized Materials to Promote Cell Interactions for Tissue-Engineering Applications |
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309 | (5) |
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Bone and Cartilage Tissue Engineering |
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310 | (3) |
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Neural Tissue Engineering |
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313 | (1) |
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314 | (6) |
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315 | (5) |
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Hydrogel Nanocomposites in Biology and Medicine: Applications and Interactions |
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320 | (1) |
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Hydrogel Nanocomposites for Drug-Delivery Applications |
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321 | (6) |
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Hydrogel Nanocomposites for Remote-Controlled Drug Release |
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322 | (3) |
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Hydrogel-Clay Nanocomposits for Enhanced Drug-Release Profile |
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325 | (2) |
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Hydrogel Nanocomposites for Tissue-Engineering Applications |
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327 | (7) |
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Hydrogel Nanocomposites for Bone Tissue Engineering |
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327 | (4) |
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Hydrogel Nanocomposites for Articular Cartilage Tissue Engineering |
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331 | (1) |
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Hydrogel Nanocomposites for Cornea Applications |
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332 | (1) |
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Hydrogel Nanocomposites for Cell Adhesion Applications |
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332 | (2) |
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Hydrogel Nanocomposites for Other Therapeutic Applications |
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334 | (3) |
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Antimicrobial Applications |
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334 | (2) |
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Thermal Therapy Applications |
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336 | (1) |
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Hydrogel Nanocomposites and Biological Interactions |
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337 | (1) |
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338 | (6) |
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339 | (5) |
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Protein and Cell Interactions with Nanophase Biomaterrials |
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344 | (1) |
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Protein Interactions with Nanophase Materials |
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344 | (3) |
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345 | (2) |
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Cell Interactions with Nanophase Materials |
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347 | (4) |
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Adhesion of Bone Cells on Nanophase Materials |
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348 | (1) |
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Mechanism of Cell Adhesion on Nanophase Materials |
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349 | (1) |
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Other Functions of Bone Cells on Nanophase Materials |
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350 | (1) |
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Adhesion and Function of Other Cells on Nanophase Materials |
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350 | (1) |
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351 | (5) |
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352 | (4) |
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Inflammatory Response to Implanted Nanostructured Materials |
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356 | (1) |
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357 | (3) |
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357 | (1) |
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357 | (1) |
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358 | (1) |
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359 | (1) |
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Immune Response to Implanted Nanostructured Materials |
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360 | (8) |
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Inflammatory Response to Biomaterials |
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360 | (3) |
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Acute Inflammation and Encapsulation in Response to Nanostructured Biomaterials |
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363 | (5) |
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368 | (6) |
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369 | (5) |
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Collagen I-Coated Titanium Surfaces for Bone Implantation |
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374 | (1) |
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Literature Reports Regarding Collagen-Coated Ti Surfaces |
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375 | (6) |
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In Vitro Studies of Collagen-Coated Ti Surfaces |
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375 | (4) |
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In Vivo Studies on Collagen-Coated Ti Surfaces |
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379 | (2) |
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Design of Collagen-Coated Biomaterial Surfaces |
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381 | (12) |
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Collagen Coatings on Ti Implants: Relevant Parameters |
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381 | (8) |
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Collagen Coating of Ti Implants: Summary |
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389 | (4) |
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393 | (5) |
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394 | (4) |
|
Prevention of Postsurgical Adhesions: A Biomaterials Perspective |
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398 | (1) |
|
Postsurgical Adhesion (PSA) Formation |
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398 | (2) |
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Methods of PSA Prevention and Control |
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400 | (6) |
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Modification of Surgical Technique |
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400 | (1) |
|
Pharmaceutical Interventions |
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401 | (1) |
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402 | (2) |
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404 | (2) |
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406 | (6) |
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412 | (5) |
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|
413 | (4) |
Index |
|
417 | |