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El. knyga: Biomedical Textiles for Orthopaedic and Surgical Applications: Fundamentals, Applications and Tissue Engineering

Edited by (Biomedical Structures Ltd, USA)
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Recent concerns over the possible effects of metal-on-metal orthopaedic implants and the evolution of more natural structures made from fibre have made medical device manufacturers consider the potential of fibre. Textiles offer the potential to replace traditional materials with novel fibres which are more suitable for many load bearing applications. Orthopaedics, in particular, is embracing textile technology for repairing, replacing, and regenerating integral pieces of the skeletal system and its associated components. This important new book will provide readers with a comprehensive overview of the role biomedical textiles can play in the orthopaedic field. Chapters in part one will discuss the fundamentals of textiles for orthopaedic applications. Part two will cover textiles for implantable orthopaedic applications whilst the final set of chapters will discuss the role of textiles in orthopaedic tissue engineering.
  • Provides a comprehensive overview of the role biomedical textiles can play in the orthopaedic field

Daugiau informacijos

A comprehensive overview of the role biomedical textiles can play in orthopaedics, covering such topics as embroidery technology for hard tissue scaffolds, nonwoven scaffolds for bone regeneration, ACL prostheses using biotextiles, and more
List of contributors ix
Woodhead Publishing Series in Biomaterials xi
1 Biomechanical testing and the development of silk-based textiles for regenerative medicine and surgery 1(22)
A. Woods
C. Holland
1.1 Introduction
1(1)
1.2 Current landscape
2(2)
1.3 A new paradigm: Compliance Matching and Material Property Led Engineering Technologies
4(7)
1.4 Complete case study: Rotator cuff tendons
11(3)
1.5 Future trends and applications
14(1)
1.6 Conclusions
15(1)
1.7 Sources of further information and advice
16(1)
Websites
16(1)
Acknowledgements
17(1)
References
17(6)
2 Embroidery technology for hard-tissue scaffolds 23(22)
A.C. Breier
2.1 Introduction
23(4)
2.2 Manufacturing of porous textile structures using embroidery technology
27(8)
2.3 Application of embroidered scaffolds for hard-tissue engineering
35(4)
2.4 Conclusion
39(1)
2.5 Future trends
39(1)
References
40(5)
3 Nonwoven scaffolds for bone regeneration 45(22)
E.R. Durham
G. Tronci
X. Yang
D.J. Wood
S.J. Russell
3.1 The structure of bone and the mechanisms for self-repair
45(2)
3.2 Fibre manufacture from biomaterials
47(6)
3.3 Design and assembly of scaffold architectures
53(4)
3.4 Considerations for surgical implantation of nonwoven scaffolds
57(2)
3.5 Future trends
59(1)
Acknowledgements
60(1)
References
60(7)
4 Bioabsorbable fabrics for musculoskeletal scaffolds 67(24)
Minna Kellomdki
Kaisa Lathe
Ville Tuija Annala
4.1 Introduction
67(1)
4.2 Bioabsorbable materials, fibre spinning and properties, and yarn preparation
67(2)
4.3 Processing technologies for fabrics
69(2)
4.4 Fabric structures and their characteristics
71(6)
4.5 Bone tissue engineering using fabrics
77(1)
4.6 Cartilage tissue engineering using fabrics
78(2)
4.7 Ligament and tendon tissue engineering using fabrics
80(2)
4.8 Tissue-engineered joints
82(1)
4.9 Fabrics commercially available for temporary tissue repair
83(1)
4.10 Future trends
83(2)
References
85(6)
5 Nanofibers for ligament and tendon tissue regeneration 91(28)
Victor Leung
Heejae Yang
Frank Ko
5.1 Introduction
91(1)
5.2 Current treatment and challenges
92(5)
5.3 Nanofiber scaffolds as a new frontier in tissue engineering
97(4)
5.4 Tailored nanofiber scaffolds for tendon and ligament regeneration
101(7)
5.5 Nanofiber assembly into three-dimensional tendon or ligament scaffolds
108(3)
5.6 Conclusion
111(1)
References
112(7)
6 Absorbable, drug-loaded, extruded fiber for implantation 119(26)
Kevin D. Nelson
6.1 Introduction
119(1)
6.2 Materials and fabrication techniques
120(10)
6.3 Drug loading and release
130(6)
6.4 Applications
136(5)
6.5
Chapter summary
141(1)
References
142(3)
7 Anterior cruciate ligament prostheses using biotextiles 145(46)
M. Laflamme
J. Lamontagne
R. Guidoin
7.1 Introduction
145(1)
7.2 Anatomy and structure of the anterior cruciate ligament
145(4)
7.3 Biomechanics of the ACL
149(1)
7.4 Clinical problems associated with the ACL
150(2)
7.5 Diagnosis and treatment of ACL ruptures
152(2)
7.6 Autograft for ACL reconstruction
154(7)
7.7 Allograft for ACL reconstruction
161(1)
7.8 Graft healing in ACL reconstructive surgery
162(2)
7.9 The use of synthetic materials and prostheses in ACL reconstructive surgery
164(6)
7.10 Complications with synthetic ligaments
170(4)
7.11 Augmentation devices
174(1)
7.12 Tissue engineering and scaffolds
175(4)
7.13 Xenografts
179(1)
7.14 Conclusion
180(1)
References
180(11)
Index 191