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Biosynthetic Polymers for Medical Applications [Kietas viršelis]

Edited by (University of New South Wales, Australia), Edited by (University of New South Wales, Australia), Edited by (University of New South Wales, Australia)
  • Formatas: Hardback, 358 pages, aukštis x plotis: 229x152 mm, weight: 500 g
  • Serija: Woodhead Publishing Series in Biomaterials
  • Išleidimo metai: 25-Nov-2015
  • Leidėjas: Woodhead Publishing Ltd
  • ISBN-10: 178242105X
  • ISBN-13: 9781782421054
Kitos knygos pagal šią temą:
Biosynthetic Polymers for Medical ApplicationsDidesnis paveikslėlis
  • Formatas: Hardback, 358 pages, aukštis x plotis: 229x152 mm, weight: 500 g
  • Serija: Woodhead Publishing Series in Biomaterials
  • Išleidimo metai: 25-Nov-2015
  • Leidėjas: Woodhead Publishing Ltd
  • ISBN-10: 178242105X
  • ISBN-13: 9781782421054
Kitos knygos pagal šią temą:
Pastovi nuoroda: https://www.kriso.lt/db/9781782421054.html
Raktažodžiai:

Biosynthetic Polymers for Medical Applications provides the latest information on biopolymers, the polymers that have been produced from living organisms and are biodegradable in nature. These advanced materials are becoming increasingly important for medical applications due to their favorable properties, such as degradability and biocompatibility.

This important book provides readers with a thorough review of the fundamentals of biosynthetic polymers and their applications. Part One covers the fundamentals of biosynthetic polymers for medical applications, while Part Two explores biosynthetic polymer coatings and surface modification. Subsequent sections discuss biosynthetic polymers for tissue engineering applications and how to conduct polymers for medical applications.

  • Comprehensively covers all major medical applications of biosynthetic polymers
  • Provides an overview of non-degradable and biodegradable biosynthetic polymers and their medical uses
  • Presents a specific focus on coatings and surface modifications, biosynthetic hydrogels, particulate systems for gene and drug delivery, and conjugated conducting polymers

Daugiau informacijos

This book provides an exploration of the fundamentals of biosynthetic polymers and the techniques used in their medical applications due to their favorable properties, including degradability and biocompatibility, along with their usage in tissue engineering and the further uses of polymers for other medical applications
List of contributors
ix
Woodhead Publishing Series in Biomaterials xi
Part One Introduction and fundamentals
1(84)
1 Introduction to biomedical polymers and biocompatibility
3(30)
LA. Poole-Warren
A.J. Patton
1.1 Introduction
3(1)
1.2 Natural or biological polymers
4(14)
1.3 Advantages and disadvantages of natural polymers
18(9)
1.4 Biosynthetic polymers
27(1)
1.5 Conclusion
28(5)
References
28(5)
2 Nondegradable synthetic polymers for medical devices and implants
33(30)
P.A. Gunatillake
R. Adhikari
2.1 Introduction
33(1)
2.2 Ultra-high molecular weight poly(ethylene) (UHMWPE)
34(6)
2.3 Polypropylene (PP)
40(2)
2.4 Poly(methyl methacrylate) (PMMA)
42(2)
2.5 Polyurethane (PU)
44(5)
2.6 Poly(dimethyl siloxane) (PDMS)
49(4)
2.7 Polyether ether ketone (PEEK)
53(2)
2.8 Future directions
55(8)
References
56(7)
3 Biodegradable and bioerodible polymers for medical applications
63(22)
K.E. Uhrich
D. Abdelhamid
3.1 Introduction
63(1)
3.2 Concepts and terminology
63(8)
3.3 Motivating factors for using polymer--drug conjugates
71(4)
3.4 Current and future trends
75(10)
Acknowledgments
78(1)
References
78(7)
Part Two Coatings and surface modifications
85(86)
4 Bio-inspired antimicrobial polymers
87(42)
T.D. Michl
K.E.S. Locock
S.S. Griesser
M. Haeussler
L. Meagher
H.J. Griesser
4.1 Introduction
87(2)
4.2 Naturally occurring AMPs
89(8)
4.3 Synthetic polymer mimics of AMPs
97(13)
4.4 Chitosan -- a natural antimicrobial polysaccharide
110(4)
4.5 Neutral polymer brush layers for reducing bacterial attachment
114(15)
References
119(10)
5 Plasma-based surface modification for the control of biointerfacial interactions
129(16)
H. Thissen
5.1 Introduction
129(3)
5.2 Plasma treatment of material surfaces
132(2)
5.3 Plasma polymer-based coatings
134(2)
5.4 Plasma polymer-based interlayers
136(1)
5.5 Plasma polymer-based patterning
137(3)
5.6 Functional plasma polymers
140(1)
5.7 Antimicrobial plasma polymer coatings
141(1)
5.8 Likely future trends
141(1)
5.9 Sources of further information
142(3)
References
142(3)
6 Stent coatings for blood compatibility
145(26)
K. Udipi
6.1 Introduction
145(1)
6.2 Stent development
145(2)
6.3 Thrombosis issue
147(6)
6.4 Drug-eluting stent coatings
153(7)
6.5 Conclusions
160(11)
Acknowledgment
160(1)
References
161(10)
Part Three Biosynthetic hydrogels
171(70)
7 Degradable hydrogel systems for biomedical applications
173(16)
B. Ozcelik
7.1 Introduction
173(1)
7.2 Hydrogel precursors
173(2)
7.3 Desired hydrogel properties
175(1)
7.4 Degradable hydrogel systems
175(9)
7.5 Where to? -- degradable hydrogels
184(5)
References
185(4)
8 Angiogenesis in hydrogel biomaterials
189(16)
B.A. Nsiah
E.M. Moore
L.C. Roudsari
N.K. Virdone
J.L. West
8.1 Introduction
189(1)
8.2 Biology of angiogenesis
189(1)
8.3 Protein hydrogels to support angiogenic activity
190(1)
8.4 Synthetic hydrogels to support angiogenic activity
191(5)
8.5 In vitro culture of vascular networks
196(2)
8.6 Inducing angiogenesis in host tissue
198(1)
8.7 Conclusions
199(6)
References
199(6)
9 Engineering biosynthetic cell encapsulation systems
205(36)
J.J. Roberts
P.J. Martens
9.1 Introduction
205(3)
9.2 Natural polymers
208(8)
9.3 Synthetic polymers
216(5)
9.4 Biosynthetic polymers
221(8)
9.5 Future trends
229(12)
References
229(12)
Part Four Conjugated conducting polymers
241(90)
10 Conducting polymers and their biomedical applications
243(34)
N. Yi
M.R. Abidian
10.1 Introduction
243(1)
10.2 Conducting mechanism
244(1)
10.3 Electrochemical polymerisation of conducting polymers
245(6)
10.4 Applications of conducting polymers in biomedical fields
251(20)
10.5 Conclusions
271(6)
References
271(6)
11 Biosynthetic conductive polymer composites for tissue-engineering biomedical devices
277(22)
R.A. Green
J.A. Goding
11.1 Introduction
277(1)
11.2 Conductive polymer composites
278(8)
11.3 Biological components in CP composites
286(4)
11.4 In vivo application of CP composites
290(3)
11.5 Summary and future directions
293(6)
References
294(5)
12 Degradable conjugated conducting polymers and nerve guidance
299(32)
M. Asplund
12.1 Introduction
299(1)
12.2 Material challenges in neural engineering
300(1)
12.3 Processing of conducting polymers for the generation of 3D scaffolds
300(8)
12.4 Biodegradable conducting polymers
308(5)
12.5 Biomolecular and topographical guidance
313(7)
12.6 Biological performance of CPs for neural regeneration
320(1)
12.7 Future trends and remaining challenges
321(2)
12.8 Sources for further information
323(8)
Abbreviations
324(1)
References
325(6)
Index 331
Professor Poole-Warren was awarded a PhD degree from the University of New South Wales in 1990 and held various appointments at UNSW after joining the academic staff in 1995. These include Associate Dean Research Training and Associate Dean Research in the Faculty of Engineering (2005-2009) and Professor in the Graduate School of Biomedical Engineering (2009). She was appointed Dean of Graduate Research in 2010 and Pro-Vice Chancellor (Research Training) in 2012.Professor Poole-Warren continues to lead a research group in biomedical engineering focusing on design and understanding of biosynthetic polymers for medical applications. Dr Penny Martens is a Senior Lecturer with the Graduate School of Biomedical Engineering. Her research focuses on the use of biosynthetic hydrogels for a variety of biomedical applications, including diabetes treatment, neural electrodes and cartilage repair. Dr Rylie Green is a Research Fellow with the Graduate School of Biomedical Engineering. Dr Greens research has been focused on developing bioactive conducting polymers for application to medical electrodes, with a specific focus on vision prostheses. More recently Dr Green has been exploring hybrids of conducting polymers and hydrogels to reduce strain mismatch with neural tissue and improve long-term cell interactions at the neural interface through drug delivery.