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El. knyga: Cancer Biomarkers

Edited by (Glyfada, Greece)
  • Formatas: 382 pages
  • Išleidimo metai: 19-Nov-2012
  • Leidėjas: Science Publishers,U.S.
  • Kalba: eng
  • ISBN-13: 9781466565531
Kitos knygos pagal šią temą:
  • Formatas: 382 pages
  • Išleidimo metai: 19-Nov-2012
  • Leidėjas: Science Publishers,U.S.
  • Kalba: eng
  • ISBN-13: 9781466565531
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The contributors offer a detailed overview of the emerging field of cancer biomarkers--and illustrate the need for improved and more extensive design and clinical trials. Topics include: improving research on biomarkers for early detection and screening of cancers, urine biomarkers for prostate cancer detection, cellular senescence and cancer development, micro RNAs, and mechanistic aspects of oxidative stress involvement in human environmental and occupational carcinogenesis. The intended audience is upper level students, doctors, researchers, biologists, and others in fields related to cancer diagnosis. Editor is Georgakilas (biology, East Carolina U.). Annotation ©2013 Book News, Inc., Portland, OR (booknews.com)

This unique synthesis of chapters from top experts in their fields, targets the very important and upcoming area of cancer biomarkers and the need for better and more rigorous design and clinical trial. The book covers several aspects of cancer molecular markers from innovation, screening, controversies and future directions. The primary target audience for the book includes PhD and MD students, researchers, biologists, medical doctors and professionals who are interested in mechanistic studies on cancer diagnosis and translational benefits from personalized cancer treatment using the new era of biomarkers.

Preface v
List of Contributors
ix
1 Improving Research on Biomarkers for Early Detection and Screening of Cancers
1(22)
Claire S. Zhu
Paul F. Pinsky
Christine D. Berg
2 Biomarkers of Oxidative Stress in Carcinogenesis
23(28)
Humberto Rodriguez-Rocha
Aracely Garcia-Garcia
Rodrigo Franco
3 β-Catenin: A Novel Biomarker and Therapeutic Target in Liver Cancer
51(26)
Anupam Bishayee
4 Urine Biomarkers for Prostate Cancer Detection
77(24)
Yan-Hua Chen
Art A. Rodriguez
Qun Lu
5 Ectodomain Shedding as a Mechanism to Generate Cancer Biomarkers (Ectomarkers)
101(72)
Maria J. Ruiz-Echevarria
Xiaofei Chen
Ryan F. Overcash
6 The BRCT Signaling `Landscape': Emerging Concepts and Implications in Tumorigenesis and Cancer Diagnostics
173(36)
Dimitris Mastellos
George Nounesis
7 Cellular Senescence and Cancer Development: Antagonistic and Synergistic Relations
209(24)
Dimitris Kletsas
8 MicroRNAs: From Regulators of Gene Expression to Cancer Biomarkers
233(52)
Stamatina Giannouli
Panagiotis Maragozidis
Konstantinos I. Gourgoulianis
Nikolaos A.A. Balatsos
9 Targeting PARP-1 in Breast Cancer: The Paradigm of a DNA Repair-based Therapeutic Strategy
285(36)
Francisco Javier Oliver
Jara Majuelos-Melguizo
Jose Manuel Rodriguez-Vargas
Ariannys Gonzalez-Flores
A. Peralta-Leal
Laura Lopez
Maria Isabel Rodriguez
10 Statins in Prostate Cancer: Prevention and Treatment
321(24)
Khaled Aziz
Phuoc T. Tran
11 Mechanistic Aspects of Oxidative Stress Involvement in Human Environmental and Occupational Carcinogenesis
345(14)
Dominique Ziech
Aglaia Pappa
Mihalis I. Panayiotidis
Index 359(4)
Color Plate Section 363
Georgakilas, Alexandros G