Preface |
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Contributors |
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Part I Background: Epigenetic Mechanism |
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1 Cancer Epigenetics: An Introduction |
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3 | (24) |
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2 Community Resources and Technologies Developed Through the NIH Roadmap Epigenomics Program |
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27 | (24) |
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3 Epigenome-Wide Association Studies (EWAS): Past, Present, and Future |
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51 | (14) |
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4 Epigenetic Biomarkers in Liver Cancer |
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65 | (14) |
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Part II Cancer Specific Type Epigenetic Changes |
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5 Cancer Type-Specific Epigenetic Changes: Gastric Cancer |
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79 | (24) |
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Danielle Queiroz Calcagno |
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Marilia de Arruda Cardoso Smith |
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6 Beyond the Island: Epigenetic Biomarkers of Colorectal and Prostate Cancer |
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103 | (22) |
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7 Prostate Cancer Epigenome |
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125 | (16) |
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8 CpG Island Hypermethylation as a Biomarker for the Early Detection of Lung Cancer |
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141 | (32) |
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9 Analysis of DNA Methylation in Pancreatic Cancer: An Update |
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173 | (10) |
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10 Epigenetics of Urothelial Carcinoma |
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183 | (34) |
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Evangelia A. Koutsogiannouli |
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11 Epigenetics of Prostate Cancer |
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217 | (18) |
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12 Methylation Profile Landscape in Mesothelioma: Possible Implications in Early Detection, Disease Progression, and Therapeutic Options |
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235 | (16) |
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Part III Methods and Technologies Used for Detecting Epigenetic Changes |
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13 Techniques to Access Histone Modifications and Variants in Cancer |
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251 | (22) |
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14 Single Base Resolution Analysis of 5-Methylcytosine and 5-Hydroxymethylcytosine by RRBS and TAB-RRBS |
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273 | (16) |
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15 Quantitative DNA Methylation Analysis for Epigenotyping of Colorectal Cancer |
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289 | (12) |
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16 Histone Modifications Associated with Cancer Cell Migration and Invasion |
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301 | (20) |
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Part IV Factors that Influence Epigenetic Changes in Cancer |
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17 Aberrant Epigenetic Modifications in Radiation-Resistant Head and Neck Cancers |
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321 | (12) |
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18 Cancer-Associated Infectious Agents and Epigenetic Regulation |
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333 | (22) |
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19 Toxicoepigenomics and Cancer: Implications for Screening |
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355 | (14) |
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20 Human Papilloma Virus (HPV) Modulation of the HNSCC Epigenome |
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369 | (12) |
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21 Epigenetic Regulation of HIV, AIDS, and AIDS-Related Malignancies |
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381 | (24) |
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22 Epigenetics of Colorectal Cancer |
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405 | (20) |
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23 Epigenetics in Breast and Prostate Cancer |
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425 | (44) |
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Part V Future Directions: Risk Assessment, Diagnosis, Treatment, and Prognosis |
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469 | (18) |
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25 Use of Epigenetic Modulators as a Powerful Adjuvant for Breast Cancer Therapies |
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487 | (24) |
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26 Epigenetic Approaches in Glioblastoma Multiforme and Their Implication in Screening and Diagnosis |
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511 | (12) |
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27 Detection of Circulatory MicroRNAs in Prostate Cancer |
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523 | (16) |
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28 Identification and Characterization of Small-Molecule Inhibitors of Lysine Acetyltransferases |
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539 | (10) |
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29 Epigenetic Regulation in Biopsychosocial Pathways |
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549 | (20) |
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569 | (28) |
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31 P53 Tumor Suppression Network in Cancer Epigenetics |
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597 | (10) |
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32 Promoter Hypermethylation as a Biomarker in Prostate Adenocarcinoma |
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607 | (20) |
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33 Sequencing the Cancer Methylome |
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627 | (26) |
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34 Global DNA Methylation Profiling Technologies and the Ovarian Cancer Methylome |
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653 | (24) |
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35 Recent Progress in the Discovery of Epigenetic Inhibitors for the Treatment of Cancer |
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677 | (12) |
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36 At the Crossroad Between Obesity and Gastric Cancer |
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689 | (20) |
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37 Detection of Epigenetic Aberrations in the Development of Hepatocellular Carcinoma |
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709 | (24) |
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38 Specific Type Epigenetic Changes in Cervical Cancers |
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733 | (18) |
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39 Epigenetics in Head and Neck Cancer |
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751 | (20) |
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40 Epigenetic Therapy for Colorectal Cancer |
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771 | (12) |
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41 Epigenetics of Gastric Cancer |
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783 | (18) |
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Index |
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