Atnaujinkite slapukų nuostatas

El. knyga: Cancer Prevention and Management through Exercise and Weight Control

Edited by (Harvard University, BIDMC, Boston, Massachusetts, USA)
  • Formatas: 608 pages
  • Išleidimo metai: 19-Apr-2016
  • Leidėjas: CRC Press Inc
  • Kalba: eng
  • ISBN-13: 9781420026641
  • Formatas: 608 pages
  • Išleidimo metai: 19-Apr-2016
  • Leidėjas: CRC Press Inc
  • Kalba: eng
  • ISBN-13: 9781420026641

DRM apribojimai

  • Kopijuoti:

    neleidžiama

  • Spausdinti:

    neleidžiama

  • El. knygos naudojimas:

    Skaitmeninių teisių valdymas (DRM)
    Leidykla pateikė šią knygą šifruota forma, o tai reiškia, kad norint ją atrakinti ir perskaityti reikia įdiegti nemokamą programinę įrangą. Norint skaityti šią el. knygą, turite susikurti Adobe ID . Daugiau informacijos  čia. El. knygą galima atsisiųsti į 6 įrenginius (vienas vartotojas su tuo pačiu Adobe ID).

    Reikalinga programinė įranga
    Norint skaityti šią el. knygą mobiliajame įrenginyje (telefone ar planšetiniame kompiuteryje), turite įdiegti šią nemokamą programėlę: PocketBook Reader (iOS / Android)

    Norint skaityti šią el. knygą asmeniniame arba „Mac“ kompiuteryje, Jums reikalinga  Adobe Digital Editions “ (tai nemokama programa, specialiai sukurta el. knygoms. Tai nėra tas pats, kas „Adobe Reader“, kurią tikriausiai jau turite savo kompiuteryje.)

    Negalite skaityti šios el. knygos naudodami „Amazon Kindle“.

..it is increasingly clear that cancer is also a disease of inertia. In this book, a broadly multidisciplinary group presents the evidence and provides the recommendations. The antidote to diseases of inertia is movement lets move!

John Potter, M.D.,Ph.D., from the Foreword

The American Cancer Society estimates that a third of all cancer deaths could be prevented through avoidance of obesity and the rejection of sedentary lifestyles. The World Health Organization also supports this claim. Additionally, these and other organizations now recognize the role that activity can play in improving the quality of life for cancer patients.

Cancer Prevention and Management through Exercise and Weight Control provides us with the support necessary to make a call to action. Itbrings together the contributions of world-class researchers to lay out the evidence and a plan of attack for coping with this crisis. The text begins by focusing on the research methods used in assessing the complex associations between activity, energy balance, and risk and prognosis. In comprehensive literature reviews, the authors consider the role of physical activity in the incidence of individual cancers, then explore the mechanisms that might explain this connection. They continue with a look at the relation between weight and cancer incidence, including a consideration of genetics.

Research is also provided linking physical activity and weight control to a cancer patients quality of life and prognosis. The work concludes with ideas on how a plan of action might be implemented at the individual, clinical, and public health levels. It also provides guidance on incorporating exercise and diet recommendations into clinical oncology practice.

Recenzijos

This volume is one of the only of its kind dedicated to helping healthcare providers establish a concrete plan allowing patients to control weight gain through exercise in order to forestall cancer. Expert researchers do an outstanding job delineating this material within a logical framework, looking at ways that physical activity impacts the incidence of cancer in the breast, prostate and colorectal regions it promotes a step away from drug-based therapies in favor of a more holistic approach to mitigating cancer risks. Bluntly, its a message [ to] those practicing medicine in the Western world should pay close and careful attention to. Recommended to all primary care physicians (in addition to dieticians and nurse practitioners) who serve as a patients first-line of defense against disease. In addition, this volume is highly recommended to all Health Science libraries because of its well-detailed and erudite examination of the influence physical activity has on the processes of cancer. John Aiello, in The Electric Review

is a collection of 35 chapters organized into 8 sections, each covering different aspects of the complex relationships among body weight, physical activity, cancer incidence, and cancer prognosis. Each chapter provides a short review and summary of research studies that have addressed a variety of methodological, epidemiological, experimental, and clinical issues related to the prevention and management of different cancers through physical activity and body-weight management. The organization of the chapters into section is logical, and each chapter includes a list of contents at the beginning. would be of value to any clinicians who works with patients who have cancer and those who have survived it. It would be an especially helpful resource to anyone who wants to learn more about the current state of knowledge in the relatively new linkage of cancer management, obesity, genetics, and physical activity. Anthony E. Kincaid, Associate Professor, Department of Physical Therapy, Creighton University, Nebraska, in Physical Therapy, Vol. 87, No. 5, p. 615, May 2007

The present volume is not a rehash of some long-past symposium. Rather, it contains 35 invited contributions, each with 50-200 references. In all, this text provides a very thorough, evidence-based summary of current knowledge in a rapidly growing area of research, and it will be an important resource for those working on exercise, obesity and cancer. Roy J. Shephard in Canadian Journal of Applied Physiology, June 2007

"The research presented in McTiernans text is truly ground-breaking Bluntly, its a message those practicing medicine in the Western world should pay close and careful attention to Recommended to all primary care physicians (in addition to dieticians and nurse practitioners) who serve as a patients first-line of defense against disease. In addition, this volume is highly recommended to all Health Science libraries because of its well-detailed and erudite examination of the influence physical activity has on the processes of cancer."

--The Electric Review

SECTION I Research Methods
Observational Studies and Intervention Trials in Exercise, Diet, and Cancer Prevention Research
3(10)
Ross L. Prentice
Introduction
3(1)
Observational Studies of Physical Activity and Dietary Patterns
4(3)
Confounding
4(1)
``Exposure'' Assessment Measurement Error
4(2)
Observational Study Reliability
6(1)
Intervention Trials of Physical Activity and Nutrition
7(1)
Intervention Trial Features and Challenges
7(1)
Intermediate Outcome Trials
7(1)
Sources of Hypotheses and Interventions
8(1)
Research Needs and Agenda
8(1)
Methodology Development
8(1)
Hypothesis Development and Initial Testing
9(1)
Generation and Evaluation of Full-Scale Trial Proposals
9(1)
Acknowledgments
9(1)
References
9(4)
Physical Activity Measurement
13(12)
Barbara E. Ainsworth
Karen J. Coleman
Overview
13(1)
Conceptual Framework
14(1)
Direct Physical Activity Assessment Methods
14(2)
Activity Monitors/Motion Sensors
14(1)
Direct Observation
15(1)
Physical Activity Records
16(1)
Physical Activity Logs
16(1)
Indirect Physical Activity Assessment Methods
16(3)
Physical Activity Questionnaires
16(1)
Global Questionnaires
17(1)
Self-Administered Recall Questionnaires
17(1)
Interview-Administered Physical Activity Recall Questionnaires
17(1)
Quantitative History Questionnaires
18(1)
Qualitative Physical Activity Assessment
19(1)
When to Use Physical Activity Assessment Methods
19(1)
Conclusions
20(1)
References
20(5)
Measurement of Body Fat and Energy Balance
25(24)
Melinda Irwin
Introduction
25(1)
Laboratory Methods
26(7)
Densitometry
27(1)
Hydrodensitometry (Underwater Weighing)
27(1)
Air Displacement Plethysmography
28(1)
Imaging Techniques
29(1)
DEXA
29(2)
Computed Tomography (CT)
31(1)
Magnetic Resonance Imaging (MRI)
32(1)
Ultrasound
33(1)
Field Methods
33(5)
Body Mass Index
34(1)
Circumferences
35(1)
Skinfolds
36(1)
Bioelectrical Impedance
37(1)
Energy Balance
38(2)
Summary
40(1)
References
41(8)
SECTION II Physical Activity and Cancer Incidence
Physical Activity and Cancer Incidence: Breast Cancer
49(26)
Alpa V. Patel
Leslie Bernstein
Biological Mechanisms
49(2)
Physical Activity and Estrogen
49(1)
Physical Activity and Insulin Sensitivity
50(1)
Physical Activity and Immune Function
51(1)
Physical Activity, Energy Balance, and Weight Control
51(1)
Previous Literature
51(18)
Recreational Physical Activity
51(1)
Quality of Data on Physical Activity
52(16)
Occupational Physical Activity
68(1)
Confounding and Effect Modification
68(1)
Conclusions
69(1)
References
69(6)
Physical Activity and Colorectal Cancer
75(16)
Martha L. Slattery
Measuring Physical Activity
75(1)
Colorectal Cancer Site-Specific Associations
76(6)
Colon Cancer
76(6)
Rectal Cancer
82(1)
Biological Mechanisms
82(2)
Energy Balance
82(1)
Other Hypothesized Biological Mechanisms
83(1)
Tumor Mutations and Physical Activity
84(1)
Public Health Issues: Dose--Response and Intensity
84(1)
Summary
85(2)
References
87(4)
Physical Activity and Prostate Cancer Risk
91(30)
Christine M. Friedenreich
Introduction
91(1)
Methods
92(1)
Epidemiologic Studies of Physical Activity and Prostate Cancer
92(14)
Overall Results
93(12)
Population Subgroup Results
105(1)
Physical Fitness and Prostate Cancer Risk
106(1)
Biological Mechanisms
106(2)
Methodological Issues
108(3)
Outcome Misclassification
108(1)
Exposure Assessment
109(1)
Confounding and Effect Modification
110(1)
Directions for Future Research
111(1)
Conclusion
112(1)
Acknowledgments
112(1)
References
112(9)
SECTION III Mechanisms Associating Physical Activity with Cancer Incidence
Physical Activity Effects on Sex Hormones
121(10)
Anne McTiernan
Introduction
121(1)
Premenopausal Women
122(2)
Observational Data
122(1)
Intervention Data
122(2)
Postmenopausal Women
124(3)
Observational Data
124(1)
Intervention Data
124(3)
Men
127(1)
Observational Data
127(1)
Intervention Data
127(1)
Intervention Studies of Physical Activity in Cancer Patients
127(1)
Summary
127(1)
References
128(3)
Exercise and Insulin Resistance
131(26)
Laura Lewis Frank
Introduction
131(1)
Physical Activity and Chronic Diseases
132(2)
Overweight and Obesity
132(1)
Type-2 Diabetes Mellitus
133(1)
Exercise and Underlying Mechanisms for Improvement of Insulin Resistance
134(1)
The Effects of Exercise Training
135(2)
Exercise, Central Obesity, and Disease Risk
137(1)
Role of Aerobic Exercise in Glucose Homeostasis: Evidence from Controlled Trials
138(6)
Role of Resistance Exercise in Glucose Homeostasis: Evidence from Randomized-Controlled Trials
144(2)
Lifestyle Interventions (Diet Plus Exercise) and Glucose Homeostasis
146(1)
Summary
147(1)
References
147(10)
Mechanisms Associating Physical Activity with Cancer Incidence: Exercise and Immune Function
157(20)
Catherine M. Wetmore
Cornelia M. Ulrich
Introduction
157(1)
Overview of the Immune System
158(1)
Immune Function and Cancer Development
158(1)
Measures of Immune Function
159(1)
Immunomodulatory Effects of Regular Moderate-Intensity Physical Activity
160(1)
Exercise Effects on Natural Killer Cell Activity and Lymphocyte Proliferation
161(6)
Exercise and Enumeration and Phenotyping of Immune Cells
167(1)
Exercise Effects on Markers of Inflammation
168(1)
Exercise Effects on Antibody Concentrations
169(1)
Exercise Effects on Clinical Manifestations of Immune Function
169(1)
Conclusion
169(1)
References
170(7)
Mechanisms Associating Physical Activity with Cancer Incidence: Exercise and Prostaglandins
177(6)
Maria Elena Martinez
Physical Activity and Colon Cancer
177(1)
Prostaglandins and Colon Cancer
177(1)
Studies Linking Physical Activity, PGE2, and Colon Cancer
178(2)
Summary and Future Directions
180(1)
References
180(3)
Mechanisms Associating Physical Activity with Cancer Incidence: Animal Models
183(16)
Lisa H. Colbert
Introduction
183(1)
Framework for Identifying Mechanisms
184(1)
Oxidative Stress
185(1)
Body Weight/Obesity/Energy Balance
185(5)
Reproductive Hormones
190(1)
Immune Function
191(1)
IGF-1
192(1)
Tissue Size/Morphology
193(1)
Summary
193(1)
References
194(5)
Physical Activity Intervention Studies in Humans
199(10)
Anne McTiernan
Introduction
199(1)
Unique Aspects of Physical Activity Intervention Studies Pertaining to Cancer Prevention
200(1)
Previous Exercise Intervention Studies Relevant to Cancer
200(1)
Human Exercise Intervention Studies Focused on Relevance to Cancer Prevention
201(4)
Exercise Effect on Sex Hormones in Postmenopausal Women (Physical Activity for Total Health Study)
201(2)
Exercise Effect on Colorectal Cell Proliferation and Apoptosis (The APPEAL Study)
203(1)
The ALPHA Trial
204(1)
The Nutrition and Exercise for Women (NEW) Trial
205(1)
Future Research Needs
205(1)
Summary
205(1)
References
206(3)
Genetics, Physical Activity, and Cancer
209(10)
Tuomo Rankinen
Introduction
209(1)
Interindividual Differences in Responsiveness to Exercise Training
209(1)
Genetics and Heterogeneity in Exercise Responsiveness
210(1)
Molecular Genetics
211(1)
Candidate Gene Studies
211(1)
Genotype--Physical Activity Interactions
212(1)
Gene--Physical Activity Interactions and Cancer
213(1)
Conclusions
214(1)
References
214(5)
SECTION IV Overweight/Obesity and Cancer Incidence
Obesity, Weight Change, and Breast Cancer Incidence
219(14)
Rachel Ballard-Barbash
Introduction
219(1)
Birth and Early Childhood Measures
220(1)
Young Adult Measures
220(1)
Adulthood Measures
221(4)
Weight or BMI Measures
221(1)
Waist Circumference or Other Measures of Body Fat Distribution
222(2)
Adult Weight Gain
224(1)
Other Modifying Factors
224(1)
Race/Ethnicity
224(1)
Physical Activity
225(1)
Future Research Directions
225(1)
Conclusions and Population-Attributable Risk
226(2)
References
228(5)
Body Size, Obesity, and Colorectal Cancer
233(12)
Anne McTiernan
Martha L. Slattery
Introduction
233(1)
Colon Cancer
234(2)
Rectal Cancer
236(1)
Adenomas
236(1)
Interactions
236(2)
Tumor Mutations
238(1)
Biological Mechanisms
238(2)
Summary
240(1)
References
240(5)
Endogenous Hormone Metabolism and Endometrial Cancer
245(12)
Rudolf Kaaks
Annekatrin Lukanova
Introduction
245(1)
The Unopposed Estrogen Hypothesis
246(1)
Excess Weight, Bioavailable Estrogens, and Endometrial Cancer Risk
246(1)
Excess Weight, Ovarian Hyperandrogenism, and Endometrial Cancer Risk
247(1)
Chronic Hyperinsulinemia and Endometrial Cancer Risk
248(1)
Summary
249(1)
References
249(8)
Obesity and Pancreatic Cancer
257(12)
Dominique S. Michaud
Edward Giovannucci
Introduction
257(1)
In Vitro and Animal Studies
258(1)
Limitations of Study Designs in Epidemiological Studies
259(1)
Case-Control Studies
259(3)
Cohort Studies
262(1)
Obesity Cohort Studies
263(1)
Meta-Analysis
263(1)
Summary
264(1)
References
264(5)
Obesity and Overweight in Relation to Adenocarcinoma of the Esophagus
269(20)
Cathrine Hoyo
Marilie D. Gammon
Introduction
269(1)
Methods
270(1)
Results
271(6)
Esophageal Adenocarcinoma
271(3)
Gastric Cardia Adenocarcinoma
274(1)
Barrett's Metaplasia
275(2)
Gastroesophageal Reflux Disease (GERD)
277(1)
Discussion
277(4)
Summary and Future Directions
281(1)
References
282(7)
SECTION V Mechanisms Associating Obesity with Cancer Incidence
Obesity and Sex Hormones
289(12)
Rudolf Kaaks
Anne McTiernan
Introduction
289(1)
Adipose Tissue
289(1)
Sex Hormones and Cancer
290(1)
Estrogens
291(3)
Adiposity and Estrogens in Women
291(3)
Adiposity and Estrogens in Men
294(1)
Mechanisms of Adiposity Effect on Sex Steroid Synthesis and Bioavailability
294(1)
Androgens
294(2)
Adiposity and Androgens in Women
294(2)
Adiposity and Androgens in Men
296(1)
Summary
296(1)
References
297(4)
Obesity and Insulin Resistance
301(16)
George Blackburn
Belinda Waltman
Introduction
301(1)
Food Intake and Physical Inactivity: Weight Gain, Obesity, and the Metabolic Syndrome
302(1)
Insulin Resistance Pathophysiology
303(1)
Adipocytes
303(1)
Fatty Acids
304(1)
Cytokines
304(1)
Insulin Resistance and Cancer: Proposed Mechanisms
304(3)
Breast Cancer and Insulin Resistance
305(1)
Obesity and Breast Cancer
305(2)
The Women's Intervention Nutrition Study (WINS)
307(1)
The Women's Health Initiative (WHI)
308(1)
Food Intake Measurement Tools
309(1)
The Prudent Dietary Pattern as Intervention Strategy for Obese, Insulin-Resistant Individuals
309(1)
Summary
309(1)
Acknowledgments
310(1)
References
310(7)
Obesity, Cytokines, and Other Inflammatory Markers
317(12)
Elisa L. Priest
Timothy S. Church
Background
317(3)
Acute and Chronic Inflammation
317(1)
Cytokines
318(1)
Common Markers of Inflammation
318(2)
Adipose Tissue as an Endocrine Organ
320(1)
Research on Obesity and Inflammation
320(1)
Cross-Sectional and Observational Studies
316(5)
Intervention Studies
321(1)
The Interaction of Fitness and Fatness
321(3)
Summary
324(1)
References
324(5)
Mechanisms Associating Obesity with Cancer Incidence: Animal Models
329(12)
Henry J. Thompson
Weiqin Jiang
Zongjian Zhu
Introduction
329(1)
Obesity and Cancer Incidence
330(1)
Positive Energy Balance and Cancer
330(1)
Cellular Processes and Carcinogenesis
331(1)
Cell Proliferation
331(2)
Apoptosis
333(1)
Vascularization
333(1)
Underlying Mechanisms
334(1)
Systemically Driven Mechanisms
334(2)
Insulin and Insulin-Like Growth Factors (IGFs)
334(1)
Adrenal Cortical Steroids
335(1)
Intracellular Mechanisms
336(1)
Final Comments
336(1)
Summary
337(1)
Acknowledgments
337(1)
References
337(4)
Genetics, Obesity, and Cancer
341(16)
Shelley Tworoger
Monica McGrath
Introduction
341(1)
Genetic Contributions to Obesity
341(2)
Heritability of Obesity
341(2)
Interaction between Genetics and the Environment
343(1)
Genetic Variability and Obesity
343(6)
Animal Studies of Obesity
343(1)
Monogenic Forms of Obesity
344(1)
Identifying Genetic Components of Polygenic Obesity
345(1)
Specific Genetic Polymorphisms of Interest
346(2)
Challenges in Identifying Obesity-Related Genes
348(1)
Gene--Gene Interactions
349(1)
Genetic Variability and Lifestyle Interventions to Reduce Obesity and Cancer Risk
349(1)
Conclusions
350(1)
References
351(6)
SECTION VI Physical Activity and Cancer Prognosis
Quality of Life and Fatigue in Breast Cancer
357(10)
Kerri Winters-Stone
Anna L. Schwartz
QOL Measurement in Cancer
357(1)
Effect of Breast Cancer and Treatment on QOL
358(1)
Cancer Treatment-Related Fatigue
359(1)
How Exercise May Improve QOL and Reduce Fatigue in Breast Cancer
359(1)
Evidence for Exercise Effects on QOL and Fatigue in Breast Cancer
359(3)
Cross-Sectional Studies
359(1)
Quasiexperimental Studies
360(1)
Randomized Controlled Trials
361(1)
Summary
362(1)
Future Directions
363(1)
References
364(3)
Exercise and Quality of Life in Survivors of Cancer Other Than Breast
367(20)
Kerry S. Courneya
Kristin L. Campbell
Kristina H. Karvinen
Aliya B. Ladha
Nonbreast Cancer Incidence and Survival Rates
367(1)
Medical Treatments for Cancer
368(1)
Quality of Life in Cancer Survivors
369(1)
Exercise and Quality of Life in Cancer Survivors
370(1)
Studies Involving Mixed Site Cancer Survivors
371(4)
Studies Involving Single Site Cancer Survivors
375(6)
Mechanisms of Enhanced Quality of Life from Exercise in Cancer Survivors
381(1)
Future Research Directions
381(2)
Summary
383(1)
Acknowledgments
383(1)
References
383(4)
Physical Activity and Physiological Effects Relevant to Prognosis
387(18)
Page E. Abrahamson
Marilie D. Gammon
Introduction
387(1)
Methods
388(1)
Results
388(12)
Studies of Physical Activity and Prognosis among Cancer Survivors
388(2)
Studies of Physical Activity and Risk of Cancer Mortality among Noncancer Cohorts
390(6)
Prevalence of Physical Activity among Cancer Survivors
396(4)
Future Directions
400(1)
References
401(4)
SECTION VII Energy Balance and Cancer Prognosis
Energy Balance and Cancer Prognosis, Breast Cancer
405(32)
Pamela J. Goodwin
Introduction
405(1)
Obesity and Breast Cancer Prognosis
406(18)
Weight Gain after Breast Cancer Diagnosis
424(2)
Pathophysiology of Adverse Prognostic Effects of Obesity
426(2)
Conclusions
428(1)
References
429(8)
Energy Balance and Cancer Prognosis: Colon, Prostate, and Other Cancers
437(10)
Cheryl L. Rock
Introduction
437(1)
Colon and Rectal Cancer
438(1)
Prostate Cancer
439(1)
Gynecological Cancers
439(2)
Ovarian Cancer
439(1)
Endometrial Cancer
440(1)
Cervical Cancer
440(1)
Vulvar Cancer
441(1)
Other Cancers
441(1)
Summary and Conclusions
442(1)
References
442(5)
SECTION VIII Implementation
Physical Activity and Energy Balance
447(24)
Mikael Fogelholm
Components of Daily Energy Expenditure
447(5)
Basal Energy Expenditure
448(1)
Diet-Induced Thermogenesis
449(1)
Physical Activity --- Definitions and Classifications
449(3)
Intensity of Physical Activity and Use of Energy Substrates
452(2)
Physical Activity and Weight Management
454(5)
Physical Activity and Primary Prevention of Weight Gain
454(1)
Physical Activity during Weight Reduction
455(2)
Physical Activity and Maintenance of Reduced Body Weight
457(2)
Physical Activity and Metabolic Health
459(2)
Recommendation for Physical Activity and Exercise
461(2)
How Much Physical Activity Is Efficacious for Management of Obesity?
461(1)
What Is a Sustainable Prescription?
462(1)
Is Moderate Physical Activity Enough for Management of Obesity?
462(1)
What Kind of Support and Monitoring Is Needed?
462(1)
Conclusions and Recommendations
463(2)
References
465(6)
Diet and Other Means of Energy Balance Control
471(16)
David Heber
Susan Bowerman
Introduction
471(1)
Understanding Epidemiological Evidence
472(1)
Dietary Factors Affecting Energy Balance
472(9)
Protein Intake Effects on Body Composition and Satiety
472(1)
Fiber Intake Effects on Satiety
473(1)
Total Fruit and Vegetable Intake
474(1)
Glycemic Index and Glycemic Load of the Diet
475(2)
Effects of Dietary Fat on Calorie Balance and Inflammation
477(1)
Meal Replacements and Portion-Controlled Meals
478(1)
Dietary Supplements that Affect Energy Expenditure
479(1)
Caffeine
479(1)
Green Tea Catechins
480(1)
Capsaicin
480(1)
Conclusion
481(1)
References
481(6)
Population-Based Approaches to Increasing Physical Activity
487(14)
Fiona Bull
Introduction
487(1)
What Is a Population Health Approach?
488(1)
Principles of a Population-Based Approach
489(1)
Case for a Population-Based Approach to Physical Activity for Prevention of Site-Specific Cancers
489(1)
Population Levels of Physical Activity
490(1)
Population-Based Interventions --- What Works for Physical Inactivity?
491(2)
National Physical Activity Policy
493(1)
Creating Supportive Environments
493(1)
Case Studies of Population-Based Approach to Physical Activity
494(1)
Conclusion
495(2)
References
497(4)
Incorporating Exercise and Diet Recommendations into Primary Care Practice
501(16)
Nicolaas P. Pronk
Introduction
501(1)
The Magnitude of Obesity
502(1)
The Clinical Burden of Obesity
502(3)
Obesity and Medical Conditions
503(1)
Obesity, Physical Activity, Utilization, and Costs
503(1)
Reduction of the Clinical Burden by Weight Loss and Physical Activity
504(1)
Role of Clinicians in Addressing Obesity, Diet, and Physical Activity
505(2)
Physician Counseling for Obesity and Physical Activity
505(1)
Multiple Risk Factors in Primary Care
506(1)
The Patient-Centered View
507(3)
Translating What We Know into What We Do
510(2)
Extending the Clinical Care Team
511(1)
Connecting the Dots
511(1)
A Protocol to Integrate ``in-Clinic'' and ``between-Clinic'' Visits
512(1)
Summary
512(2)
Acknowledgments
514(1)
References
514(3)
Promoting Physical Activity in Cancer Survivors
517(8)
Anna L. Schwartz
Kerri Winters-Stone
Physical Activity, Motivation, and Noncompliance
517(1)
Patient Interactions
518(1)
Approach to Exercise Prescription
519(1)
Promoting Survivor's Commitment to Exercise
519(1)
Goal Setting and Feedback
520(1)
Adherence Rates in Research Studies
521(1)
Summary
521(1)
References
521(4)
Obesity and Early Stage Breast Cancer Outcome
525(10)
Rowan T. Chlebowski
Michelle L. Geller
Body Weight and Breast Cancer Outcome (Cohorts)
525(1)
Body Weight and Breast Cancer Outcome (in Cooperative Group Trials)
526(1)
Clinical Significance: Obesity in Breast Cancer Patients
527(1)
Obesity and Breast Cancer Patient Outcomes: Potential Mediating Mechanism
527(1)
Race/Ethnicity Obesity and Breast Cancer Outcome
528(1)
Obesity and Breast Cancer Outcome: Potential Intervention Strategies
529(1)
Incorporating Exercise and Diet Recommendations into Clinical Oncology Practice
530(1)
Diet
530(1)
Alcohol Intake
530(1)
Soy Products
531(1)
Exercise
531(1)
References
531(4)
Incorporating Weight Control into Management of Patients with Early Breast Cancer in the U.K.
535(26)
Michelle Harvie
Anthony Howell
Trends in Incidence of and Mortality from Breast Cancer in the U.K.
536(1)
Prevalence of Overweight and Obesity in Cancer Patients in the U.K.
536(2)
Significance of Excess Weight and Weight in Breast Cancer Patients
538(1)
Prevalence of Obesity-Related Comorbidities in Breast Cancer Patients
539(1)
Weight Gain after Diagnosis for Early Breast Cancer
539(2)
Patients Receiving Adjuvant Chemotherapy
539(1)
Women Receiving Neoadjuvant Chemotherapy
540(1)
Women Receiving Adjuvant Endocrine Therapy
540(1)
Subgroups of Early Breast Cancer Patients in which Weight Management May Be Important
541(2)
British South Asian women
541(1)
Women from Lower Social Classes
542(1)
Patients Who Stop Smoking
543(1)
Overweight Patients with Lymphedema
543(1)
Current Practice and Attitudes to Weight Management of Breast Cancer Patients among Health Care Professionals in U.K. Cancer Centers
543(3)
Exercise Interventions in the U.K.
546(1)
Clinical Practice in the U.K. --- Audit of a Weight Loss Service for Breast Cancer Patients
547(1)
Information Needs of Cancer Patients
547(2)
Current Research Programs within the U.K.
549(2)
Guidelines for Weight Management in Early Breast Cancer Patients
551(6)
NICE Guidelines for Best Clinical Practice
551(1)
Recommended Guidelines for Weight Management in Early Breast Cancer
551(1)
During Chemotherapy or Radiotherapy and Endocrine Therapy
552(1)
Recovery Phase
552(1)
Health Maintenance
552(1)
Assessment of Body Weight and Body Composition in Breast Cancer Patients
553(1)
Identifying Patients Suitable for Weight Loss Interventions
553(1)
Patients
553(1)
Motivation for and Barriers to Success for Successful Weight Loss
553(1)
Weight Management Advice
554(1)
Need for an Individualized Approach
554(1)
Goal Setting
554(1)
Weight Loss Advice
554(1)
Factors to Promote Adherence to Weight Loss Program
554(1)
Self-Monitoring
554(1)
Self-Management
554(1)
One-to-One vs. Group Counseling --- Hospital Based
555(1)
Slimming on Prescription
555(1)
Specialist Multidisciplinary Oncology Teams
555(1)
Pharmacotherapy for Weight Management
556(1)
Exercise on Prescription
557(1)
Future Research Priorities
557(1)
References
557(4)
Index 561


Anne McTiernan, M.D., Ph.D., is a faculty member in the Division of Public Health Sciences at the Fred Hutchinson Cancer Research Center in Seattle, Washington, and a research professor in the University of Washington Schools of Medicine and Public Health and Community Medicine.