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Cannabinoids and the Brain 2008 ed. [Kietas viršelis]

Edited by
  • Formatas: Hardback, 583 pages, aukštis x plotis: 235x155 mm, weight: 1058 g, XV, 583 p., 1 Hardback
  • Išleidimo metai: 01-Apr-2008
  • Leidėjas: Springer-Verlag New York Inc.
  • ISBN-10: 0387743480
  • ISBN-13: 9780387743486
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 583 pages, aukštis x plotis: 235x155 mm, weight: 1058 g, XV, 583 p., 1 Hardback
  • Išleidimo metai: 01-Apr-2008
  • Leidėjas: Springer-Verlag New York Inc.
  • ISBN-10: 0387743480
  • ISBN-13: 9780387743486
Kitos knygos pagal šią temą:
Endocannabinoids control most of the body functions, and in the brain, they modulate neurotransmission, synaptic plasticity, confer neuroprotection, control metabolism, neuro- and neuritogenesis, survival, cognitive and motor functions as well as a plethora of other higher-order brain functions. Their fruitful therapeutic potential is recognized by cannabinoid researchers and pharmaceutical companies, respectively.



The aim of this book is to help clinicians, neuroscientists, as well as students, understand the significance of the endocannabinoid system. This book, however, also will be very useful to those who already feel comfortable with the neuroscience of endocannabinoids. The book will introduce the reader to the up-to-date neurobiology of endocannabinoids and related systems, and will detail their pathophysiological role and therapeutic potential. Authors involved in clinical investigations present results of recent clinical trials, and the development of new therapeutic strategies and medicines.
Editorial v
Contributors xiii
Part I Molecular Biology, Pharmacology, Anatomy, and Physiology of the Endocannabinoid and Related Lipidergic Signaling Systems in the Brain
An Historical Introduction to the Endocannabinoid and Endovanilloid Systems
3(12)
Istvan Nagy
John P.M. White
Cleoper C. Paule
Attila Kofalvi
Biosynthesis of Anandamide and 2-Arachidonoylglycerol
15(16)
Takayuki Sugiura
Removal of Endocannabinoids by the Body: Mechanisms and Therapeutic Possibilities
31(16)
Christopher J. Fowler
Lina Thors
Other Cannabimimetic Lipid Signaling Molecules
47(12)
Heather B. Bradshaw
CB1 Cannabinoid Receptors: Molecular Biology, Second Messenger Coupling and Polarized Trafficking in Neurons
59(16)
Andrew J. Irving
Neil McDonald
Tibor Harkany
CB2 Cannabinoid Receptors: Molecular, Signaling, and Trafficking Properties
75(16)
Paul L. Prather
CB1 and CB2 Receptor Pharmacology
91(10)
Roger G. Pertwee
Functional Molecular Biology of the TRPV1 Ion Channel
101(30)
Istvan Nagy
John P.M. White
Cleoper C. Paule
Mervyn Maze
Laszlo Urban
Alternative Interacting Sites and Novel Receptors for Cannabinoid Ligands
131(30)
Attila Kofalvi
Anatomical Distribution of Receptors, Ligands and Enzymes in the Brain and in the Spinal Cord: Circuitries and Neurochemistry
161(42)
Giovanni Marsicano
Rohini Kuner
Endocannabinoids at the Synapse: Retrograde Signaling and Presynaptic Plasticity in the Brain
203(34)
Gregory L. Gerdeman
Endocannabinoid Functions in Neurogenesis, Neuronal Migration, and Specification
237(22)
Tibor Harkany
Manuel Guzman
Yasmin L. Hurd
Part II The Endocannabinoid System in Clinical Neuroscience and Experimental Neuropsychiatry
Cannabinoids in the Management of Nausea and Vomiting
259(18)
Linda A. Parker
Cheryl L. Limebeer
Endocannabinoids in Energy Homeostasis and Metabolic Disorders
277(40)
Isabel Matias
Vincenzo Di Marzo
Attila Kofalvi
Cannabinoids and Neuroprotection
317(14)
Veronica A. Campbell
Eric J. Downer
Neuroinflamination and the Glial Endocannabinoid System
331(30)
Cristina Benito
Rosa Maria Tolon
Estefania Nunez
Maria Ruth Pazos
Julian Romero
Targeting Cannabinoid Receptors in Brain Tumors
361(14)
Guillermo Velasco
Arkaitz Carracedo
Cristina Blazquez
Mar Lorente
Tania Aguado
Cristina Sanchez
Ismael Galve-Roperh
Manuel Guzman
Cannabinoids for the Control of Multiple Sclerosis
375(20)
Gareth Pryce
Sam J. Jackson
David Baker
Endocannabinoids in Alzheimer's Disease
395(12)
Maria L. de Ceballos
The Endocannabinoid System as a Therapeutic Target in Epilepsy
407(16)
Krisztina Monory
Beat Lutz
The Endocannabinoid System in the Physiology and Pathology of the Basal Ganglia
423(62)
Gregory L. Gerdeman
Javier Fernandez-Ruiz
The Endocannabinoid System is a Major Player in Schizophrenia
485(44)
Attila Kofalvi
Markus Fritzsche
The Cannabinoid Controversy: Cannabinoid Agonists and Antagonists as Potential Novel Therapies for Mood Disorders
529(30)
Eleni T. Tzavara
Jeffrey M. Witkin
Role of Cannabinoid Receptors in Anxiety Disorders
559(14)
Aldemar Degroot
Index 573