This book covers a wide range of topics relating to carbon nanomaterials, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive chemical, physical, optical, and even magnetic properties for various applications, considerable effort has been made to employ carbon nanomaterials (e.g., fullerenes, carbon nanotubes, graphene, nanodiamond) as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Tremendous progress has been made and the scattered literature continues to grow rapidly.
With chapters by world-renowned experts providing an overview of the state of the science as well as an understanding of the challenges that lie ahead,Carbon Nanomaterials for Biomedical Applications is essential reading not only for experienced scientists and engineers in biomedical and nanomaterials areas, but also for graduate students and advanced undergraduates in materials science and engineering, chemistry, and biology.
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Part I Carbon Nanomaterials for Biomedical Applications |
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1 Perspectives on Carbon Nanomaterials in Medicine Based upon Physicochemical Properties: Nanotubes, Nanodiamonds, and Carbon Nanobombs |
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3 | (28) |
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2 Carbon Nanomaterials for Drug Delivery |
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31 | (50) |
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3 Cytotoxicity, Drug Delivery, and Photothermal Therapy of Functionalized Carbon Nanomaterials |
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81 | (32) |
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4 Carbon Nanotubes with Special Architectures for Biomedical Applications |
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113 | (32) |
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5 Photodynamic Therapy with Water-Soluble Cationic Fullerene Derivatives |
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145 | (56) |
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6 Carbon Nanotube Field-Emission X-Ray-Based Micro-computed Tomography for Biomedical Imaging |
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201 | (26) |
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7 Nanotubes/Polymethyl Methacrylate Composite Resins as Denture Base Materials |
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227 | (14) |
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8 Graphene for biomedical applications |
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241 | (28) |
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9 Bionic Graphene Nanosensors |
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269 | (30) |
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10 Functionalized Carbon Nanodots for Biomedical Applications |
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299 | (20) |
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11 Nanodiamonds: Behavior in Biological Systems and Emerging Bioapplications |
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319 | (46) |
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Part II Nanotechnology for Biomedical Applications: From Carbon Nanomaterials to Biomimetic/Bioinspired Systems |
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12 Bio-Inspired Engineering of 3D Carbon Nanostructures |
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365 | (56) |
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13 Janus Nanostructures for Biomedical Applications: Dual-Surfaces of Single Particle for Multifunctionality |
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421 | (24) |
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14 Protein Nanopatterning |
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445 | (36) |
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15 Biomimetic Approach to Designing Adhesive Hydrogels: From Chemistry to Application |
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481 | (20) |
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16 Measuring Lipid Bilayer Permeability with Biomimetic Membranes |
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501 | (32) |
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17 Fluorescent Nanosensor for Drug Discovery |
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533 | (10) |
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18 Biomimetic Surfaces for Cell Engineering |
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543 | (28) |
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Index |
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571 | |
Mei Zhang is a Research Assistant Professor in the Department of Biomedical Engineering. She also holds a joint appointment in University Hospitals-Case Comprehensive Cancer Center. Zhang's expertise ranges across the synthesis and characterization of polymers and nanomaterials, nanotechnology, tumor immunology, and immunotherapy in the treatment of cancer. Her primary research interest is to apply polymer materials to the design and development of novel nanoparticle systems for multifunctional applications, including gene drug delivery, biomedical imaging, and bio-energy systems (e.g., bio-fuel cells).
Rajesh Naik is the Research Group Leader in the Soft Matter Materials Branch of the Materials and Manufacturing Directorate at Air Force Research Laboratory. Naiks expertise is in the area of biomaterials, nanomaterials, and bionanotechnology. His interests is primarily in developing biomimetic materials and devices for aerospace applications.
Liming Dai is the Kent Hale Smith Professor in the Department of Macromolecular Science and Engineering at Case Western Reserve University (CWRU). He is also director of the Center of Advanced Science and Engineering for Carbon (CASE4Carbon). Before joining the CWRU, he was an associate professor of polymer engineering at the University of Akron and the Wright Brothers Institute Endowed Chair Professor of Nanomaterials at the University of Dayton. Dr. Dais expertise lies across the synthesis, chemical modification and device fabrication of conjugated polymers and carbon nanomaterials for energy-related and biomedical applications.