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El. knyga: Cell Structure & Function

Edited by (St John's Institute of Dermatology, St Thomas' Hospital, London), Edited by (Editor of British Journal of Biomedical Science)
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Describes the structural and functional features of the various types of cell from which the human body is formed, focusing on normal cellular structure and function and giving students and trainees a firm grounding in the appearance and behavior of healthy cells and tissues on which can be built a robust understanding of cellular pathology.

Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible.

The Fundamentals of Biomedical Science series is written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis.

Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science.
Alongside volumes exploring specific biomedical themes and related laboratory diagnosis, an overarching Biomedical Science Practice volume gives a grounding in the professional and experimental skills with which any Biomedical Scientist must be equipped.

The series:
DT Understands the complex roles of Biomedical Scientists in the modern practice of medicine
DT Understands the development needs of employers and the Profession
DT Addresses the need for understanding of a range of fundamental sciences in the context of Biomedicine
DT Places the theoretical aspects of Biomedical Science in their practical context

Cell Structure and Function describes the structural and functional features of the various types of cell from which the human body is formed. Focusing on normal cellular structure and function, it gives students and trainees a firm grounding in the appearance and behaviour of healthy cells and tissues on which can be built a robust understanding of cellular pathology.

With cell structure and function correlated with clinical contexts throughout, Cell Structure and Function is the ideal introduction to cellular biology for any student of biomedical science.

Online Resource Centre
The Online Resource Centre to accompany the Fundamentals of Biomedical Science series features:

For registered adopters of the book:
DT Figures from each book, available to download

For students:
DT An interactive Digital Microscope, encouraging the exploration of tissue samples
DT Video podcasts including interviews with practicing biomedical scientists, and 'in the lab' footage showing biomedical science in practice

Recenzijos

Well illustrated with numerous schematic drawings which are extremely helpful for the explanation and clarification of difficult concepts. * The Journal of Histotechnology, March 2015 * The text is succinct and well written. Numerous well thought-out tables help with the organization of material for the reader. * The Journal of Histotechnology, March 2015 * A great introductory textbook to the fascinating world of cellular structure and function. * The Journal of Histotechnology, March 2015 * The amount of information, the great illustrations and the well-written text make this book a great bargain for every bio-scientist. * The Journal of Histotechnology, March 2015 *

1 Introducing the cell: the unit of life
1(45)
Carole Hackney
David Furness
1.1 Development of cell theory
4(4)
1.2 Origins of cells
8(2)
1.3 Diversity of prokaryotic cells
10(1)
1.4 The general structure of eukaryotic cells
10(2)
1.5 Membrane systems
12(4)
1.6 Nucleus
16(2)
1.7 Cytoplasm
18(8)
1.8 Membrane systems and disease
26(9)
1.9 Cell division
35(6)
1.10 Different cells and tissue formation
41(5)
Chapter summary
44(1)
Further reading
44(1)
Discussion questions
45(1)
2 Studying cells: essential techniques
46(36)
Gavin Knight
2.1 Where did the study of cells begin?
46(1)
2.2 Introduction to microscopy
47(13)
2.3 Visualization of microscopic structures
60(2)
2.4 Introduction to cytometrics
62(3)
2.5 Cytogenetic analysis
65(5)
2.6 Molecular biology
70(12)
Chapter summary
80(1)
Further reading
80(1)
Discussion questions
81(1)
3 Introduction to anatomy and embryology
82(29)
Joanne Murray
Ian Locke
3.1 Fine and gross anatomy, cells, tissues, organs and systems
86(6)
3.2 Embryology and fetal development
92(12)
3.3 Growth and development
104(7)
Chapter summary
108(1)
Further reading
109(1)
Discussion questions
110(1)
4 Blood cell genesis: red cell, white cell and platelet families
111(30)
Gavin Knight
4.1 Cellular components of the blood
111(6)
4.2 Introduction to blood cell production
117(3)
4.3 Structure of the bone marrow
120(2)
4.4 Stem cells as the ultimate haemopoietic precursor
122(2)
4.5 Control of haemopoiesis
124(1)
4.6 First stages of haemopoiesis
125(4)
4.7 Erythropoiesis
129(1)
4.8 Hierarchy of erythropoiesis
130(2)
4.9 Thrombopoiesis
132(2)
4.10 Haemostasis and the role of platelets
134(1)
4.11 Granulopoiesis
135(1)
4.12 Monopoiesis
135(2)
4.13 Abnormal haemopoiesis
137(4)
Chapter summary
139(1)
Further reading
139(1)
Discussion questions
139(2)
5 Nerves: the cells of the central and peripheral nervous systems
141(46)
Rosalind King
Richard Mathias
5.1 Neurons
142(9)
5.2 Glial cells
151(5)
5.3 Cells and structures of the peripheral nervous system
156(6)
5.4 Structural organization of the nervous system
162(6)
5.5 Functional divisions of the peripheral nervous system
168(3)
5.6 Sensory reception in the peripheral nervous system
171(6)
5.7 Endocrine function and control in the central nervous system
177(3)
5.8 Tumours of the central nervous system
180(2)
5.9 Pathological processes in the peripheral nervous system
182(5)
Chapter summary
186(1)
Further reading
186(1)
Discussion questions
186(1)
6 Lungs: the cells of the respiratory system
187(33)
Behdad Shambayati
Andrew Evered
6.1 Respiratory epithelium
187(3)
6.2 Nasal cavity
190(2)
6.3 Paranasal sinuses
192(2)
6.4 Nasopharynx
194(1)
6.5 Larynx
194(2)
6.6 Trachea
196(3)
6.7 Lungs
199(1)
6.8 Bronchial tree
200(7)
6.9 Bronchioles
207(4)
6.10 Respiratory bronchioles
211(1)
6.11 Alveolar ducts
211(1)
6.12 Alveoli
211(3)
6.13 Macrophages
214(1)
6.14 Blood vessels
215(1)
6.15 Pleura
215(5)
Chapter summary
218(1)
Further reading
218(1)
Discussion questions
219(1)
7 Digestive system
220(26)
Tony Warford
Tony Madgwick
7.1 General structural arrangement
221(4)
7.2 Oral cavity
225(6)
7.3 Oesophagus
231(1)
7.4 Stomach
232(2)
7.5 Small intestine
234(6)
7.6 Large intestine
240(3)
7.7 The intestine and cancer
243(3)
Chapter summary
243(1)
Further reading
244(1)
Discussion questions
245(1)
8 Cells and microbial flora of the gastrointestinal tract
246(17)
Kathy Nye
8.1 General principles and the development of the normal microflora
247(3)
8.2 Regions of the GI tract and their normal microbial flora
250(4)
8.3 Functions of the normal flora
254(3)
8.4 Normal flora in disease states
257(2)
8.5 Therapeutic manipulation of the normal flora
259(4)
Chapter summary
261(1)
Further reading
261(1)
Discussion questions
262(1)
9 Cells of the cardiovascular and lymphatic systems
263(33)
Andrew Blann
9.1 Overview of the cardiovascular and lymphatic systems
263(1)
9.2 Cells of the cardiovascular and lymphatic systems
264(11)
9.3 Vessels of the cardiovascular and lymphatic systems
275(7)
9.4 Organs of the cardiovascular and lymphatic systems
282(8)
9.5 Pathology of the cardiovascular and lymphatic systems
290(6)
Chapter summary
294(1)
Further reading
294(1)
Discussion questions
295(1)
10 Musculoskeletal system
296(27)
Suha Deen
10.1 Skeletal muscle
297(11)
10.2 Bone and cartilage
308(12)
10.3 Cartilage
320(3)
Chapter summary
321(1)
Further reading
322(1)
Discussion questions
322(1)
11 Liver
323(26)
Anne Rayner
Alberto Quaglia
11.1 Segmental anatomy, blood supply and biliary drainage
325(4)
11.2 Microscopic structure
329(3)
11.3 Ultrastructure of the hepatocyte
332(2)
11.4 Other cells seen in the liver
334(2)
11.5 Bile ducts
336(1)
11.6 Liver development
336(1)
11.7 Liver regeneration
337(1)
11.8 Liver pathology
338(5)
11.9 Classification of liver disease
343(1)
11.10 Gallbladder
344(2)
11.11 Pancreas
346(3)
Chapter summary
347(1)
Further reading
348(1)
Discussion questions
348(1)
12 Kidney and urinary tract
349(30)
Guy Orchard
David Muskett
Brian Nation
12.1 Embryology
352(1)
12.2 Kidney function
352(2)
12.3 Kidney structure
354(2)
12.4 Microscopic structural features
356(11)
12.5 Renal interstitium
367(1)
12.6 Ureters
368(1)
12.7 Urinary bladder
369(2)
12.8 Urethra
371(1)
12.9 Urinary system disease
371(5)
12.10 Kidney transplantation
376(3)
Chapter summary
377(1)
Further reading
377(1)
Discussion questions
378(1)
13 Reproductive cells and gametogenesis
379(35)
Andrew Evered
Behdad Shambayati
13.1 The reproductive system--an overview
380(2)
13.2 Gametogenesis
382(5)
13.3 Testes and spermatogenesis
387(7)
13.4 Ovaries and oogenesis
394(3)
13.5 Cells of the male reproductive tract
397(3)
13.6 Cells of the female reproductive tract
400(8)
13.7 Cells of the external genitalia
408(6)
Chapter summary
411(1)
Further reading
412(1)
Discussion questions
412(2)
14 Cells of the endocrine system
414(37)
Judy Brincat
14.1 Hormone action and control mechanisms
415(2)
14.2 Pituitary gland
417(8)
14.3 Pineal gland
425(3)
14.4 Thyroid gland
428(4)
14.5 Parathyroid glands
432(2)
14.6 Adrenal glands
434(7)
14.7 Endocrine pancreas
441(3)
14.8 Gastrointestinal endocrine system
444(2)
14.9 Respiratory endocrine system
446(1)
14.10 Endocrine cells of the kidney
447(4)
Chapter summary
448(1)
Further reading
449(1)
Discussion questions
449(1)
Acknowledgements
450(1)
15 Skin and breast
451(36)
Guy Orchard
15.1 Structure of the skin
453(1)
15.2 Embryology of the skin
454(1)
15.3 Structure of the epidermis
455(4)
15.4 Cells of the epidermis
459(5)
15.5 Basement membrane zone
464(2)
15.6 Structures of the dermis
466(11)
15.7 Subcutis (subcutaneous fat)
477(1)
15.8 Breast tissue
478(4)
15.9 Stains, antibodies and descriptive terms used in dermatopathology: a brief overview
482(5)
Chapter summary
484(1)
Further reading
485(1)
Discussion questions
486(1)
Glossary 487(8)
Index 495
Dr Guy Orchard is Consultant Grade Biomedical Scientist, Laboratory Manager at Viapath, St John's Institute of Dermatology, and Viapath Operational Lead for Head and Neck Pathology at Guys Hospital, London.

Dr Brian Nation is Editor of The Biomedical Scientist, a publication of the Institute of Biomedical Science.