Phase I trials are a critical first step in the study of novel cancer therapeutic approaches. Their primary goals are to identify the recommended dose, schedule and pharmacologic behavior of new agents or new combinations of agents and to describe th...Daugiau...
Phase I trials are a critical first step in the study of novel cancer therapeutic approaches. Their primary goals are to identify the recommended dose, schedule and pharmacologic behavior of new agents or new combinations of agents and to describe th...Daugiau...
Sarah R. Brown, Walter M. Gregory, Christopher J. Twelves, Julia M. Brown
Serija: Statistics in Practice
(Išleidimo metai: 28-Mar-2014, EPUB+DRM, Leidėjas: John Wiley & Sons Inc, ISBN-13: 9781118763636)
How to identify optimal phase II trial designs Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific po...Daugiau...
Sarah R. Brown, Walter M. Gregory, Christopher J. Twelves, Julia M. Brown
Serija: Statistics in Practice
(Išleidimo metai: 11-Mar-2014, PDF+DRM, Leidėjas: John Wiley & Sons Inc, ISBN-13: 9781118763629)
How to identify optimal phase II trial designs Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific po...Daugiau...
(Išleidimo metai: 29-Mar-2011, EPUB+DRM, Leidėjas: Taylor & Francis Ltd, ISBN-13: 9781040068427)
This book presents the continual reassessment method (CRM) as a tool for dose-finding studies. With a focus on the implementation and practice of the CRM and its variations, it explains how the CRM may be calibrated and extended to suit common clinic...Daugiau...
(Išleidimo metai: 29-Mar-2011, PDF+DRM, Leidėjas: Taylor & Francis Ltd, ISBN-13: 9781420091526)
This book presents the continual reassessment method (CRM) as a tool for dose-finding studies. With a focus on the implementation and practice of the CRM and its variations, it explains how the CRM may be calibrated and extended to suit common clinic...Daugiau...
(Išleidimo metai: 25-Feb-2011, EPUB+DRM, Leidėjas: John Wiley & Sons Inc, ISBN-13: 9781118035207)
The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials guides drug development organizations in preparing a...Daugiau...
(Išleidimo metai: 03-Aug-2010, PDF+DRM, Leidėjas: John Wiley & Sons Inc, ISBN-13: 9780470613177)
The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials guides drug development organizations in preparing a...Daugiau...
(Išleidimo metai: 19-Jan-2010, PDF+DRM, Leidėjas: John Wiley & Sons Inc, ISBN-13: 9780470319178)
All new medicines and devices undergo early phase trials to assess, interpret and better understand their efficacy, tolerability and safety. An Introduction to Statistics in Early Phase Trials describes the practical design and analysis of these impo...Daugiau...
