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v | |
Foreword |
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ix | |
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Preface |
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xi | |
Color Plates |
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xiii | |
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Section I Basic concepts of atherothrombosis |
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1 | (186) |
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Fundamentals of the thrombosis cascade: interaction between platelets and the coagulation cascade |
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3 | (8) |
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Platelet receptors and their role in atherothrombosis |
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11 | (8) |
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Laboratory assessment of platelet function and coagulation |
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19 | (16) |
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Section II Antithrombotic drugs |
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33 | (2) |
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Cyclooxygenase inhibition in atherothrombotic disease |
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35 | (10) |
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P2Y12 receptor antagonism: from bench to bedside |
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45 | (8) |
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Timing, dosing and length of clopidogrel therapy |
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53 | (8) |
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Resistance to antiplatelet drugs: aspirin |
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61 | (6) |
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Resistance to antiplatelet drugs: clopidogrel |
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67 | (12) |
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Prasugrel -- a third-generation thienopyridine |
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79 | (6) |
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Direct oral P2Y12 inhibition: AZD6140 (Ticagrelor) |
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85 | (6) |
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Emerging oral antiplatelet receptor inhibitors |
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91 | (10) |
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Intravenous antiplatelet drugs |
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99 | (2) |
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Platelet glycoprotein IIb/IIIa receptor antagonists: fundamental and pharmacological aspects |
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101 | (6) |
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Platelet glycoprotein IIb/IIIa receptor antagonists: a guide to patient selection and optimal use |
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107 | (8) |
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115 | (12) |
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Thrombin inhibitors and thrombin generation inhibitors |
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125 | (2) |
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Indirect thrombin inhibitors: fundamentals and guide to optimal therapy using unfractionated heparin and low-molecular-weight heparins |
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127 | (8) |
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Direct thrombin inhibitors |
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135 | (10) |
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Fondaparinux in acute coronary syndromes |
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145 | (8) |
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153 | (10) |
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161 | (2) |
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Fibrinolytics: current indications and treatment modalities in the absence of mechanical reperfusion |
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163 | (14) |
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Fibrinolytics and percutaneous coronary intervention |
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177 | (10) |
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Francisco Fernandez-Aviles |
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Section III Special situations |
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187 | (76) |
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Role of facilitated percutaneous coronary intervention in ST-elevation myocardial infarction |
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189 | (8) |
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Antithrombotic treatment in vein graft interventions |
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197 | (8) |
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Antiplatelet therapy in diabetes mellitus |
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205 | (6) |
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Stent thrombosis in the era of drug-eluting stents |
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211 | (10) |
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Bleeding complications: anticoagulant and antiplatelet therapy control |
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221 | (8) |
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Heparin-induced thrombocytopenia: etiopathogenesis, clinical presentation, and management |
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229 | (12) |
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Antithrombotic therapies for patients with cerebrovascular, peripheral arterial, and coronary artery disease |
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241 | (10) |
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Dual antiplatelet strategies in patients requiring vitamin K antagonists |
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251 | (12) |
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Appendix |
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263 | (8) |
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Index |
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271 | |