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xi | |
Preface to the first edition |
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xxiii | |
Preface to the fourth edition |
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xxv | |
Dedication |
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xxvii | |
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PART ONE Principles of immune response |
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1 The human immune response |
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3 | (13) |
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2 Organization of the immune system |
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16 | (19) |
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35 | (12) |
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4 Antigen receptor genes, gene products, and co-receptors |
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47 | (21) |
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5 The major histocompatibility complex |
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68 | (9) |
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6 Antigens and antigen presentation |
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77 | (13) |
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7 B-cell development and differentiation |
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90 | (12) |
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102 | (6) |
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9 Cytokines and cytokine receptors |
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108 | (28) |
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10 Chemokines and chemokine receptors |
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136 | (13) |
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11 Lymphocyte adhesion and trafficking |
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149 | (11) |
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12 T-cell activation and tolerance |
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160 | (12) |
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13 Programmed cell death in lymphocytes and associated disorders |
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172 | (11) |
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PART TWO Host defense mechanisms and inflammation |
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14 Immunoglobulin function |
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183 | (10) |
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193 | (10) |
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16 Helper T-cell subsets and control of the inflammatory response |
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203 | (12) |
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17 Cytotoxic T lymphocytes and natural killer cells |
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215 | (13) |
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18 Host defenses in the skin |
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228 | (11) |
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19 Host defenses at mucosal surfaces |
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239 | (13) |
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20 Complement in host deficiencies and diseases |
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252 | (18) |
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21 Phagocyte deficiencies |
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270 | (14) |
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22 Mast cells, basophils, and mastocytosis |
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284 | (14) |
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23 Eosinophils and eosinophilia |
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298 | (15) |
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PART THREE Host defenses to infectious agents |
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24 Host defenses to extracellular bacteria |
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313 | (11) |
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25 Host defenses to intracellular bacteria |
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324 | (14) |
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26 Host defenses to spirochetes |
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338 | (8) |
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27 Host defenses to viruses |
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346 | (10) |
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28 Host defenses to protozoa |
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356 | (11) |
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29 Host defenses to helminths |
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367 | (14) |
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PART FOUR Immunologic deficiencies |
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30 Approach to the evaluation of the immunodeficient patient |
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381 | (10) |
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31 Infections in the immunocompromised host |
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391 | (14) |
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Jennifer Cuellar-Rodriguez |
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32 Maturing of the fetal and neonatal immune system |
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405 | (9) |
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33 Aging and the immune system |
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414 | (7) |
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34 Primary antibody deficiencies |
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421 | (16) |
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35 Primary T-cell immunodeficiencies |
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437 | (17) |
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36 Inherited disorders of IFN-γ-, IFN-α/β/λ-, and NF-KB-mediated immunity |
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454 | (11) |
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37 HIV infection and acquired immunodeficiency syndrome |
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465 | (15) |
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38 External factors inducing immune deficiency |
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480 | (11) |
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PART FIVE Allergic diseases |
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39 Immunological mechanisms of airway diseases and pathways to therapy |
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491 | (15) |
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40 Urticaria, angioedema, and anaphylaxis |
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506 | (16) |
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41 Allergic reactions to stinging and biting insects |
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522 | (9) |
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42 Atopic and contact dermatitis |
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531 | (12) |
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543 | (7) |
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44 Eosinophil-associated gastrointestinal disorders |
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550 | (8) |
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45 Allergic disorders of the eye |
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558 | (6) |
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564 | (14) |
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578 | (9) |
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PART SIX Systemic immune diseases |
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48 Mechanisms of autoimmunity |
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587 | (8) |
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49 Interface of autoimmunity and immunodeficiency |
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595 | (8) |
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50 Systemic lupus erythematosus |
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603 | (18) |
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621 | (16) |
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52 Juvenile idiopathic arthritis |
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637 | (11) |
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648 | (8) |
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54 Scleroderma-systemic sclerosis |
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656 | (11) |
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55 Inflammatory muscle diseases |
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667 | (9) |
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676 | (17) |
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57 Small and medium vessel primary vasculitis |
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693 | (23) |
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58 Large-vessel vasculitides |
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716 | (12) |
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59 Systemic autoinflammatory syndromes |
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728 | (12) |
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Jeroen C.H. van der Hilst |
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60 Antiphospholipid syndrome |
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740 | (9) |
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PART SEVEN Organ-specific inflammatory disease |
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61 Immunohematologic disorders |
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749 | (11) |
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62 Bullous diseases of the skin and mucous membranes |
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760 | (15) |
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63 Immunology of psoriasis |
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775 | (7) |
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782 | (11) |
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793 | (8) |
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66 Autoimmune peripheral neuropathies |
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801 | (11) |
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67 Immunologic renal diseases |
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812 | (16) |
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68 Inflammation and atherothrombosis |
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828 | (9) |
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69 Autoimmune thyroid diseases |
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837 | (10) |
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70 Diabetes and related autoimmune diseases |
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847 | (13) |
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71 Immunologic lung diseases |
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860 | (14) |
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874 | (11) |
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73 Immunologic ocular disease |
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885 | (11) |
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74 Immunologic diseases of the gastrointestinal tract |
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896 | (14) |
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75 Inflammatory hepatobiliary diseases |
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910 | (15) |
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PART EIGHT Immunology of neoplasia |
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76 Principles of tumor immunology |
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925 | (10) |
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935 | (11) |
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946 | (16) |
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962 | (13) |
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80 Monoclonal gammopathies |
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975 | (14) |
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PART NINE Transplantation |
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81 Concepts and challenges in organ transplantation: rejection, immunosuppression, and tolerance |
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989 | (18) |
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82 Stem cell transplantation and immune reconstitution in immunodeficiency |
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1007 | (13) |
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83 Hematopoietic stem cell transplantation for malignant diseases |
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1020 | (12) |
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1032 | (9) |
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PART TEN Prevention and therapy of immunologic diseases |
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85 Immunoglobulin therapy: replacement and immunomodulation |
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1041 | (13) |
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1054 | (12) |
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1066 | (11) |
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88 Immunomodulating pharmaceuticals |
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1077 | (8) |
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89 Protein kinase antagonists as therapeutic agents for immunological and inflammatory disorders |
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1085 | (10) |
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1095 | (27) |
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91 Immunotherapy of allergic disease |
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1122 | (9) |
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92 Biologic modifiers of inflammatory diseases |
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1131 | (14) |
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PART ELEVEN Diagnostic immunology |
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93 Assessment of proteins of the immune system |
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1145 | (15) |
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1160 | (12) |
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95 Assessment of functional immune responses |
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1172 | (11) |
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96 Assessment of neutrophil function |
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1183 | (9) |
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97 Assessment of human allergic diseases |
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1192 | (10) |
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1202 | (13) |
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A1 Selected CD molecules and their characteristics |
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1215 | (6) |
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A2 Laboratory reference values |
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1221 | (3) |
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1224 | (3) |
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1227 | (5) |
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1232 | (3) |
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Index |
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1235 | |