Preface to the First Edition |
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Preface to the Fifth Edition |
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Dedication |
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xviii | |
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PART ONE Principles of Immune Response |
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1 The Human Immune Response |
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3 | (16) |
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2 Organization of the Immune System |
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19 | (20) |
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39 | (16) |
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4 Antigen Receptor Genes, Gene Products, and Coreceptors |
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55 | (24) |
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5 The Major Histocompatibility Complex |
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79 | (14) |
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6 Overview of T-Cell Recognition: Making Pathogens Visible to the Immune System |
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93 | (14) |
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7 B-Cell Development and Differentiation |
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107 | (12) |
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119 | (8) |
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9 Cytokines and Cytokine Receptors |
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127 | (30) |
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10 Chemokines and Chemokine Receptors |
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157 | (14) |
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11 Lymphocyte Adhesion and Trafficking |
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171 | (12) |
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12 T-Cell Activation and Tolerance |
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183 | (14) |
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13 Regulated Necrosis and Its Immunogenicity |
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197 | (10) |
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14 The Microbiota in Immunity and Inflammation |
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207 | (16) |
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PART TWO Host Defense Mechanisms and Inflammation |
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15 Immunoglobulin Function |
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223 | (12) |
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16 Helper T-Cell Subsets and Control of the Inflammatory Response |
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235 | (12) |
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17 Cytotoxic T Lymphocytes and Natural Killer Cells |
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247 | (14) |
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18 Regulatory Immune Cells |
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261 | (12) |
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273 | (12) |
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20 Host Defenses at Mucosal Surfaces |
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285 | (14) |
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21 The Human Complement System: Basic Concepts and Clinical Relevance |
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299 | (20) |
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22 Phagocyte Deficiencies |
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319 | (16) |
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23 Mast Cells, Basophils, and Mastocytosis |
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335 | (14) |
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24 Eosinophils and Eosinophilia |
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349 | (16) |
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PART THREE Host Defenses to Infectious Agents |
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25 Host Defenses to Viruses |
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365 | (10) |
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26 Host Defenses to Intracellular Bacteria |
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375 | (16) |
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27 Host Defenses to Extracellular Bacteria |
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391 | (12) |
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28 Host Defenses to Spirochetes |
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403 | (10) |
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29 Host Defenses to Fungal Pathogens |
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413 | (12) |
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30 Host Defenses to Protozoa |
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425 | (12) |
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31 Immune Responses to Helminth Infection |
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437 | (14) |
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PART FOUR Immunological Deficiencies |
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32 Approach to the Evaluation of the Patient With Suspected Immunodeficiency |
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451 | (12) |
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33 Human Genomics in Immunology |
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463 | (8) |
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34 Primary Antibody Deficiencies |
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471 | (18) |
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35 Primary T-Cell Immunodeficiencies |
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489 | (20) |
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36 Immunodeficiencies at the Interface of Innate and Adaptive Immunity |
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509 | (14) |
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37 Infections in the Immunocompromised Host |
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523 | (12) |
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Jennifer M. Cuellar-Rodriguez |
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38 Immune Deficiencies at the Extremes of Age |
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535 | (10) |
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39 Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome |
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545 | (16) |
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40 Autoantibody-Mediated Phenocopies of Primary Immunodeficiency Diseases |
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561 | (10) |
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PART FIVE Allergic Diseases |
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41 Immunological Mechanisms of Airway Diseases and Pathways to Therapy |
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571 | (14) |
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42 Urticaria, Angioedema, and Anaphylaxis |
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585 | (16) |
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43 Allergic Reactions to Stinging and Biting Insects |
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601 | (10) |
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44 Atopic and Contact Dermatitis |
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611 | (14) |
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625 | (8) |
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46 Eosinophil-Associated Gastrointestinal Disorders |
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633 | (8) |
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47 Allergic Disorders of the Eye |
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641 | (8) |
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649 | (20) |
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49 Occupational Respiratory Allergies |
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669 | (8) |
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PART SIX Systemic Immune Diseases |
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50 Mechanisms of Autoimmunity |
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677 | (8) |
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51 Systemic Lupus Erythematosus |
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685 | (20) |
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705 | (18) |
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53 Juvenile Idiopathic Arthritis |
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723 | (12) |
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735 | (8) |
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55 Scleroderma---Systemic Sclerosis |
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743 | (14) |
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56 Inflammatory Muscle Diseases |
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757 | (12) |
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769 | (20) |
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58 Small- and Medium-Vessel Primary Vasculitis |
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789 | (20) |
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59 Large-Vessel Vasculitides |
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809 | (16) |
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60 Systemic Autoinflammatory Syndromes |
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825 | (10) |
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Catharina M. Mulders-Manders |
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Jeroen C.H. van der Hilst |
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61 Antiphospholipid Syndrome |
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835 | (10) |
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PART SEVEN Organ-Specific Inflammatory Disease |
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62 Immunohematological Disorders |
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845 | (12) |
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63 Bullous Diseases of the Skin and Mucous Membranes |
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857 | (14) |
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64 Immunology of Psoriasis |
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871 | (8) |
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879 | (12) |
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891 | (12) |
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67 Autoimmune Peripheral Neuropathies |
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903 | (14) |
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68 Immunological Renal Diseases |
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917 | (18) |
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69 Inflammation and Atherothrombosis |
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935 | (12) |
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70 Autoimmune Thyroid Diseases |
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947 | (10) |
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957 | (10) |
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72 Immunological Lung Diseases |
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967 | (14) |
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981 | (12) |
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74 Immunological Ocular Disease |
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993 | (12) |
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75 Immunological Diseases of the Gastrointestinal Tract |
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1005 | (16) |
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76 Inflammatory Hepatobiliary Diseases |
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1021 | (12) |
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PART EIGHT Immunology of Neoplasia |
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77 Immunotherapy of Cancer |
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1033 | (16) |
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1049 | (16) |
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1065 | (14) |
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80 Monoclonal Gammopathies |
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1079 | (18) |
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PART NINE Transplantation |
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81 Concepts and Challenges in Organ Transplantation: Rejection, Immunosuppression, and Tolerance |
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1097 | (18) |
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82 Immune Reconstitution Therapy for Immunodeficiency |
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1115 | (14) |
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83 Hematopoietic Stem Cell Transplantation for Malignant Diseases |
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1129 | (14) |
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PART TEN Prevention and Therapy of Immunological Diseases |
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84 Immunoglobulin Therapy: Replacement and Immunomodulation |
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1143 | (12) |
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85 Gene Therapy for Primary Immune Deficiency Diseases |
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1155 | (10) |
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1165 | (12) |
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87 Immunomodulating Pharmaceuticals |
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1177 | (8) |
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88 Protein Kinase Antagonists in Therapy of Immunological and Inflammatory Diseases |
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1185 | (12) |
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89 Biological Modifiers of Inflammatory Diseases |
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1197 | (14) |
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1211 | (16) |
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91 Immunotherapy of Allergic Disease |
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1227 | (12) |
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PART ELEVEN Diagnostic Immunology |
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1239 | (14) |
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93 Assessment of Functional Immune Responses in Lymphocytes |
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1253 | (20) |
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94 Assessment of Neutrophil Function |
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1273 | (10) |
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95 Assessment of Human Allergic Diseases |
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1283 | (14) |
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1297 | (14) |
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A1 Selected CD Molecules and Their Characteristics |
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1311 | (6) |
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A2 Laboratory Reference Values |
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1317 | (2) |
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Index |
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