INTRODUCTION | |
Population Heterogeneity: the Natural Genesis of Mixture Models | |
Some Examples | |
Classification Using Posterior Bayes | |
Parametric or Nonparametric Mixture Models | |
Connection to Empirical Bayes Estimation | |
THEORY OF NONPARAMETRIC MIXTURE MODELS | |
The Likelihood and its Properties | |
The Directional Derivative and the Gradient Function | |
The General Mixture Maximum Likelihood Theorem | |
Applications of the Theorem | |
ALGORITHMS | |
Vertex Direction Method | |
Vertex Exchange Method | |
Step-Length Choices | |
C.A. MAN | |
The EM Algorithm for the Fixed Component Case | |
THE LIKELIHOOD RATIO TEST FOR THE NUMBER OF COMPONENTS | |
The Problem | |
Some Analytical Solutions | |
Simulation and Bootstrap Solutions | |
C.A.MAN-APPLICATION: META-ANALYSIS | |
Conventional Approach | |
Heterogeneity | |
C.A.MAN Solution for Modeling Heterogeneity | |
Classification of Studies Using Posterior Bayes | |
MOMENT ESTIMATORS OF THE VARIANCE OF MIXING DISTRIBUTION | |
The DerSimonian-Laird Estimator | |
The Bohning-Sarol Estimator | |
Estimation of Binomia- or Poisson Rate Under Heterogeneity | |
C.A. MAN-APPLICATION: DISEASE MAPPING | |
Conventional Approach I: Mapping Percentiles | |
Conventional Approach II: Mapping P-Values | |
Estimating Map Heterogeneity | |
OTHER C.A. MAN APPLICATIONS | |
Fertility Studies | |
Modeling the Diagnostic Situation | |
Interval-Censored Survival Data |