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El. knyga: Computer Scientist's Guide to Cell Biology

3.70/5 (85 ratings by Goodreads)
  • Formatas: PDF+DRM
  • Išleidimo metai: 23-Jul-2007
  • Leidėjas: Springer-Verlag New York Inc.
  • Kalba: eng
  • ISBN-13: 9780387482781
Kitos knygos pagal šią temą:
  • Formatas: PDF+DRM
  • Išleidimo metai: 23-Jul-2007
  • Leidėjas: Springer-Verlag New York Inc.
  • Kalba: eng
  • ISBN-13: 9780387482781
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A Computer Scientists Guide to Cell Biology provides a "reading knowledge" of biology to those coming into the field from the perspective of computer science-particularly from the areas of information retrieval and/or machine learning.



The text explores three different facets of biology: biological systems, experimental methods, and language and nomenclature. The author discusses what biologists are trying to determine from their experiments, how various experimental procedures are used and how they relate to accepted concepts in computer science, and the vocabulary necessary to read and understand current literature in biology.



Researchers, professionals and computer science students will find this an invaluable reference tool and an excellent starting point for a more comprehensive examination of cell biology.

Recenzijos

From the reviews:



"This concise book is an excellent introduction for computer scientists to the exciting revolution under way in molecular biology. It provides lucid, high-level descriptions of the fundamental molecular mechanisms of life, and discusses the computational principles involved. I wish this little gem was available when I was 'learning the ropes' -- it would have been my first choice of reading material."









--Roni Rosenfeld, Carnegie Mellon University



"Cell biology is certainly a new and exciting area. This nice, compact, and enthusiastically written book covers a huge amount of material. The author describes biological systems, experimental methods, and the language of cell biology. Summing up, this book (with its excellent index) can be used as one of the first steps in obtaining a reading knowledge of biology -- though cautiously." (H. I. Kilov, Computing Reviews, December, 2007)

List of Figures
xi
Introduction xiii
How Cells Work
1(18)
Prokaryotes: the simplest living things
1(3)
Even simpler ``living'' things: viruses and plasmids
4(2)
All complex living things are eukaryotes
6(3)
Cells cooperate
9(5)
Cells divide and multiply
14(5)
The Complexity of Living Things
19(18)
Complexes and pathways
19(2)
Individual interactions can be complicated
21(8)
Energy and pathways
29(2)
Amplification and pathways
31(2)
Modularity and locality in biology
33(4)
Looking at Very Small Things
37(8)
Limitations of optical microscopes
37(2)
Special types of microscopes
39(3)
Electron microscopes
42(3)
Manipulation of the Very Small
45(14)
Taking small things apart
45(8)
Parallelism, automation, and re-use in biology
53(2)
Classifying small things taking them apart
55(4)
Reprogramming Cells
59(12)
Our colleagues, the microorganisms
59(1)
Restriction enzymes and restriction-methylase systems
59(1)
Constructing recombinant DNA with REs and DNA ligase
60(2)
Inserting foreign DNA into a cell
62(2)
Genomic DNA libraries
64(1)
Creating novel proteins: tagging and phage display
65(2)
Yeast two-hybrid assays using fusion proteins
67(4)
Other Ways to Use Biology for Biological Experiments
71(12)
Replicating DNA in a test tube
71(4)
Sequencing DNA partial replication and sorting
75(1)
Other in vitro systems: translation and reverse transcription
76(1)
Exploiting the natural defenses of a cell: Antibodies
77(1)
Exploiting the natural defenses of a cell: RNA interference
78(1)
Serial analysis of gene expression
79(4)
Bioinformatics
83(8)
Where to go from here?
91(3)
Acknowledgements 94(1)
Index 95