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El. knyga: CURRENT Diagnosis & Treatment Gastroenterology, Hepatology, & Endoscopy, Third Edition

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  • Formatas: 624 pages
  • Išleidimo metai: 22-Oct-2015
  • Leidėjas: McGraw-Hill Professional
  • Kalba: eng
  • ISBN-13: 9780071837736
Kitos knygos pagal šią temą:
  • Formatas: 624 pages
  • Išleidimo metai: 22-Oct-2015
  • Leidėjas: McGraw-Hill Professional
  • Kalba: eng
  • ISBN-13: 9780071837736
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The ultimate clinical companion for managing digestive and liver diseases—now revised and updated!

Part of the acclaimed CURRENT series, this trusted, practical resource reviews how to diagnose and treat the entire spectrum of digestive tract and liver disorders.

Authored by faculty physicians at Harvard Medical School and Brigham and Women's Hospital, CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy features a streamlined, consistent presentation, with each chapter outlining the essentials of diagnosis for each condition.

The third edition of this skill-building guide incorporates the latest research and takes you through therapeutic advances in Barrett’s esophagus, eosinophilic esophagitis, esophageal motility disorders, inflammatory bowel disease, and other conditions. Altogether, CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy is more current—and more indispensable—than ever. Page after page, it puts the most important insights on managing digestive and hepatic diseases in the palm of your hand.

  • Authoritative coverage of the entire spectrum of gastroenterology and hepatology conditions, from stomach and esophageal to pancreatic and liver disorders
  • "Essentials of Diagnosis” bulleted lists provide an at-a-glance review of both common and rare digestive disorders 
  • More than 90 full-color endoscopic and radiographic images enhance clinical decision-making and clarify imaging techniques
  • Logical organization begins with a section on general concerns such as acute abdominal pain, then progresses to specific disease categories
  • NEW! Chapter on gastrointestinal manifestations of mast cell disorders provides an important update on this increasingly recognized disorder
  • NEW! Timely coverage of the revised Atlanta Guidelines for acute pancreatitis gets you up to speed on diagnostic and treatment approaches for this common condition
  • NEW! High-yield overview of an effective treatment approach for chronic hepatitis C provides key perspectives on improving patient outcomes 
  • NEW! Updated references now include clinically relevant articles published in 2014 

 

 

Authors ix
Preface xiii
Section I. General Concerns
1 Acute Abdominal Pain: Basic Principles & Current Challenges
1(13)
Frederick L. Makrauer
Norton J. Greenberger
Acute Abdominal Pain in the Elderly
4(1)
Nonsurgical Disorders Simulating the Acute Abdomen
4(1)
Evaluation of the Acute Abdomen
5(4)
Acute Appendicitis
9(3)
Unique Presentations of Appendicitis
12(2)
2 Inflammatory Bowel Disease: Immunologic Considerations & Therapeutic Implications
14(12)
Richard S. Blumberg
Scott B. Snapper
General Principles of the Gut-Associated Lymphoid Tissues
16(2)
Pathogenesis of Inflammatory Bowel Disease
18(3)
Pathogenesis of Crohn Disease: Underlying Mechanisms of Immune Dysregulation
21(1)
Pathogenesis of Ulcerative Colitis: Immunologic Factors
21(1)
Regulatory Pathways in the Maintenance of Intestinal Tolerance
22(2)
Therapeutic Implications of the Immunobiology of Inflammatory Bowel Disease
24(2)
3 Inflammatory Bowel Disease: Medical Considerations
26(14)
Jonathan S. Levine
Robert Burakoff
General Considerations
26(1)
Clinical Findings
27(3)
Differential Diagnosis
30(2)
Complications
32(1)
Vaccinations
33(1)
Treatment
34(5)
Prognosis
39(1)
4 Inflammatory Bowel Disease: Surgical Considerations
40(11)
Jennifer L. Irani
Ronald Bleday
Ulcerative Colitis
40(4)
Crohn Disease
44(7)
5 Acute Diarrhea! Disorders
51(22)
Jerry S. Trier
Acute Diarrhea
51(5)
Acute Diarrheal Disease Caused by Specific Infections
56(17)
6 Mesenteric Vascular Disease
73(11)
Elena M. Stoffel
Kunal Jajoo
Norton J. Greenberger
Mesenteric Ischemia
73(1)
Acute Mesenteric Ischemia
74(6)
Chronic Mesenteric Ischemia
80(1)
Colonic Ischemia
81(3)
7 Gastrointestinal & Biliary Complications of Pregnancy
84(28)
Sonia Friedman
Jaya R. Agrawal
Gastroesophageal Reflux Disease
84(3)
Nausea & Vomiting
87(3)
Hyperemesis Gravidarum
90(1)
Constipation
91(1)
Diarrhea
91(1)
Hemorrhoids
92(1)
Irritable Bowel Syndrome
93(2)
Fecal Incontinence
95(1)
Inflammatory Bowel Disease
95(7)
Abdominal Pain
102(1)
Peptic Ulcer Disease
103(1)
Biliary Disease
103(1)
Pancreatitis
104(1)
Appendicitis
105(1)
Intestinal Obstruction, Pseudo-Obstruction, & Gastrointestinal Cancer
106(1)
Endoscopy in Pregnancy
106(6)
8 Hepatic Complications of Pregnancy
112(7)
Nikroo Hashemi
Chinweike Ukomado
Interpretation of Liver Biochemical Tests During Pregnancy
112(1)
Hepatic Conditions Unique to Pregnancy
113(3)
Conditions not Unique to Pregnancy
116(3)
9 State-of-the-Art Imaging of the Gastrointestinal System
119(31)
Francesco Alessandrino
Koenraad J. Mortele
Gastrointestinal Tract Imaging
119(15)
Liver Imaging
134(5)
Biliary Imaging
139(5)
Pancreatic Imaging
144(5)
Summary of Current Recommendations
149(1)
10 Gastrointestinal Manifestations of Immunodeficiency
150(7)
Zhenglun Zhu
General Considerations
150(1)
Pathogenesis
150(2)
Clinical Findings
152(1)
Treatment
153(4)
Section II. Esophageal Diseases
11 Gastroesophageal Reflux Disease
157(10)
Walter W. Chan
John R. Saltzman
General Considerations
157(1)
Clinical Findings
158(4)
Complications
162(1)
Treatment
162(4)
Course & Prognosis
166(1)
12 Barrett Esophagus
167(7)
Kunal Jajoo
John R. Saltzman
General Considerations
167(1)
Clinical Findings
168(3)
Treatment
171(2)
Course & Prognosis
173(1)
13 Oropharyngeal & Esophageal Motility Disorders
174(19)
Hiroshi Mashimo
Oropharyngeal Dysphagia
174(4)
Impaired Ues Relaxation, Cricopharyngeal Spasms, & Cricopharyngeal Bar
178(1)
Zenker Diverticulum
179(1)
Globus Pharyngeus
179(1)
Esophageal Motility Disorders
179(1)
Esophageal Motor Dysphagia
180(2)
Gastroesophageal Reflux Disease
182(1)
Esophageal Chest Pain
183(3)
Disorders of Inhibitory Innervation
186(4)
Disorders of Excitatory Nerves And Smooth Muscles
190(3)
14 Eosinophilic Esophagitis
193(4)
Norton J. Greenberger
General Considerations
193(1)
Epidemiology
193(1)
Pathogenesis
193(1)
Clinical Findings
194(1)
Differential Diagnosis
194(1)
Treatment
195(1)
Course & Prognosis
196(1)
Unresolved Issues
196(1)
Section III. Diseases of the Stomach
15 Peptic Ulcer Disease
197(12)
Edward Lew
General Considerations
197(1)
Pathogenesis
198(1)
Clinical Findings
199(3)
Differential Diagnosis
202(1)
Complications
202(1)
Treatment
202(7)
16 Zollinger-Ellison Syndrome (Gastrinoma)
209(6)
Edward Lew
General Considerations
209(1)
Pathogenesis
209(1)
Classification
209(1)
Clinical Findings
210(3)
Treatment
213(1)
Prognosis
214(1)
17 Functional (Nonulcer) Dyspepsia
215(12)
Walter W. Chan
Robert Burakoff
General Considerations
215(1)
Pathogenesis
216(3)
Clinical Findings
219(2)
Differential Diagnosis
221(1)
Treatment
222(4)
Course & Prognosis
226(1)
18 Disorders of Gastric & Small Bowel Motility
227(11)
Walter W. Chan
Robert Burakoff
Gastroparesis & Chronic Intestinal Pseudo-Obstruction
228(9)
Dumping Syndrome & Accelerated Gastric Emptying
237(1)
Rapid Transit Dysmotility of the Small Bowel
237(1)
19 Treatment of Obesity: The Impact of Bariatric Surgery
238(13)
Malcolm K. Robinson
Norton J. Greenberger
Treatment of Overweight & Obese Patients
239(1)
Indications for Bariatric Surgery
240(1)
Bariatric Surgical Procedures
241(3)
Postoperative Care & Complications
244(2)
Gastroenterology Evaluation & Treatment
246(2)
Long-Term Outcome of Bariatric Surgery
248(2)
Recommendations & Caveats
250(1)
Section IV. Small Bowel Diseases
20 Intestinal Malabsorption
251(23)
Jerry S. Trier
Diseases Associated With Intraluminal Maldigestion
257(3)
Diseases Associated with Impaired Mucosal Digestion & Absorption
260(10)
Diseases Caused by Impairment of Both Intraluminal Digestion & Mucosal Digestion/Absorption
270(2)
Diseases Caused by Impaired Postmucosal Transport
272(2)
Section V. Colorectal Diseases
21 Diverticular Disease of the Colon
274(14)
Anne C. Travis
Diverticulosis
274(5)
Acute Diverticulitis
279(5)
Diverticular Hemorrhage
284(4)
22 Colorectal Cancer Screening
288(16)
Ramona Lim
Sapna Syngal
Fay Kastrinos
Risk Stratification
289(1)
Screening & Surveillance Recommendations
290(6)
Screening Modalities
296(4)
Additional Screening Modalities
300(3)
Summary of Recommendations
303(1)
23 Hereditary Gastrointestinal Cancer Syndromes
304(12)
Ramona Lim
Sapna Syngal
Elena M. Stoffel
Hereditary Colorectal Cancer Syndromes
304(7)
Hamartomatous Polyposis Syndromes
311(1)
Serrated Polyposis Syndrome
312(1)
Colorectal Polyposis Not Otherwise Specified
313(1)
Other Gastrointestinal Cancer Syndromes
313(3)
24 Irritable Bowel Syndrome
316(12)
Sonia Friedman
General Considerations
316(1)
Pathogenesis
317(2)
Clinical Findings
319(2)
Differential Diagnosis
321(4)
Complications
325(1)
Treatment
325(3)
25 Mast Cell Disorders
328(7)
Matthew J. Hamilton
Mariana Castells
Norton J. Greenberger
General Considerations
328(1)
Classifications of Mast Cell Disorders
329(1)
Pathogenesis of Mast Cell Disorders
330(1)
Clinical Findings
330(2)
Differential Diagnosis
332(1)
Treatment
332(2)
Clinical Course and Prognosis
334(1)
Unresolved Issues
334(1)
Section VI. Pancreatic Diseases
26 Acute Pancreatitis
335(8)
Darwin L. Conwell
Peter A. Banks
General Considerations
335(1)
Pathogenesis
336(1)
Clinical Findings
337(3)
Differential Diagnosis
340(1)
Complications
340(1)
Treatment
341(2)
27 Chronic Pancreatitis
343(9)
Darwin L. Conwell
Peter A. Banks
General Considerations
343(1)
Pathogenesis
343(2)
Clinical Findings
345(4)
Differential Diagnosis
349(1)
Complications
349(1)
Treatment
349(2)
Course & Prognosis
351(1)
28 Autoimmune Pancreatitis
352(7)
Norton J. Greenberger
General Considerations
352(1)
Clinical Findings
352(3)
Distinct Clinical and Histologic Profile
355(1)
Diagnosis and Differential Diagnosis
356(1)
Treatment
356(2)
Course & Prognosis
358(1)
29 Tumors of the Pancreas
359(12)
Julia McNabb-Baltar
Richard Swanson
Pancreatic Cancer
359(7)
Cystic Neoplasms of the Pancreas
366(4)
Pancreatic Lymphoma
370(1)
Section VII. Therapeutic Endoscopy & Diagnostic Techniques
30 Polypectomy
371(4)
Kunal Jajoo
Equipment
371(1)
Polypectomy for Sessile Polyps
372(1)
Polypectomy for Pedunculated Polyps
372(1)
Endoscopic Mucosal Resection
373(1)
Endoscopic Submucosal Dissection
373(2)
31 Acute Upper Gastrointestinal Bleeding
375(22)
John R. Saltzman
Nonvariceal Bleeding
385(5)
Less Common Causes of Nonvariceal Bleeding
390(2)
Variceal Bleeding
392(5)
32 Acute Lower Gastrointestinal Bleeding
397(9)
John R. Saltzman
Linda S. Lee
Evaluation of Lower GI Bleeding
397(5)
Specific Causes of Acute Lower GI Bleeding
402(4)
33 Endoscopic Management of Acute Biliary & Pancreatic Conditions
406(10)
Andrew C. Storm
Christopher C. Thompson
Acute Cholangitis
406(2)
Gallstone Pancreatitis
408(2)
Bile Duct Injuries
410(1)
Pancreatic Duct Injuries
411(2)
Hemorrhagic Biliary & Pancreatic Conditions
413(3)
34 Wireless Capsule Endoscopy & Deep Small Bowel Enteroscopy
416(11)
Anne C. Travis
John R. Saltzman
Capsule Endoscopy
416(8)
Deep Small Bowel Enteroscopy
424(3)
35 Gastrointestinal Foreign Bodies
427(7)
Andrew C. Storm
Christopher C. Thompson
General Considerations
427(1)
Clinical Findings
427(2)
Treatment
429(5)
36 Endoscopic Retrograde Cholangiopancreatography
434(12)
David L. Carr-Locke
Linda S. Lee
Disorders of the Major Duodenal Papilla
434(2)
Biliary System
436(5)
Pancreas
441(5)
36 Endoscopic Ultrasound
446(14)
Linda S. Lee
Cancer Staging
448(4)
Nonmalignant Lesions
452(4)
Therapeutic Endoscopic Ultrasound
456(2)
Future Directions
458(2)
Section VIII. Liver Diseases
37 Approach to the Patient with Jaundice & Abnormal Liver Tests
460(7)
Norton J. Greenberger
General Considerations
460(1)
Pathogenesis
460(1)
Clinical Findings
460(3)
Differential Diagnosis
463(2)
Diagnostic Considerations in Patients with Elevated Serum Aminotransferases
465(2)
38 Acute Liver Failure
467(13)
Sonal Kumar
Amir A. Qamar
Specific Causes of Acute Liver Failure
474(6)
39 Viral Hepatitis
480(28)
Anna Rutherford
Jules L. Dienstag
Hepatitis A
483(2)
Hepatitis B
485(10)
Hepatitis C
495(9)
Hepatitis D
504(2)
Hepatitis E
506(2)
40 Chronic Nonviral Hepatitis
508(10)
Michael P. Curry
Sanjiv Chopra
Autoimmune Hepatitis
508(5)
Wilson Disease
513(3)
α1-Antitrypsin Deficiency
516(2)
42 Hereditary Hemochromatosis
518(10)
Matthew S. Chang
Benjamin Smit
Norman D. Grace
General Considerations
518(1)
Pathogenesis
519(5)
Clinical Findings
524(2)
Treatment
526(1)
Prognosis
527(1)
43 Alcoholic Liver Disease
528(8)
Gyorgy Baffy
Tibor Krisko
General Considerations
528(1)
Pathogenesis
529(2)
Clinical Findings
531(1)
Differential Diagnosis
532(1)
Treatment
532(1)
Alcoholic Hepatitis
533(3)
44 Nonalcoholic Fatty Liver Disease
536(7)
David E. Cohen
Frank A. Anania
General Considerations
536(1)
Pathogenesis
537(1)
Clinical Findings
538(1)
Treatment
539(2)
Course & Prognosis
541(2)
45 Portal Systemic Encephalopathy & Hepatic Encephalopathy
543(6)
Norton J. Greenberger
General Considerations
543(1)
Pathogenesis
543(1)
Clinical Findings
544(2)
Treatment
546(3)
46 Ascites & Spontaneous Bacterial Peritonitis
549(8)
Norton J. Greenberger
Ascites
549(5)
Spontaneous Bacterial Peritonitis
554(3)
47 Hepatorenal Syndrome
557(5)
Norton J. Greenberger
General Considerations
557(1)
Pathogenesis
557(1)
Clinical Findings
558(1)
Acute Kidney Injury in Patients with Cirrhosis and Infection
558(1)
Differential Diagnosis
559(1)
Treatment
559(3)
48 Portal Hypertension & Esophageal Variceal Hemorrhage
562(12)
Norman D. Grace
Melissa A. Minor
Gastric Varices
572(1)
Portal Hypertensive Gastropathy
573(1)
Idiopathic Portal Hypertension
573(1)
Future Treatment Trends
573(1)
49 Drug-Induced Liver Disease
574(7)
Willis C. Maddrey
Drugs of Special Interest
578(3)
50 Liver Neoplasms
581(12)
Amir A. Qamar
Chinweike Ukomadu
Benign Liver Tumors
581(5)
Hepatocellular Carcinoma
586(5)
Cholangiocarcinoma
591(1)
Metastatic Liver Disease
592(1)
51 Liver Transplantation
593(12)
Amir A. Qamar
Indications for Transplantation
593(3)
Pretransplant Evaluation
596(1)
Contraindications
597(1)
Transplantation Procedures
597(1)
Complications
598(2)
Infection & Liver Transplantation
600(2)
Long-Term Medical Care After Liver Transplantation
602(1)
Prognosis
603(2)
52 Primary Biliary Cirrhosis
605(5)
Daniel S. Pratt
General Considerations
605(1)
Pathogenesis
605(1)
Clinical Findings
606(1)
Treatment
607(3)
Section IX. Biliary Tract Diseases
53 Primary Sclerosing Cholangitis
610(5)
Norton J. Greenberger
John R. Saltzman
General Considerations
610(1)
Clinical Findings
610(2)
Differential Diagnosis
612(1)
Treatment
612(1)
Course & Prognosis
613(2)
54 Gallstone Disease
615(11)
Gustav Paumgartner
Norton J. Greenberger
General Considerations
615(1)
Pathogenesis
616(3)
Clinical Findings
619(1)
Differential Diagnosis
620(1)
Complications
620(2)
Treatment
622(4)
Index 626
Norton J. Greenberger, MD is a Senior Attending Physician and Clinical Professor of Medicine at Harvard Medical School. Dr. Greenberger is a past President of the American Gastroenterological Association, the American College of Physicians, the Central Society for Clinical Research and the Association of Professors of Medicine. He is the author or co-author of more than 230 publications including chapters in major medical texts.

Richard S. Blumberg, MD is Professor of Medicine, Harvard Medical School Chief, Division of Gastroenterology, Hepatology and Endoscopy at Brigham and Women's Hospital.

Robert Burakoff, MD, MPH is Associate Professor of Medicine, Harvard Medical School Clinical Chief of Gastroenterology, Division of Gastroenterology, Hepatology and Endoscopy at Brigham and Women's Hospital.