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El. knyga: Current Topics In Human Genetics: Studies In Complex Diseases

Edited by (Creighton Univ Medical Center, Usa), Edited by (Univ Of Missouri-kansas City, Usa), Edited by (Windber Research Inst, Usa), Edited by (Univ Of Missouri-kansas City, Usa)
  • Formatas: 964 pages
  • Išleidimo metai: 12-Nov-2007
  • Leidėjas: World Scientific Publishing Co Pte Ltd
  • Kalba: eng
  • ISBN-13: 9789814476188
Kitos knygos pagal šią temą:
Current Topics In Human Genetics: Studies In Complex DiseasesDidesnis paveikslėlis
  • Formatas: 964 pages
  • Išleidimo metai: 12-Nov-2007
  • Leidėjas: World Scientific Publishing Co Pte Ltd
  • Kalba: eng
  • ISBN-13: 9789814476188
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The sequencing of the human genome has brought human genetics into a new era of study resulting in the generation of an explosive amount of information. Application of genomic, proteomic, and bioinformatics technologies to the study of human genetics has made it possible for human genetic diseases to be studied on an unprecedented scale, both in silico and in the wet lab. This volume provides up-to-date coverage of the broad range of research topics in this fascinating area. In the first part of the book, a whole spectrum of approaches to human genetics research is reviewed for both background and the latest progress. In the second, important topics related to genetic research of various complex human diseases are discussed. The robust content and diverse array of subjects allow the book to serve as both a concise “encyclopedia” that introduces basic and essential concepts of human genetics and an in-depth review of the current understanding of genetic research in human diseases.
Preface v
Acknowledgments vii
Regression-based Linkage Analysis Methods
1(20)
Tao Wang
Robert C. Elston
Admixture Mapping: Methods and Applications
21(16)
Xiaofeng Zhu
Survival Analysis Methods in Genetic Epidemiology
37(28)
Hongzhe Li
Genetic Association Studies: Concepts and Applications
65(30)
Jun Li
Tag SNP Selection and Its Applications in Association Studies
95(28)
Kui Zhang
Fengzhu Sun
Haplotype Inference and Association Analysis in Unrelated Samples
123(38)
Zeny Feng
Nianjun Liu
Hongyu Zhao
A Survey on Haplotyping Algorithms for Tightly Linked Markers
161(18)
Jing Li
DNA Pooling: Methods and Applications in Association Studies
179(30)
Jiexun Wang
Guohua Zou
Hongyu Zhao
Linkage Disequilibrium and Test for Interaction Between Two Loci
209(46)
Momiao Xiong
Association Tests for Complex Disease Genes While Controlling Population Stratification
255(30)
Shuanglin Zhang
Qiuying Sha
Statistical Methods for Multiple QTL Mapping in Experimental Crosses
285(40)
Daniel Shriner
Solomon Musani
Nengjun Yi
Animal Models in the Study of Genetics of Complex Human Diseases
325(26)
Weikuan Gu
Jian Yan
Yan Jiao
Acquisition of Accurate Gene Expression Information from Microarray Measurements
351(24)
Shuang Jia
Shouguo Gao
Martin J. Hessner
Xujing Wang
Application of DNA Microarray Technology in Genetics
375(22)
Jian Yan
Weikuan Gu
Yan Jiao
Expression Quantitative Trait Locus (eQTL) Mapping
397(36)
Song Huang
David Bollard
Zhreyang Wu
Hongyu Zhao
Bridging Genotype and Phenotype: Causal Pathways from DNA to Complex Traits
433(16)
Yan Cui
Functional Proteomics and Its Application in Biomedical Sciences
449(50)
Guishan Xiao
Teri Zhang
An Introduction to Biomedical Informatics
499(40)
Hai Hu
Michael N. Liebman
Protein---Protein Interactions: Concepts, Databases, Software Tools, and Biomedical Implications
539(24)
SudhaRani Mamidipalli
Jake Yue Chen
Genomic Cloning in the Postgenome Era
563(18)
Yan Jiao
Weikuan Gu
RNA Metabolism and Human Diseases
581(36)
Zhongwei Li
Gayatri Kollipara
Recent Progress in the Genetics of Osteoporosis
617(38)
Hui Shen
Yong-Jun Liu
Peng Xiao
Dong-Hai Xiong
Hong-Wen Deng
Critical Molecules in Bone Development and Genetic Bone Diseases
655(38)
Qing Wang
Ming Zhang
Tianhui Zhu
Di Chen
Genetic Factors for Human Type 1 Diabetes
693(36)
Cong-Yi Wang
Junyan Han
Jin-Xiong She
Genetic Susceptibility to Human Obesity
729(30)
Yong-Jun Liu
Hong-Wen Deng
Genes in Estrogen Metabolism Pathway and Breast Cancer
759(14)
Ji-Rong Long
Hereditary Breast and Ovarian Cancers
773(36)
Wentao Yang
Daren Shi
Jinsong Liu
Activation of Wnt Signaling in Tumor Development
809(24)
Zhimin Lu
Genetics of Autoimmune Diseases: MHC and Beyond
833(32)
Yahuan Lou
Genetics of Substance Dependence
865(18)
Joel Gelernter
Henry R. Kranzler
Insulin Resistance and Metabolic Syndrome
883(46)
Wei-Dong Li
R. Arlen Price
Genetics of Intracellular Traffic Jams: Multi-organellar Defects
929(16)
Wei Li
Author Index 945(2)
Subject Index 947
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