Atnaujinkite slapukų nuostatas

Dendrimer-Based Drug Delivery Systems: From Theory to Practice [Kietas viršelis]

Foreword by (Dendritic Sciences, Inc.,/Dendritic Nanotechologies Limited, Central Michigan University, Mt. Pleasant, Michigan, USA), Edited by
  • Formatas: Hardback, 534 pages, aukštis x plotis x storis: 234x158x33 mm, weight: 839 g
  • Serija: Wiley Series in Drug Discovery and Development
  • Išleidimo metai: 20-Jul-2012
  • Leidėjas: John Wiley & Sons Inc
  • ISBN-10: 0470460059
  • ISBN-13: 9780470460054
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 534 pages, aukštis x plotis x storis: 234x158x33 mm, weight: 839 g
  • Serija: Wiley Series in Drug Discovery and Development
  • Išleidimo metai: 20-Jul-2012
  • Leidėjas: John Wiley & Sons Inc
  • ISBN-10: 0470460059
  • ISBN-13: 9780470460054
Kitos knygos pagal šią temą:
The opportunities and challenges of using dendrimers to improve drug delivery

Among pharmaceutical and biomedical researchers, the use of dendrimers in drug delivery systems has attracted increasing interest. In particular, researchers have noted that the volume of a dendrimer increases when it has a positive charge. If this property can be applied effectively, dendrimers have enormous potential in drug delivery systems, directly supplying medication to targeted human organs.

With contributions from an international team of pioneers and experts in dendrimer research, this book provides a comprehensive overview of the latest research efforts in designing and optimizing dendrimer-based drug delivery systems. The book analyzes key issues, demonstrating the critical connections that link fundamental concepts, design, synthesis, analytical methodology, and biological assessment to the practical use of dendrimers in drug delivery applications. Topics covered include:





Dendrimer history Synthesis Physicochemical properties Principles of drug delivery Applications in diverse biomedical fields

Dendrimer-Based Drug Delivery Systems reflects the authors' thorough review and analysis of the current literature as well as their own firsthand experience in the lab. Readers will not only discover the current state of the science, but also gain valuable insights into fruitful directions for future research. References at the end of each chapter serve as a gateway to the growing body of literature in the field, enabling readers to explore each individual topic in greater depth.

Pharmaceutical and biomedical researchers will find this book a unique and essential guide to the opportunities, issues, and challenges involved in fully exploiting the potential of dendrimers to improve drug delivery.

Recenzijos

This book should be particularly valuable for everyone working in the dendrimer area, but also for researchers in drug delivery and pharmaceutical sciences more generally. To my mind, it is clearly a book to have on your shelf!.  (ChemMedChem, 1 March 2013)

Foreword vii
Donald A. Tomalia
Preface ix
Acknowledgments xi
Contributors xiii
About the Editor xvii
1 Dendrimer Chemistry: Supramolecular Perspectives and Applications
1(54)
Charles N. Moorefield
Sujith Perera
George R. Newkome
2 Physicochemical Properties of Dendrimers and Dendrimer Complexes
55(38)
Toyoko Imae
3 The Use of Dendrimers to Optimize the Physicochemical and Therapeutic Properties of Drugs
93(46)
Nicole Stieger
Wilna Liebenberg
Marique E. Aucamp
Melgardt M. de Villiers
4 Biological Properties of Phosphorus Dendrimers
139(18)
Anne-Marie Caminade
Jean-Pierre Majoral
5 Dendrimer-Based Prodrugs: Synthesis and Biological Evaluation
157(50)
Mohammad Najlah
Zhengyuan Zhou
Antony D'Emanuele
6 Improving the Biocompatibility of Dendrimers in Drug Delivery
207(32)
Yiwen Li
Libo Zhao
Yiyun Cheng
7 Degradable Dendrimers for Drug Delivery
239(68)
Marc Gingras
Myriam Roy
8 Design of Stimuli-Responsive Dendrimers for Biomedical Purposes
307(22)
Chie Kojima
9 Dendrimer-Based Gene Delivery Systems: Administration Routes and In Vivo Evaluation
329(26)
M.J. Santander-Ortega
I.F. Uchegbu
A.G. Schatzlein
10 Triazine Dendrimers for DNA and siRNA Delivery: Progress, Challenges, and Opportunities
355(52)
Meredith A. Mintzer
Olivia M. Merkel
Thomas Kissel
Eric E. Simanek
11 Dendrimer-Coated Carbohydrate Residues as Drug Delivery Trojan Horses in Glycoscience
407(32)
Yoann M. Chabre
Rene Roy
12 Nuclear Magnetic Resonance Techniques in the Analysis of Pamam Dendrimer-Based Drug Delivery Systems
439(24)
Xueyan Feng
Kun Yang
Jingjing Hu
Tongwen Xu
Yiyun Cheng
13 Dendrimer-Based Medical Nanodevices for Magnetic Resonance Imaging Applications
463(16)
Hongdong Cai
Mingwu Shen
Xiangyang Shi
14 Dendrimer-Related Nanoparticle System for Computed Tomography Imaging
479(22)
Chen Peng
Xiangyang Shi
Index 501
YIYUN CHENG, PhD, is a Full Professor of Biomedical Engineering at the School of Life Science of East China Normal University. His research interests focus on the biomedical applications of dendrimers and other dendritic polymers. Dr. Cheng has published more than forty peer-reviewed manuscripts in such journals as Nature Materials, Chemical Society Reviews, and Journal of the American Chemical Society.