Hematologists from St. Bartholomew's Hospital in London introduce an approach to differential diagnosis in their discipline that combines clinical and laboratory data to construct an overall pattern of a case. They explain how to derive patterns from peripheral blood analysis, flow cytometry immunophenotyping studies, and bone marrow examination and to use those to choose which of several possible conditions to begin treating. They include color photomicrographs as an atlas of common and more unusual cases. The accompanying disc contains data and final diagnoses for the more than 200 real cases cited in the text. The approach should be of use to hematologists and hematopathologists, especially those interpreting the three measures, and for technologists and laboratory staff screening full blood counts. Distributed by Oxford U. Press. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Diagnostic Hematology is a comprehensive guide to the laboratory diagnosis of blood and bone marrow diseases, including the use of flow cytometry for immunologic subclassification of leukemias and lymphomas. It presents a logical and systematic approach to diagnosis, based on the patterns derived from peripheral blood analysis, flow cytometry immunophenotyping studies and bone marrow examination. The book presents each diagnostic problem as it would be investigated in practice and takes the reader step-by-step through the process of reaching the differential diagnosis. It gives advice on the proper approach to diagnostic work-up and on how to avoid common diagnostic pitfalls. The patterns formed by different blood and bone marrow disorders are described in detail and illustrated with color photomicrographs and flow cytometry graphics. A free companion CD-ROM featuring 200 actual cases allows the user to assess real test results and see the patterns which lead to the final interpretation in each case.
Diagnostic hematology is a problem-solving process involving the gathering and analysis of the relevant findings in each case. Based on the combination of clinical and laboratory data, an experienced diagnostician can formulate the overall 'pattern' of a case. The 'pattern approach' to differential diagnosis is an integral component of the diagnostic reasoning of many expert hematologists.
In this unique textbook the authors present a logical and systematic approach to diagnosis, based on the patterns derived from peripheral blood analysis, flow cytometry immunophenotyping studies and bone marrow examination. Unlike standard textbooks which are organized by specific diseases and thereby assume the reader has reached a diagnosis, this text presents the diagnostic problem as it is investigated in practice.
The patterns formed by different blood and bone marrow disorders are described in detail and illustrated with color photomicrographs, or flow cytometry graphics. The reader is taken through the process of reaching the differential diagnosis. Advice is given on the proper approach to diagnostic work-up and how to avoid common diagnostic pitfalls. The companion CD-ROM, with full instructions given in the appendix, offers the reader the chance to assess real test results, and see the patterns which lead to the final interpretation in over 200 cases.
As a result the reader will develop the skill of pattern recognition and be able to incorporate this diagnostic approach in practice. This is an essential text for physicians practicing hematology and hematopathology, especially those interpreting peripheral blood, flow cytometry and bone marrow specimens; also for technologists and laboratory staff responsible for the screening of full blood counts, the initial review of blood/bone marrow films or immunophenotyping data.
System requirements: Windows 95, Windows 98 or Windows NT. Screen resolution of 800 x 600 with 16 million colours (24-bit). Minimum display: at least 65,000 colours (16-bit).
