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El. knyga: Diagnostic Pathology: Breast, E-Book: Diagnostic Pathology: Breast, E-Book

(Former Chief of Breast Pathology Services, Brigham and Women's Hospital, Associate Professor, Harvard Medical School, Boston, Massachusetts, USA), (Professor and Director of IHC-ISH Laboratory and Breast Subspecialty Service, Universit)
  • Formatas: EPUB+DRM
  • Serija: Diagnostic Pathology
  • Išleidimo metai: 19-Feb-2021
  • Leidėjas: Elsevier - Health Sciences Division
  • Kalba: eng
  • ISBN-13: 9780323758963
Kitos knygos pagal šią temą:
  • Formatas: EPUB+DRM
  • Serija: Diagnostic Pathology
  • Išleidimo metai: 19-Feb-2021
  • Leidėjas: Elsevier - Health Sciences Division
  • Kalba: eng
  • ISBN-13: 9780323758963
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This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of breast pathology, it incorporates the most recent clinical, pathological, radiological, staging, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Breast is a one-stop reference for accurate, complete surgical pathology evaluation-ideal as a day-to-day reference or as a reliable training resource.

Includes a wide range of new information on breast pathology, including material specific to core needle biopsies, to help you identify, diagnose, and manage disease 



Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays 



Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer 



Features new chapters covering gene expression profiling; immunotherapy; the differential diagnosis for common histologic patterns; solid papillary carcinoma; acinic cell carcinoma; and intraoperative consultations, including a video showing how to process specimens with radioactive seeds 



Offers expert guidance on evaluation of postneoadjuvant resection specimens, sentinel lymph nodes, and extent of disease and multifocality 



Contains thousands of extensively annotated images, including gross pathology photographs, histopathology photomicrographs with a wide range of immunohistochemical stains, fluorescent in situ hybridization, and full-color illustrations 



Features a templated, highly formatted design; concise, bulleted text; diagnostic pearls; key facts in each chapter; and an extensive index for easy reference 



Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices 
SECTION 1 NORMAL BREAST
Histology of Normal Breast
4(10)
David G. Hicks
Susan C. Lester
Breast Life Cycle Changes
14(8)
David G. Hicks
Susan C. Lester
SECTION 2 BREAST SPECIMENS, PROCESSIONG
Breast Specimens: General Considerations
22(6)
David C. Hicks
Susan C. Lester
Core Needle Biopsies
28(12)
David G. Hicks
Susan C. Lester
Excisions
40(6)
David G. Hicks
Susan C. Lester
Margins and Reexcisions
46(6)
David G. Hicks
Susan C. Lester
Mastectomies
52(6)
David G. Hicks
Susan C. Lester
Reduction Mammoplasties
58(4)
David G. Hicks
Susan C. Lester
Intraoperative Consultation
62(12)
David G. Hicks
Susan C. Lester
Beth T. Harrison
SECTION 3 DIAGNOSTIC PATTERNS
Overview of Papillary Lesions
74(10)
David G. Hicks
Susan C. Lester
Overview of Spindle Cell Lesions
84(8)
David G. Hicks
Susan C. Lester
Overview of Small Acinar Proliferations
92(10)
David G. Hicks
Susan C. Lester
Overview of Epithelial/Myoepithelial Lesions
102(10)
David G. Hicks
Susan C. Lester
SECTION 4 DISORDERS OF DEVELOPMENT
Juvenile Papillomatosis
112(2)
David G. Hicks
Susan C. Lester
Gynecomastia in Men and Gynecomastia-Like Changes in Women
114(4)
David G. Hicks
Susan C. Lester
Hamartoma (Fibroadenolipoma)
118(6)
David G. Hicks
Susan C. Lester
SECTION 5 BENING EPITHELIAL LESIONS
Epidemiology: Lesions Conferring Increased Risk of Breast Carcinoma
124(6)
David G. Hicks
Susan C. Lester
Nonproliferative Changes
130(4)
David G. Hicks
Susan C. Lester
Columnar Cell Change, Columnar Cell Hyperplasia, and Flat Epithelial Atypia
134(6)
David G. Hicks
Susan C. Lester
Mucocele-Like Lesions
140(4)
David G. Hicks
Susan C. Lester
Collagenous Spherulosis
144(4)
David G. Hicks
Susan C. Lester
Syringomatous Tumor of the Nipple
148(6)
David G. Hicks
Susan C. Lester
Sclerosing Adenosis
154(8)
David G. Hicks
Susan C. Lester
Usual Ductal Hyperplasia
162(4)
David G. Hicks
Susan C. Lester
Radial Sclerosing Lesion/Radial Scar
166(6)
David G. Hicks
Susan C. Lester
Papilloma, Large Duct and Small Duct
172(8)
David G. Hicks
Susan C. Lester
Nipple Adenoma
180(6)
David G. Hicks
Susan C. Lester
Microglandular Adenosis
186(8)
David G. Hicks
Susan C. Lester
Atypical Ductal Hyperplasia
194(8)
David G. Hicks
Susan C. Lester
Atypical Lobular Hyperplasia
202(6)
David G. Hicks
Susan C. Lester
Adenomyoepithelioma
208(10)
David G. Hicks
Susan C. Lester
SECTION 6 CARCINOMAS
Risk Factors for Developing Breast Carcinoma
218(6)
David G. Hicks
Susan C. Lester
CARCINOMA IN SITU
Lobular Carcinoma In Situ
224(10)
David G. Hicks
Susan C. Lester
Ductal Carcinoma In Situ
234(14)
David G. Hicks
Susan C. Lester
Ductal Carcinoma In Situ, Paget Disease
248(10)
David G. Hicks
Susan C. Lester
Microinvasive Carcinoma
258(6)
David G. Hicks
Susan C. Lester
Encapsulated Papillary Carcinoma
264(6)
David G. Hicks
Susan C. Lester
Solid Papillary Carcinoma
270(6)
David G. Hicks
Susan C. Lester
TYPES OF INVASIVE CARCINOMA
Invasive Breast Carcinoma of No Special Type (Ductal)
276(8)
David G. Hicks
Susan C. Lester
Invasive Lobular Carcinoma
284(12)
David G. Hicks
Susan C. Lester
Tubular/Cribriform Carcinoma
296(8)
David G. Hicks
Susan C. Lester
Mucinous (Colloid) Carcinoma
304(10)
David G. Hicks
Susan C. Lester
Invasive Papillary Carcinoma
314(2)
David G. Hicks
Susan C. Lester
Invasive Micropapillary Carcinoma
316(8)
David G. Hicks
Susan C. Lester
Metaplastic Carcinoma
324(10)
David G. Hicks
Susan C. Lester
Low-Crade Adenosquamous Carcinoma
334(8)
David G. Hicks
Susan C. Lester
Triple Negative and Basal-Like Carcinomas
342(8)
David G. Hicks
Susan C. Lester
Adenoid Cystic Carcinoma
350(12)
David G. Hicks
Susan C. Lester
Secretory Carcinoma
362(6)
David G. Hicks
Susan C. Lester
HER2(+) Carcinoma
368(8)
David G. Hicks
Susan C. Lester
Inflammatory Carcinoma
376(6)
David G. Hicks
Susan C. Lester
Invasive Apocrine Carcinoma
382(6)
David G. Hicks
Susan C. Lester
Invasive Neuroendocrine Carcinoma
388(8)
David G. Hicks
Susan C. Lester
Invasive Carcinoma With Osteoclast-Like Giant Cells
396(2)
David G. Hicks
Susan C. Lester
Carcinoma With Extensive Intraductal Component
398(6)
David G. Hicks
Susan C. Lester
SECTION 7 PROGNOSTIC AND PREDICTIVE FACTORS
Introduction: Prognostic and Predictive Factors
404(6)
David G. Hicks
Susan C. Lester
AJCC Breast Cancer Staging
410(8)
David G. Hicks
Susan C. Lester
Locally Advanced Breast Cancer
418(4)
David G. Hicks
Susan C. Lester
ANATOMIC FACTORS
Locally Recurrent Carcinoma
422(6)
David G. Hicks
Susan C. Lester
Neoadjuvant Therapy
428(10)
David G. Hicks
Susan C. Lester
Histologic Grade
438(6)
David G. Hicks
Susan C. Lester
Lymph Node Metastases
444(12)
David G. Hicks
Susan C. Lester
Lymphovascular Invasion
456(8)
David G. Hicks
Susan C. Lester
Size and Multiple Foci
464(4)
David G. Hicks
Susan C. Lester
MOLECULAR FACTORS
Hormone Receptors (ER/PR)
468(10)
David G. Hicks
Susan C. Lester
HER2 Evaluation
478(14)
David G. Hicks
Susan C. Lester
DNA Analysis
492(4)
David G. Hicks
Susan C. Lester
Circulating Tumor Cells and Circulating Tumor DNA
496(4)
David G. Hicks
Susan C. Lester
Immunotherapy: Markers
500(4)
David G. Hicks
Susan C. Lester
Expression Profiling, mRNA
504(6)
David G. Hicks
Susan C. Lester
Expression Profiling, Oncotype DX Assay
510(4)
David G. Hicks
Susan C. Lester
Expression Profiling, MammaPrint Assay
514(2)
David G. Hicks
Susan C. Lester
Expression Profiling, Prosigna (NanoString)/PAM50
516(2)
David G. Hicks
Susan C. Lester
Expression Profiling, Protein
518(8)
David G. Hicks
Susan C. Lester
Expression Profiling, EndoPredict
526(4)
David G. Hicks
Susan C. Lester
SECTION 8 STROMAL LESIONS
Fibroadenoma
530(8)
David G. Hicks
Susan C. Lester
Phyllodes Tumor
538(10)
David G. Hicks
Susan C. Lester
Pseudoangiomatous Stromal Hyperplasia
548(4)
David G. Hicks
Susan C. Lester
Myofibroblastoma
552(8)
David G. Hicks
Susan C. Lester
Lipoma and Angiolipoma
560(4)
David G. Hicks
Susan C. Lester
Diabetic Mastopathy/Lymphocytic Mastopathy
564(4)
David G. Hicks
Susan C. Lester
Granular Cell Tumor
568(6)
David G. Hicks
Susan C. Lester
Nodular Fasciitis
574(6)
David G. Hicks
Susan C. Lester
Fibromatosis
580(8)
David G. Hicks
Susan C. Lester
Hemangiomas
588(6)
David G. Hicks
Susan C. Lester
Papillary Endothelial Hyperplasia
594(2)
David G. Hicks
Susan C. Lester
Atypical Vascular Lesions of Skin
596(4)
David G. Hicks
Susan C. Lester
Angiosarcoma
600(10)
David G. Hicks
Susan C. Lester
Sarcomas
610(8)
David G. Hicks
Susan C. Lester
SECTION 9 INFLAMMATORY LESIONS
Lactational Abscess
618(2)
David G. Hicks
Susan C. Lester
Nonlactationat Abscess
620(8)
David G. Hicks
Susan C. Lester
Fat Necrosis
628(4)
David G. Hicks
Susan C. Lester
Duct Ectasia
632(2)
David G. Hicks
Susan C. Lester
Squamous Metaplasia of Lactiferous Ducts
634(6)
David G. Hicks
Susan C. Lester
Implant Pathology
640(8)
David G. Hicks
Susan C. Lester
Sarcoidosis
648(2)
David G. Hicks
Susan C. Lester
Amyloid of the Breast
650(2)
David G. Hicks
Susan C. Lester
Lupus Mastitis
652(2)
David G. Hicks
Susan C. Lester
IgC4-Related Sclerosing Mastitis
654(6)
David G. Hicks
Susan C. Lester
SECTION 10 OTHER TYPES OF MALIGNANCIES
Metastases to Breast
660(6)
David C. Hicks
Susan C. Lester
Lymphoma
666(12)
David G. Hicks
Susan C. Lester
SECTION 11 HEREDITARY BREAST DISEASE
Hereditary Breast Cancer
678(8)
David G. Hicks
Susan C. Lester
Germline Mutations Conferring Increased Risk of
686(2)
Breast Cancer: Tables David G. Hicks
Susan C. Lester
Breast/Ovarian Cancer Syndrome: BRCA1
688(6)
David G. Hicks
Susan C. Lester
Breast/Ovarian Cancer Syndrome: BRCA2
694(4)
David G. Hicks
Susan C. Lester
Li-Fraumeni Syndrome
698(8)
David G. Hicks
Susan C. Lester
SECTION 12 UNUSUAL PRESENTATIONS OF BREAST LESIONS
Breast Carcinoma, Male
706(4)
David G. Hicks
Susan C. Lester
Iatrogenic Changes
710
David G. Hicks
Susan C. Lester
Susan C. Lester, MD, PhD, is the Former Chief of Breast Pathology Services at Brigham and Women's Hospital and Associate Professor with Harvard Medical School in Boston, Massachusetts. David G. Hicks, MD, is a professor and director of the IHC-ISH Laboratory and Breast Subspecialty Service at the University of Rochester Medical Center in Rochester, New York.