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Discovery and Synthesis of Crop Protection Products [Kietas viršelis]

Edited by (Research Chemist, DuPont Crop Protection), Edited by (Research Portfolio Manager, Insectisides and Seed Care, Syngenta Crop Protection AG)
  • Formatas: Hardback, 480 pages, aukštis x plotis x storis: 231x163x30 mm, weight: 818 g, 86
  • Serija: ACS Symposium Series
  • Išleidimo metai: 30-Jun-2016
  • Leidėjas: Oxford University Press Inc
  • ISBN-10: 0841231028
  • ISBN-13: 9780841231023
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 480 pages, aukštis x plotis x storis: 231x163x30 mm, weight: 818 g, 86
  • Serija: ACS Symposium Series
  • Išleidimo metai: 30-Jun-2016
  • Leidėjas: Oxford University Press Inc
  • ISBN-10: 0841231028
  • ISBN-13: 9780841231023
Kitos knygos pagal šią temą:
Modern agribusiness is one of the main generators of employment and income worldwide and plays a vital role in improving the production, quality, and quantity of food, feed, fiber, and fuel ensuring our world has the safest and most nutritious, abundant, and sustainable food supply possible. The global agribusiness industry with its offerings such as insecticides, herbicides, and fungicides as well as biotechnology products contributes to growing public expectations for food security and agricultural sustainability while addressing the industry's global challenges, such as population growth and rising caloric consumption, increasing environmental stresses across the globe, a changing regulatory landscape, development of resistance to existing active ingredients and traits by investing in effective R&D programs and inventing new solutions.

The book provides an update on state of the art crop protection research and highlights the pivotal role of novel chemistries for modern crop protection. Recent research and new directions in the synthesis and chemistry of agrochemicals, as well as new research approaches, tools and directions in the crop protection field including nematicides, biologicals and natural products are described and details on the design, synthesis, biology and/or structure-activity relationships of a series of new chemical entities targeting fungicides, insecticides, herbicides and nematicides provided. Furthermore future directions for advancing research and regulation of agricultural chemistry and pest management science, promoting public health, and preserving environmental quality are covered as well.
Preface xi
1 Modern Agribusiness - Markets, Companies, Benefits and Challenges
1(14)
Peter Maienfisch
Thomas M. Stevenson
2 Building a Successful Crop Protection Pipeline: Molecular Starting Points for Discovery
15(10)
Kathleen A. Shelton
George P. Lahm
3 New Paradigms in Crop Protection Research: Registrability and Cost of Goods
25(14)
Camilla Corsi
Clemens Lamberth
4 Pesticide Invention Model in a Japanese Company
39(16)
Noriyasu Sakamoto
5 Natural Products for Crop Protection: Evolution or Intelligent Design
55(8)
Scott H. Hutchins
6 Leveraging Mammalian Therapeutic Research To Identify Novel Lead Chemistries for Crop Protection
63(16)
James E. Hunter
Michael Loso
Francis E. Tisdell
Maurice C. H. Yap
7 Discovery of New Herbicide Modes of Action with Natural Phytotoxins
79(14)
Stephen O. Duke
Franck E. Dayan
8 What Makes a Good Compound against Sucking Pests?
93(18)
Anke Buchholz
Anthony C. O'Sullivan
Stefan Trapp
9 Plant- or Fungal-Produced Conophthorin as an Important Component of Host Plant Volatile-Based Attractants for Agricultural Lepidopteran Insect Pests
111(18)
John J. Beck
Bradley S. Higbee
10 Tioxazafen: A New Broad-Spectrum Seed Treatment Nematicide
129(20)
Urszula Slomczynska
Michael S. South
Greg J. Bunkers
Donald Edgecomb
Dawn Wyse-Pester
Shaun Selness
Yiwei Ding
Jessica Christiansen
Kent Ediger
William Miller
Pana Charumilind
Gregory Hartmann
Jeremy Williams
Matthew Dimmic
Barry Shortt
William Haakenson
Al Wideman
Michael Crawford
Michelle Hresko
James McCarter
11 The Discovery of Oxathiapiprolin: A New, Highly-Active Oomycete Fungicide with a Novel Site of Action
149(14)
Robert J. Pasteris
Mary Ann Hanagan
John J. Bisaha
Bruce L. Finkelstein
Lisa E. Hoffman
Vann Gregory
Christopher P. Shepherd
John L. Andreassi
James A. Sweigard
Boris A. Klyashchitsky
Yewande T. Henry
Richard A. Berger
12 Novel Substituted Anilinopyrimidine Compounds: Design, Synthesis, and Fungicidal Activity
163(12)
Jichun Yang
Baoshan Chai
Huichao Li
Zhinian Li
Changling Liu
13 Succinate Dehydrogenase: An Ideal Target for Fungicide Discovery
175(20)
Li Xiong
Yan-Qing Shen
Li-Na Jiang
Xiao-Lei Zhu
Wen-Chao Yang
Wei Huang
Guang-Fu Yang
14 Mollisin: A Promising Antifungal Natural Product
195(10)
Christian Winter
Christine Wiebe
15 Combinatorial Approach To Lead Generation and the Discovery of a Potent Septoria tritici Fungicide
205(14)
Z. L. Benko
G. E. Davis
D. H. Young
W. J. Owen
B. A. Lorsbach
16 HPPD Herbicide-Safener Combinations as Resistance Breaking Solutions for 21st Century Agriculture
219(14)
Stephen Lindell
Christopher Rosinger
Monika Schmitt
Harry Strek
Andreas van Almsick
Lothar Willms
17 Indaziflam: An Innovative Broad Spectrum Herbicide
233(14)
Hartmut Ahrens
18 Discovery and SAR of Halauxifen Methyl: A Novel Auxin Herbicide
247(14)
Paul R. Schmitzer
Terry W. Balko
John F. Daeuble
Jeffrey B. Epp
Norbert M. Satchivi
Thomas L. Siddall
Monte R. Weimer
Carla N. Yerkes
19 3-Sulfonylisoxazoline Derivatives as Novel Herbicides
261(16)
Minora Ito
Masao Nakatani
Makoto Fujinami
Ryo Hanai
20 Broad-Spectrum PPO-Inhibiting N-Phenoxyphenyluracil Acetal Ester Herbicides
277(14)
Thomas P. Selby
Marc Ruggiero
Wonpyo Hong
D. Andrew Travis
Andrew D. Satterfield
Amy X. Ding
21 New Approaches to the Design and Synthesis of Inhibitors of Acetyl-CoA Carboxylase
291(14)
James N. Scutt
Stephane A. M. Jeanmart
Christopher J. Mathews
Michel Muehlebach
Tomas Smejkal
Stephen C. Smith
Helmars Smits
J. Steven Wailes
William G. Whittingham
Nigel J. Willetts
22 4-Azolyl-5-Hydroxy Pyridazinones: Potent Grass Herbicides
305(12)
Thomas M. Stevenson
Teodorica M. Cenizal
Eric A. Marshall
King Mo Sun
Andrew E. Taggi
Martin J. Currie
Patrick L. Rardon
23 Chemical Control of Root Parasitic Weeds
317(14)
Atsushi Okazawa
Takatoshi Wakabayashi
24 Sivanto® - A Novel Insecticide with a Sustainable Profile
331(14)
Peter Jeschke
Matthias Haas
Ralf Nauen
Oliver Gutbrod
Michael Edmund Beck
Svend Matthiesen
Robert Velten
25 Pharmacophore Based Design and Synthesis of Novel Neonicotinic Insecticides
345(20)
Z. L. Benko
D. A. Demeter
C. V. DeAmicis
W. R. Erickson
G. B. Watson
26 Triflumezopyrim: Discovery and Optimization of a Mesoionic Insecticide for Rice
365(14)
Caleb W. Holyoke, Jr.
Wenming Zhang
Thomas F. Pahutski, Jr.
George P. Lahm
My-Hanh Thi Tong
Daniel Cordova
Mark E. Schroeder
Eric A. Benner
James J. Rauh
Robert F. Dietrich
Robert M. Leighty
Robert F. Daly
Rejane M. Smith
Daniel R. Vincent
Laurie A. Christianson
27 Synthesis and Biological Activity of a Novel Acaricide, Pyflubumide
379(12)
Takashi Furuya
Motofumi Nakano
Akiyuki Suwa
Noriaki Yasokawa
Shinsuke Fujioka
Kozo Machiya
28 Synthesis and Insecticidal Activity of New 2-Aryl-3,5-dihydro-2H-1,4-Benzoxazepine Derivatives
391(20)
Jerome Cassayre
Ottmar Huter
Dave Hughes
Anthony O'Sullivan
Wayne Craig
Olivier Jacob
Eric Clarke
Fergus Earley
Anja Schade
29 Synthesis and Insecticidal Activity of New Benzyl- and Indanyl-Oxazolines, Thiazolines and Alkoxy-Alkyl-Imidazolines
411(20)
Anthony C. O'Sullivan
Juergen H. Schaetzer
Christophe Luethy
Christopher J. Mathews
Clare Elliott
Thomas Pitterna
Jagadish Pabba
Olivier Jacob
Anke Buchholz
Judith Blythe
30 Multiple Sites of Insecticidal Action in Ionotropic GABA Receptors
431(16)
Yoshihisa Ozoe
Fumiyo Ozoe
Tomo Kita
Mohammad Mostafizur Rahman
Genyan Liu
Kazutoshi Hisano
Madoka Takashima
Yunosuke Nakata
31 Insect Voltage-Gated Chloride Channels as a Possible Insecticide Target Site
447(8)
Lacey J. Jenson
Troy D. Anderson
Jeffrey R. Bloomquist
Editors' Biographies
455(4)
Indexes
Author Index
459(2)
Subject Index
461
Dr. Peter Maienfisch, Research Portfolio Manager Insecticides & Seedcare, studied chemistry at the ETH in Zürich, Switzerland, where he received his PhD in 1983. After a post-doctoral stay at Caltech (Pasadena, CA, USA) Peter joined Ciba-Geigy in Basel in 1984. In 2015, he became Honorary Professor of the East China University of Science and Technology (ECUST), Shanghai, China. Furthermore he is the inventor of thiamethoxam (Actara®, Cruiser®, one of the leading insecticides world-wide) and is a member of the Swiss & American Chemical Societies and the CHIMIA Editorial Board.

Dr. Thomas M. Stevenson graduated with a B.S. in chemistry from Saint Louis University in 1979 where he carried out undergraduate research with Harold A. Dieck funded by a Monsanto Summer Fellowship. He received a Ph.D. in organic chemistry from the University of Illinois in 1983, under the supervision of Nelson J. Leonard. After postdoctoral research at the University of Geneva from 1983 to 1985 with Wolfgang Oppolzer, Stevenson joined DuPont Crop Protection as a research chemist, rising in ranks to his current position as senior research fellow