Dupuytren's Disease: A Scientific Review offers consolidated, up-to-date coverage of both the basic normal (nonpathologic) science and cutting-edge science of this progressive disorder. Drs. Lawrence C. Hurst, Marie A. Badalamente, and David Edward Komatsu break down the complex topic of Dupuytrens contracture into its basic scientific components. Hand surgeons, plastic surgeons, and orthopaedic surgeons will find this unique, concise title to be especially helpful in their practices.
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Includes chapters on prevalence of Dupuytren's disease, normal genetics and the genetic abnormalities associated with Dupuytren's disease, and collagen and collagen synthesis in healthy fascia and Dupuytren's disease.
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Provides numerous illustrations throughout.
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Contains an in-depth bibliography and a useful, complete glossary of related terms.
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Consolidates today's available information on Dupuytrens science into a single, convenient resource.
1. Incidence and prevalence of Dupuytrens disease
2. Epidemiology and risk factors in Dupuytren's disease
3. Anatomy and pathoanatomy in Dupuytren's disease
4. Genetics of Dupuytrens disease
5. Cells of Dupuytrens disease
6. Growth factors, hormones, cytokines, and free radicals in Dupuytrens
disease
7. MicroRNAs in Dupuytren's disease
8. Signaling pathways in Dupuytrens disease
9. Collagen and collagen synthesis in Dupuytrens disease
10. Collagenase
11. Extracellular matrix in Dupuytrens disease
12. Developing new therapeutics for Dupuytrens disease
