Although theoretically an ideal form of treatment, hemodiafiltration (HDF) has not been widely used because it was considered to be impractical. However, the increasing sophistication of HDF techniques - on-line HDF and push/pull HDF - has made this form of treatment a viable alternative to conventional hemodialysis (HD). The present volume describes the new developments and evaluates their clinical effectiveness. A section of the book is also devoted to the related technique of acetate-free biofiltration. The advantages of HDF over HD in the therapy of a number of conditions are also discussed. Beneficial effects are demonstrated, for example, for joint pain, restless legs syndrome, pruritus and insomnia. Bringing together the experience of leading specialists, the book will be appreciated by all those concerned to optimize dialysis treatment.
Part 1 On-line hemodiafiltration: a decade of experience with on-line
hemofiltration/hemodiafiltration, J. Sternby; hemodiafiltration with on-line
production of substitution fluid - long-term safety and quantitative
assessment of efficacy, B. Canaud et al; characteristics of protein removal
in hemodiafiltration, S.-T. Kim; comparison of types of on-line HDF from the
standpoint of low molecular weight protein removal, M. Ono et al. Part 2
Push/pull hemodiafiltration: efforts to reduce the endotoxin levels in
dialysate, T. Takamiya; importance of convection in artificial kidney
treatment, N.J. Ofsthun and A.L. Zydney; a simple method for clinical
application of push/pull hemodiafiltration, K. Tsuruta et al; newly developed
economical and efficient push/pull hemodiafiltration, T. Shinzato et al. Part
3 Acetate-free biofiltration: acetate-free biofiltration - state of the art,
N.K. Man et al; acetate-free biofiltration - the lessons we learned from 8
years' experience, B. Perrone; acetate-free biofiltration - acidosis
correction and cardiovascular stability, P. Zucchelli et al; correction of
metabolic acidosis and changes in plasma acetate levels in acetate and
bicarbonate dialyses and acetate-free biofiltration, M. Suzuki and Y.
Hirasawa; clinical advantages of acetate-free biofiltration, T. Kuno et al.
