In its 2nd Edition, this book offers valuable insight into current developments in cardiac electrophysiology and clinical electrocardiology. Covers established and evidence-based knowledge of clinical outcomes, areas of controversy and future research trends.
Electrical Disease of the Heart, 2nd Edition, volume 1, provides a valuable insight to the latest developments in the field of cardiac electrophysiology and clinical electrocardiology. Each chapter includes up-to-date results of studies aimed at providing an understanding of the electrical function of the heart in health and disease, established and evidence-based knowledge of clinical outcomes, areas of controversy, and future trends. This book is highly relevant to a broad audience, ranging from medical and graduate students, to clinicians and scientists.
Basic Cardiac Electrophysiology- Promises Kept and Promises to Keep.-
Basic Physiology of Ion Channel Function.- Developmental Aspects of the
Electrophysiology of the Heart: Function Follows Form.- Anatomic and
Histopathologic Characteristics of the Conductive Tissues of the Heart.-
Neural Regulation of the Heart in Health and Disease.- Mechanisms of Cardiac
Arrhythmia.- Mechanisms of Action of Antiarrhythmic Drugs in Ventricular
Arrhythmias.- Mechanisms of Action of Antiarrhythmic Drugs in Atrial
Fibrillation.- Mechano-Electrical Interactions and their Role in Electrical
Function of the Heart.- Pathological Roles of the Cardiac Sodium Channel Late
Current (late INa).- Sodium Ion Channelopathies.- L-Type Calcium Channel
Disease.- Nerve Sprouting, Defibrillation and Calcium Waves.- K+
Channelopathies (IKs, IKr, and Ito).- Cardiac ATP-Sensitive Potassium
Channels and Associated Channelopathies.- Cardiac KATP Channels in Health and
Diseases.- Ca2+ Release Channels (Ryanodine Receptors) and Arrhythmogenesis.-
Caveolae and Arrhythmogenesis.- Senescence and Arrhythmogenesis.- Comparisons
of Substrates Responsible for Atrial versus Ventricular Fibrillation.- Single
Nucleotide Polymorphisms in Health and Cardiac Disease.- Electrophysiological
Remodeling in Heart Failure.- Ventricular Electrical Remodeling in
Compensated Cardiac Hypertrophy.- Physiological and Other Biological
Pacemakers.- Cardiac Memory: From Electrical Curiosity to Clinical Diagnostic
and Research Tool.- Heritable Arrhythmogenic Channelopathies, Primary
Electrical Diseases, and Sudden Cardiac Death.- Celebrating the Challenge of
Cardiac Arrhythmias.- Congenital Long QT Syndrome.- Brugada Syndrome
Clinical and Genetic Aspects.- Brugada Syndrome: Cellular Mechanisms and
Approaches to Therapy.- Early Repolarization Syndrome: Epidemiology,
Genetics, and Risk Stratification.- Catecholaminergic Polymorphic
VentricularTachycardia.- Andersen-Tawil and Timothy Syndromes.- Short QT
Syndrome.- Progressive Cardiac Conduction Disease.- Genetics of Atrial
Fibrillation.- Idiopathic Ventricular Fibrillation.
Ihor Gussak, MD, PhD, Charles Antzelevitch, PhD, FACC, FAHA, FHRS, Arthur A.M. Wilde, MD, PhD, Brian D. Powell, MD, Michael J. Ackerman, MD, PhD and Win-Kuang Shen, MD
