Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports on work done with carcinogenic metals and the mechanisms of their carcinogenicity, including Arsenic and Chromate. Chapters in this release include Breast cancer carcinogenesis by organophosphate pesticides, Polyadenylation of Canonical histone H3.1 in Carcinogenesis, Epigenomic reprogramming in iAs-mediated carcinogenesis, MicroRNAs and epigenetic regulation in metal-induced angiogenesis and carcinogenesis, Environmental epigenetics and new mechanistic markers of chemical exposure, Arsenic carcinogenesis by inhibition of DNA repair, Genetic and environmental reprogramming of the sarcoma epigenome, Mechanism of chromate carcinogenesis by chromatin alterations, and more.
Other chapters cover Arsenic carcinogenesis and microRNAs, Epigenetic mechanism of Cr(VI)-induced cell malignant transformation and tumorigenesis, The dark side of NRF2 in arsenic carcinogenesis, and Chemical mechanisms of DNA damage by carcinogenic chromium(VI).
Preface
Max Costa
1. Mechanisms of chromate carcinogenesis by chromatin alterations
Hesbon A. Zablon, Andrew VonHandorf and Alvaro Puga
2. Chemical mechanisms of DNA damage by carcinogenic chromium(VI)
Casey Krawic and Anatoly Zhitkovich
3. The dark side of NRF2 in arsenic carcinogenesis
Matthew Dodson, Jinjing Chen, Aryatara Shakya, Annadurai Anandhan and Donna
D. Zhang
4. Breast carcinogenesis induced by organophosphorous pesticides
Gloria M. Calaf
5. Tungsten toxicity and carcinogenesis
Alicia M. Bolt
6. Arsenic and cancer: Evidence and mechanisms
Rachel M. Speer, Xixi Zhou, Lindsay B. Volk, Ke Jian Liu and Laurie G.
Hudson
7. miRNAs and arsenic-induced carcinogenesis
Alexandra N. Nail, Ana P. Ferragut Cardoso, Lakyn K. Montero and J.
Christopher States
8. Epigenetic and epitranscriptomic mechanisms of chromium carcinogenesis
Zhishan Wang and Chengfeng Yang
9. Polyadenylation of canonical histone H3.1 in carcinogenesis
Arul Veerappan, Aikaterini Stavrou and Max Costa
10. Genetic and environmental reprogramming of the sarcoma epigenome
Anne GrandMaison, Rachael Kohrn, Emmanuel Omole, Mahek Shah, Peter Fiorica,
Jennie Sims and Joyce E. Ohm
11. Epigenomic reprogramming in iAs-mediated carcinogenesis
Smitha George, Richard N. Cassidy, Wesley N. Saintilnord and Yvonne
Fondufe-Mittendorf
Professor Max Costa's research interests include molecular mechanisms of metal carcinogenesis, cancer, pharmacology, epigenetics, and chromatin structure. Dr. Costa has published over 380 papers and has authored a book on Metal Carcinogenesis Testing. He serves on the Editorial Board as an Associate Editor for the Elsevier Journal, Toxicology and Applied Pharmacology.
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