| Section 1: Clinical Chemistry And Other Laboratory Tests |
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1 Basic Principles of Laboratory Medicine |
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3 | (13) |
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3 | (5) |
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8 | (1) |
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8 | (1) |
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Gaussian Distribution and Reference Ranges |
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8 | (1) |
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Interpretation of Laboratory Tests |
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8 | (1) |
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Test Performance Specifications |
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9 | (1) |
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Diagnostic Value of a Test |
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10 | (1) |
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11 | (1) |
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12 | (1) |
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Credentials of a Laboratory |
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13 | (1) |
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13 | (1) |
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Safety in the Clinical Laboratory |
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14 | (2) |
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16 | (26) |
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Composition of Normal Urine |
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16 | (1) |
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Indications for Urinalysis |
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16 | (1) |
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16 | (1) |
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Changes Which Occur in Standing Urine at Room Temperature |
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17 | (1) |
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18 | (2) |
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20 | (13) |
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33 | (9) |
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42 | (12) |
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Structure and Function of Kidney |
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42 | (2) |
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Factors Affecting Renal Function |
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44 | (1) |
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Indications for Renal Function Tests |
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44 | (1) |
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Classification of Renal Function Tests |
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44 | (1) |
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Tests to Evaluate Glomerular Function |
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45 | (4) |
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Tests to Evaluate Tubular Function |
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49 | (2) |
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51 | (3) |
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4 Laboratory Tests in Diabetes Mellitus |
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54 | (12) |
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Metabolic Actions of Insulin |
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54 | (1) |
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Classification of Diabetes Mellitus |
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54 | (3) |
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57 | (1) |
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Metabolic Alterations in Diabetes Mellitus |
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57 | (1) |
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Long-term Complications of Diabetes Mellitus |
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58 | (1) |
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Role of Laboratory in Diabetes Mellitus |
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59 | (7) |
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66 | (15) |
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66 | (1) |
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Indications and Limitations of Liver Function Tests |
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67 | (1) |
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Classification of Liver Function Tests |
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68 | (1) |
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Tests that Assess Excretory Function of the Liver |
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68 | (3) |
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Tests Which Assess Synthetic and Metabolic Functions of Liver |
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71 | (2) |
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Tests Which Assess Hepatic Injury (Liver Enzyme Studies) |
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73 | (2) |
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Tests that Assess Clearance if Exogenous Substances from the Liver |
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75 | (1) |
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Interpretation of Liver Function Tests |
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76 | (1) |
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77 | (1) |
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77 | (4) |
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6 Laboratory Tests in Disorders of Lipids |
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81 | (6) |
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81 | (2) |
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Classification of Lipoprotein Disorders |
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83 | (1) |
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Laboratory Tests for Lipoprotein Disorders |
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84 | (3) |
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7 Biochemical Cardiac Markers |
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87 | (6) |
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87 | (2) |
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Biochemical Cardiac Marker Studies |
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89 | (2) |
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Other Cardiac Injury Markers |
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91 | (1) |
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Cardiac Markers with Prognostic Significance |
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91 | (1) |
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Cardiac Marker for Congestive Cardiac Failure |
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92 | (1) |
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8 Examination of Cerebrospinal Fluid |
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93 | (11) |
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Composition of Normal Cerebrospinal Fluid in Adults |
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93 | (1) |
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93 | (1) |
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Functions of Cerebrospinal Fluid |
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93 | (1) |
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Collection of Cerebrospinal Fluid |
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93 | (1) |
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Indications for Lumbar Puncture |
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94 | (1) |
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Complications of Lumbar Puncture |
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95 | (1) |
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Contraindications to Lumbar Puncture |
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95 | (1) |
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Laboratory Examination of Cerebrospinal Fluid |
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95 | (9) |
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9 Examination of Serous Body Fluids and Synovial Fluid |
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104 | (12) |
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104 | (7) |
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111 | (5) |
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116 | (5) |
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116 | (1) |
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116 | (1) |
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Microbiological Examination |
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116 | (1) |
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Examination of Sputum for Mycobacterium tuberculosis |
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117 | (2) |
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Examination for Other Organisms |
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119 | (1) |
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Cytological Examination of Sputum |
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119 | (2) |
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121 | (13) |
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Uses of Laboratory Examination of Feces |
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121 | (1) |
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122 | (9) |
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131 | (3) |
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134 | (5) |
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Normal Gastric Anatomy and Physiology |
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134 | (1) |
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Indications for Gastric Analysis |
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135 | (1) |
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Contraindications to Gastric Analysis |
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136 | (1) |
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Method of Gastric Analysis |
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136 | (2) |
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Other Tests for Gastric Analysis |
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138 | (1) |
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13 Tests for Malabsorption and Pancreatic Function Tests |
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139 | (10) |
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139 | (5) |
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Pancreatic Function Tests |
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144 | (5) |
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14 Thyroid Function Tests |
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149 | (8) |
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Anatomy and Physiology of Thyroid |
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149 | (1) |
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150 | (3) |
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153 | (4) |
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15 Laboratory Tests in Pregnancy |
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157 | (9) |
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157 | (3) |
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First and Second Trimester Screening for Cytogenetic Defects and Neural Tube Defects |
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160 | (2) |
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Assessment of Risk of Preterm Labor |
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162 | (1) |
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Determination of Fetal Lung Maturity |
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162 | (1) |
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163 | (1) |
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Laboratory Evaluation of Diseases During Pregnancy |
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163 | (1) |
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Laboratory Tests in Recurrent Pregnancy Loss |
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164 | (2) |
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166 | (8) |
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166 | (2) |
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168 | (6) |
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174 | (6) |
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Indications for Semen Analysis |
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174 | (1) |
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Collection of Semen for Investigation of Infertility |
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174 | (1) |
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Examination of Seminal Fluid |
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175 | (4) |
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Examination for the Presence of Semen in Medicolegal Cases |
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179 | (1) |
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Examination of Semen to Check the Effectiveness of Vasectomy |
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179 | (1) |
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18 Pyrexia of Unknown Origin |
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180 | (7) |
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180 | (1) |
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Classic Pyrexia of Unknown Origin |
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181 | (3) |
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184 | (1) |
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184 | (1) |
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Human Immunodeficiency Virus-related PUO |
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184 | (3) |
| Section 2: Laboratory Hematology |
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187 | (9) |
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189 | (2) |
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191 | (3) |
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194 | (2) |
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196 | (6) |
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196 | (1) |
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196 | (2) |
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198 | (1) |
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Sequence of Filling of Tubes (Order of Draw of Blood Collection Tubes) |
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199 | (1) |
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Common Sources of Error in Collection of Blood Sample |
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199 | (1) |
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200 | (1) |
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201 | (1) |
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21 Automated Complete Blood Cell Count |
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202 | (11) |
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Principles of Working of Hematology Analyzer |
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203 | (1) |
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204 | (1) |
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Collection of Blood for Complete Blood Count |
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204 | (1) |
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Parameters Measured by Hematology Analyzers |
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204 | (3) |
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207 | (1) |
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207 | (1) |
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Causes of Erroneous Results on Automated CBC |
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208 | (1) |
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Newer Parameters Available on Select Hematology Analyzers |
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208 | (2) |
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Advantages of Hematology Analyzers |
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210 | (1) |
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Limitations of Hematology Analyzers |
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211 | (1) |
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Interpretation of Complete Blood Count |
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211 | (2) |
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22 Estimation of Hemoglobin |
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213 | (4) |
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Indications for Hemoglobin Estimation |
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213 | (1) |
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Methods for Estimation of Hemoglobin |
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213 | (3) |
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216 | (1) |
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217 | (3) |
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Uses of Packed Cell Volume |
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217 | (1) |
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Macromethod (Wintrobe Method) |
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217 | (1) |
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218 | (1) |
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219 | (1) |
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220 | (3) |
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220 | (2) |
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222 | (1) |
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223 | (3) |
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223 | (1) |
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223 | (3) |
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226 | (2) |
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226 | (1) |
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227 | (1) |
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228 | (13) |
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228 | (1) |
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Preparation of Blood Smear (Wedge Method) |
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228 | (1) |
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229 | (1) |
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229 | (1) |
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Examination of Blood Smear |
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230 | (11) |
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241 | (2) |
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241 | (1) |
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241 | (1) |
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242 | (1) |
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29 Erythrocyte Sedimentation Rate |
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243 | (5) |
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Stages of Erythrocyte Sedimentation Rate |
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243 | (1) |
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Factors Affecting Erythrocyte Sedimentation Rate |
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243 | (1) |
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Significance of Erythrocyte Sedimentation Rate |
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243 | (1) |
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Indications for Measurement of Erythrocyte Sedimentation Rate |
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244 | (1) |
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Methods for Estimation of Erythrocyte Sedimentation Rate |
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244 | (2) |
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246 | (2) |
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30 Examination of Bone Marrow |
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248 | (8) |
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248 | (1) |
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Indications for Bone Marrow Examination |
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248 | (1) |
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249 | (1) |
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Sites for Bone Marrow Aspiration or Biopsy |
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249 | (1) |
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250 | (1) |
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Complications of Bone Marrow Aspiration and/or Biopsy |
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251 | (1) |
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Processing of Marrow Specimens |
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251 | (1) |
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Examination of Marrow Specimens |
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252 | (4) |
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31 Hematology of Infectious Diseases |
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256 | (17) |
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256 | (8) |
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264 | (2) |
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266 | (3) |
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269 | (1) |
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Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) |
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269 | (2) |
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Hematological Changes in HIV/AIDS |
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271 | (2) |
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32 Laboratory Tests in Anemia |
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273 | (31) |
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Classification of Anemias |
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273 | (1) |
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Anemias due to Decreased Production of Red Blood Cells |
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273 | (8) |
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Hereditary Disorders of Hemoglobin |
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281 | (4) |
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Disorders of Red Cell Membrane |
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285 | (1) |
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Glucose-6-Phosphate Dehydrogenase Deficiency |
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286 | (1) |
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287 | (4) |
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Paroxysmal Nocturnal Hemoglobinuria |
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291 | (1) |
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Microangiopathic and Macroangiopathic Hemolytic Anemia |
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291 | (1) |
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292 | (1) |
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292 | (1) |
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Approach to Diagnosis of Anemia |
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292 | (12) |
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33 Laboratory Tests in Hematological Malignancies |
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304 | (15) |
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304 | (6) |
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Myelodysplastic Syndromes |
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310 | (1) |
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Myeloproliferative Neoplasms |
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311 | (1) |
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Mature B- and T-Cell Neoplasms |
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312 | (1) |
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313 | (6) |
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34 Laboratory Tests in Bleeding Disorders |
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319 | (21) |
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319 | (3) |
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322 | (6) |
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Approach to the Diagnosis of Bleeding Disorders |
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328 | (12) |
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35 Laboratory Tests in Thrombophilia |
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340 | (8) |
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341 | (2) |
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343 | (1) |
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Association of Thrombophilia with Clinical Presentation |
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344 | (1) |
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345 | (1) |
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Indications for Thrombophilia Testing |
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345 | (1) |
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Diagnosis of Thrombophilia |
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345 | (1) |
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Diagnosis of Deep Venous Thrombosis |
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346 | (1) |
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Diagnosis of Pulmonary Embolism |
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346 | (2) |
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36 Laboratory Tests in Porphyrias |
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348 | (4) |
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Introduction and Classification |
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348 | (1) |
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349 | (1) |
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350 | (2) |
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37 Flow Cytometry and Immunohistochemistry in Hematopathology |
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352 | (11) |
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352 | (5) |
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357 | (6) |
| Section 3: Practical Blood Transfusion |
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363 | (7) |
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363 | (4) |
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367 | (2) |
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Other Blood Group Systems |
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369 | (1) |
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370 | (6) |
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370 | (4) |
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Identical Blood versus Compatible Blood |
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374 | (1) |
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374 | (2) |
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40 Collection of Donor Blood, Processing and Storage |
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376 | (7) |
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376 | (1) |
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Criteria for Selection of Blood Donors |
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377 | (1) |
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Collection of Donor Blood |
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378 | (2) |
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Collection of Blood by Apheresis |
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380 | (1) |
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Processing of Donor Blood |
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381 | (1) |
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381 | (1) |
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382 | (1) |
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382 | (1) |
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41 Screening Tests for Infections Transmissible by Transfusion |
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383 | (4) |
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Organisms Transmissible by Transfusion |
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383 | (1) |
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384 | (2) |
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386 | (1) |
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386 | (1) |
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42 Antibody Screening and Identification |
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387 | (3) |
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387 | (1) |
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388 | (2) |
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390 | (3) |
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Steps in Compatibility Testing |
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390 | (3) |
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44 Whole Blood, Blood Components and Blood Derivatives |
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393 | (5) |
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393 | (1) |
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394 | (2) |
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396 | (1) |
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397 | (1) |
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Recombinant Factor Concentrates |
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397 | (1) |
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45 Adverse Effects of Transfusion |
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398 | (7) |
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Acute Hemolytic Transfusion Reaction |
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398 | (1) |
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Febrile Non-hemolytic Transfusion Reaction |
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399 | (1) |
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Bacterial Contamination of Donor Unit |
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399 | (1) |
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Transfusion-associated Lung Injury |
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399 | (1) |
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Delayed Hemolytic Transfusion Reaction |
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399 | (1) |
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399 | (1) |
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399 | (1) |
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Transfusion-associated Circulatory Overload |
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400 | (1) |
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Iron Overload (Transfusion Hemosiderosis) |
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400 | (1) |
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400 | (1) |
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Transmission of Infections |
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400 | (1) |
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Transfusion-associated Graft-versus-Host Disease |
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401 | (1) |
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Complications Associated with Massive Transfusion |
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401 | (1) |
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Recognition and Investigation of a Transfusion Reaction |
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401 | |
| Appendices |
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Appendix A: Association of Laboratory Test/Finding with Disease(s) or Condition(s) |
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405 | (4) |
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Appendix B: Normal Reference Ranges in Adults |
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409 | (3) |
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Appendix C: Critical Values |
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412 | (1) |
| Index |
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413 | |
