| Section 1: Disorders of Red Cells |
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3 | (6) |
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3 | (1) |
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4 | (5) |
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2 Classification of Anemia |
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9 | (5) |
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9 | (1) |
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10 | (4) |
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14 | (10) |
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14 | (3) |
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17 | (7) |
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24 | (17) |
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Metabolism of vitamin B12 and folic acid |
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25 | (3) |
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Etiology of megaloblastic anemia |
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28 | (1) |
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Laboratory findings of megaloblastic anemia |
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29 | (4) |
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Anemias of vitamin B12 deficiency |
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33 | (5) |
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Anemia of folate deficiency |
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38 | (1) |
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Nonmegaloblastic causes of macrocytic anemias |
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39 | (2) |
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5 Introduction and Classification of Hemolytic Anemia |
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41 | (10) |
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43 | (6) |
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Classification of hemolytic anemias |
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49 | (2) |
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6 Hemolytic Anemias due to Red Cell Membrane Disorders |
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51 | (6) |
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52 | (3) |
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Hereditary elliptocytosis |
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55 | (2) |
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57 | (12) |
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58 | (8) |
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66 | (3) |
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69 | (14) |
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70 | (8) |
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78 | (1) |
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79 | (1) |
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80 | (3) |
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9 Hemolytic Anemias due to Red Cell Enzyme Deficiencies |
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83 | (6) |
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Metabolic pathways in red blood cells |
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83 | (1) |
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Glucose-6-phosphate dehydrogenase deficiency |
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84 | (3) |
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Pyruvate kinase deficiency |
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87 | (2) |
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10 Immunohemolytic Anemia |
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89 | (9) |
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Alloimmune hemolytic anemia |
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89 | (3) |
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Autoimmune hemolytic anemia |
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92 | (6) |
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11 Fragmentation Syndrome |
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98 | (2) |
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98 | (1) |
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99 | (1) |
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12 Paroxysmal Nocturnal Hemoglobinuria |
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100 | (4) |
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100 | (1) |
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Etiology and pathogenesis |
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100 | (1) |
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101 | (1) |
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102 | (2) |
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104 | (6) |
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104 | (1) |
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104 | (1) |
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105 | (1) |
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106 | (1) |
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107 | (3) |
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110 | (2) |
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110 | (1) |
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110 | (1) |
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110 | (1) |
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111 | (1) |
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15 Miscellaneous RBC Disorders |
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112 | (5) |
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Anemia of chronic disease |
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112 | (2) |
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114 | (1) |
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114 | (1) |
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114 | (1) |
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Anemia associated with marrow infiltration (myelophthisic anemia) |
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115 | (2) |
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117 | (4) |
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Hereditary sideroblastic anemias |
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118 | (1) |
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Acquired idiopathic sideroblastic anemia |
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119 | (1) |
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Congenital dyserythropoietic anemias |
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119 | (2) |
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121 | (8) |
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Approach to the diagnosis of anemia |
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121 | (4) |
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Approach to the diagnosis of hemolytic anemia |
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125 | (4) |
| Section 2: Disorders of White Cells |
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18 Quantitative and Qualitative Disorders of White Blood Cells |
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129 | (12) |
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Classification of WBC disorders |
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131 | (1) |
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Quantitative disorders of leukocytes |
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132 | (6) |
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Qualitative disorders of leukocytes |
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138 | (3) |
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19 Infectious Mononucleosis |
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141 | (6) |
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141 | (1) |
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141 | (2) |
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143 | (1) |
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144 | (2) |
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Lesions associated with EBV infection |
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146 | (1) |
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20 Introduction to Acute Leukemia |
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147 | (11) |
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Neoplastic proliferations of white cells |
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147 | (1) |
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148 | (10) |
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21 Acute Lymphoblastic Leukemia |
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158 | (6) |
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Acute lymphoblastic leukemia |
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158 | (4) |
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Acute lymphoblastic lymphoma |
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162 | (2) |
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22 Acute Myelogenous Leukemia and Related Neoplasm |
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164 | (6) |
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Acute myelogenous leukemia |
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164 | (3) |
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167 | (3) |
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23 Myelodysplastic Syndromes |
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170 | (6) |
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170 | (1) |
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170 | (2) |
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Etiology and molecular pathogenesis |
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172 | (1) |
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173 | (1) |
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173 | (3) |
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24 Myeloproliferative Neoplasm |
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176 | (6) |
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Essential thrombocythemia |
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177 | (1) |
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178 | (4) |
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25 Chronic Myelogenous Leukemia and Other Myeloid Neoplasms |
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182 | (10) |
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Chronic myelogenous leukemia |
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182 | (7) |
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Myelodysplastic/Myeloproliferative neoplasms |
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189 | (3) |
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192 | (5) |
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193 | (4) |
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27 Chronic Lymphocytic Leukemia and Other Lymphoid Leukemias |
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197 | (9) |
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Chronic lymphocytic leukemia |
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197 | (4) |
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201 | (1) |
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202 | (4) |
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206 | (13) |
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Multiple myeloma (plasma cell myeloma) |
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207 | (8) |
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215 | (1) |
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Immunoglobulin deposition diseases |
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216 | (1) |
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Monoclonal gammopathy of uncertain significance |
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216 | (1) |
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216 | (3) |
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219 | (7) |
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219 | (2) |
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Development of lymphocytes (lymphopoiesis) |
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221 | (5) |
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226 | (21) |
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Classification of lymphoid neoplasms |
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227 | (1) |
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Precursor lymphoid neoplasms |
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228 | (1) |
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228 | (12) |
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Mature T cell and NK cell neoplasms |
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240 | (7) |
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247 | (17) |
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Classical Hodgkin lymphoma |
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251 | (5) |
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Nodular lymphocyte predominant Hodgkin lymphoma |
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256 | (2) |
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Etiology and pathogenesis of Hodgkin lymphoma |
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258 | (1) |
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259 | (1) |
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260 | (4) |
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32 Langerhans Cell Histiocytosis |
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264 | (5) |
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264 | (1) |
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264 | (1) |
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265 | (4) |
| Section 3: Disorders of Hemostasis |
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33 Normal Hemostasis and its Components |
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269 | (11) |
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269 | (1) |
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270 | (1) |
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271 | (3) |
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Coagulation regulatory mechanism |
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274 | (1) |
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275 | (1) |
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276 | (4) |
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34 Bleeding Disorders: Vessel Wall Abnormalities |
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280 | (6) |
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280 | (3) |
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Bleeding disorders caused by vessel wall abnormalities |
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283 | (3) |
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35 Bleeding Disorders: Abnormalities of Platelet |
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286 | (14) |
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Quantitative platelet disorders |
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286 | (10) |
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Qualitative platelet disorders |
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296 | (4) |
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36 Bleeding Disorders: Abnormalities of Coagulation Factors |
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300 | (13) |
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301 | (5) |
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Acquired coagulation disorders |
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306 | (1) |
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Disseminated intravascular coagulation |
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307 | (6) |
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37 Thrombotic Disorders: Hypercoagulable States |
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313 | (8) |
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Inherited hypercoagulable states |
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314 | (1) |
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Acquired hypercoagulable states |
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315 | (6) |
| Section 4: Clinical Pathology |
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38 Anticoagulants and Collection of Blood |
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321 | (8) |
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321 | (2) |
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Steps in hematological investigation |
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323 | (6) |
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329 | (6) |
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329 | (2) |
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331 | (2) |
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333 | (2) |
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335 | (8) |
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Indications for hemoglobin estimation |
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335 | (1) |
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Methods of hemoglobin estimation |
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335 | (8) |
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343 | (11) |
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345 | (2) |
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347 | (2) |
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349 | (2) |
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Absolute eosinophil count |
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351 | (3) |
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42 Peripheral Blood Smear Examination |
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354 | (12) |
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354 | (1) |
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Preparation of the peripheral blood smear |
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355 | (1) |
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356 | (1) |
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356 | (1) |
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Examination of a peripheral blood smear |
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357 | (9) |
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366 | (4) |
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Methods of reticulocyte count |
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366 | (2) |
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Significance of reticulocyte count |
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368 | (2) |
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44 Hematocrit, Red Cell Indices and ESR Estimation |
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370 | (11) |
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370 | (3) |
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Red cell (erythrocyte) indices |
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373 | (2) |
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Erythrocyte sedimentation rate |
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375 | (3) |
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Lupus erythematosus cell test |
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378 | (3) |
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45 Bone Marrow Examination |
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381 | (6) |
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381 | (3) |
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Bone marrow trephine biopsy |
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384 | (3) |
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46 Osmotic Fragility Test |
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387 | (3) |
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387 | (1) |
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388 | (2) |
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47 Cytochemistry in Leukemia |
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390 | (4) |
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390 | (1) |
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390 | (1) |
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391 | (1) |
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391 | (1) |
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Periodic acid-Schiff reaction |
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391 | (1) |
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Neutrophil alkaline phosphatase |
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392 | (2) |
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48 Laboratory Evaluation of Hemostatic and Thrombotic Disorders |
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394 | (14) |
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Tests for platelet component |
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395 | (1) |
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Tests for platelet and vascular component |
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396 | (2) |
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Tests for coagulation component |
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398 | (4) |
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Tests for fibrinolytic activity |
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402 | (6) |
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49 Automation in Hematology |
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408 | (10) |
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Automated hematology analyzer |
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408 | (7) |
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415 | (3) |
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418 | (28) |
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Collection of urine specimen |
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418 | (1) |
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419 | (1) |
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419 | (1) |
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419 | (5) |
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424 | (15) |
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439 | (7) |
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446 | (5) |
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Examination of body fluids |
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447 | (1) |
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Examination of synovial fluids |
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448 | (3) |
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52 Cerebrospinal Fluid Examination |
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451 | (6) |
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Importance of CSF examination |
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451 | (1) |
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451 | (2) |
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453 | (4) |
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457 | (9) |
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Different procedures of semen analysis |
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457 | (5) |
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Cryopreservation of spermatozoa |
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462 | (4) |
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466 | (4) |
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466 | (4) |
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470 | (4) |
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470 | (1) |
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471 | (3) |
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474 | (10) |
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Cytology of female genital tract |
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477 | (3) |
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Cytology of other systems |
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480 | (1) |
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Buccal smear for Barr body |
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480 | (1) |
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FNAC appearance of some common lesions |
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481 | (3) |
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57 Glucose Tolerance Test |
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484 | (3) |
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Oral glucose tolerance test |
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484 | (2) |
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486 | (1) |
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487 | (8) |
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487 | (5) |
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492 | (1) |
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Other blood group systems |
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493 | (2) |
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495 | (4) |
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495 | (2) |
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Indirect antiglobulin test |
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497 | (2) |
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499 | (11) |
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499 | (4) |
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503 | (2) |
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505 | (3) |
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508 | (2) |
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61 Hematopoietic Stem Cell Transplantation |
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510 | (5) |
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510 | (1) |
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Sources of hematopoietic stem cells |
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510 | (1) |
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Types of hematopoietic stem cell transplant |
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511 | (1) |
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Indications for hematoporetic stem cell transplantation |
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511 | (1) |
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Autologous stem cell transplant |
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511 | (1) |
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Allogeneic stem cell transplantation |
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512 | (1) |
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Complications of hematopoietic stem cell transplantation |
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513 | (2) |
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62 Gastric Function Tests |
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515 | (3) |
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Tests for gastric acid secretion |
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515 | (1) |
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516 | (2) |
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63 Liver Function Tests and Liver Biopsy |
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518 | (11) |
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518 | (6) |
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524 | (5) |
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529 | (4) |
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529 | (2) |
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531 | (2) |
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65 Thyroid Function Tests |
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533 | (5) |
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534 | (4) |
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538 | (8) |
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539 | (6) |
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Stool culture and sensitivity |
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545 | (1) |
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546 | (11) |
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Symptoms and signs that suggest a blood disease |
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546 | (1) |
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Patterns strongly suggestive of a blood disease |
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547 | (8) |
| Bibliography |
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555 | (2) |
| Appendices |
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557 | (12) |
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Appendix 1 WHO classification of tumors of hematopoietic and lymphoid tissues |
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557 | (5) |
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Appendix 2 Laboratory values of clinical importance |
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562 | (7) |
| Index |
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569 | |
