Acronyms And Abbreviations |
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xxv | |
Abstract |
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1 | (4) |
Summary |
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5 | (18) |
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1 Advancing Public Health Emergency Preparedness And Response System Capabilities To Respond To Increasing Threats |
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23 | (1) |
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24 | (1) |
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Conceptualizing the Complex PHEPR System |
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25 | (7) |
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The Building Blocks of the PHEPR System |
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25 | (5) |
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Defining a PHEPR Practice |
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30 | (2) |
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Underlying Reasons for the Current State of the PHEPR Evidence Base |
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32 | (7) |
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A Rapidly Evolving PHEPR System |
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33 | (3) |
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The Increasing Complexity of Public Health Emergencies and the PHEPR System |
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36 | (1) |
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Methodological Challenges for PHEPR Research |
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37 | (1) |
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A Poorly Organized Approach to PHEPR Research and Implications for the PHEPR Researcher Pipeline |
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38 | (1) |
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A Well-Documented Gap Between PHEPR Research and Practice |
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38 | (1) |
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The Importance of Evidence-Based Practice and Guidelines |
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39 | (2) |
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The Emergence of Evidence-Based Guidelines and Policies to Promote Evidence-Based Practice |
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40 | (1) |
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Moving Beyond the Traditional Evidence Hierarchy for Evaluating the Effectiveness of PHEPR Practices |
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40 | (1) |
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41 | (5) |
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41 | (1) |
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Report Audiences and Uses |
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42 | (2) |
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Organization of the Report |
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44 | (2) |
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46 | (3) |
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2 The Landscape And Evolution Of Public Health Emergency Preparedness And Response Research In The United States |
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49 | (1) |
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Characterizing the Research on PHEPR: A Map of the Evidence |
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49 | (1) |
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Overall Distribution of Articles Within the 15 PHEPR Capabilities |
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50 | (2) |
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Quantitative Impact Studies Within the 15 PHEPR Capabilities |
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52 | (2) |
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Studies Within Specific Practice Areas of the 15 PHEPR Capabilities |
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54 | (1) |
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Implications for Future Research and Evidence Reviews |
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55 | (2) |
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A Look Back at PHEPR Research Programs |
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57 | (5) |
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Centers for Disease Control and Prevention-Funded Academic PHEPR Workforce Development and Research Centers |
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57 | (2) |
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Other Federal Disaster Research Programs |
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59 | (1) |
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Specific Efforts to Enhance the Conduct of Research During Public Health Emergencies |
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60 | (2) |
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Limitations of PHEPR Research Programs |
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62 | (3) |
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Misaligned and Unclear Research Priorities |
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62 | (1) |
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Lack of Infrastructure to Support the Conduct of Quality PHEPR Research |
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63 | (1) |
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Lack of Coordination Across Funders and Shortcomings of Research Funding |
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64 | (1) |
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65 | (1) |
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66 | (5) |
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3 An Evidence Review And Evaluation Process To Inform Public Health Emergency Preparedness And Response Decision Making |
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71 | (1) |
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Evolving Philosophies for Evaluating Evidence to Inform Evidence-Based Practice: Implications for PHEPR |
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72 | (1) |
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Limitations of the Traditional Evidence Hierarchy |
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72 | (1) |
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Evolving Methods for Evaluating Complex Health Interventions in Complex Systems |
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73 | (2) |
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Implications for Evaluating Evidence in the PHEPR System |
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75 | (2) |
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How Do Different Fields Evaluate Evidence?: A Review of Existing Frameworks |
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77 | (4) |
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Applying a Methodology to Review, Synthesize, and Assess the COE for PHEPR Practices |
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81 | (20) |
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Formulating the Scope of the Reviews and Searching the Literature |
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83 | (3) |
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Synthesizing and Assessing the COE |
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86 | (9) |
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Formulating the Practice Recommendations and Implementation Guidance |
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95 | (6) |
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Limitations, Lessons Learned, and Recommendations for the Future |
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101 | (9) |
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Limitations of the Committee's Evidence Review and Evaluation Methodology |
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102 | (1) |
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Reflections and Lessons Learned from the Mixed-Method Reviews |
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103 | (2) |
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Need for Ongoing PHEPR Evidence Reviews |
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105 | (2) |
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An Infrastructure to Sustain PHEPR Evidence Reviews |
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107 | (3) |
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110 | (6) |
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4 Engaging With And Training Community-Based Partners To Improve The Outcomes Of At-Risk Populations |
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116 | (2) |
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Description of the Practice |
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118 | (1) |
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118 | (1) |
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Scope of the Problem Addressed by the Practice |
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118 | (3) |
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Overview of the Key Review Questions and Analytic Framework |
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121 | (3) |
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Defining the Key Review Questions |
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121 | (1) |
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122 | (2) |
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Overview of the Evidence Supporting the Practice Recommendation |
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124 | (6) |
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124 | (3) |
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Balance of Benefits and Harms |
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127 | (1) |
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Acceptability and Preferences |
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128 | (1) |
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Feasibility and PHEPR System Considerations |
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128 | (1) |
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Resource and Economic Considerations |
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128 | (1) |
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129 | (1) |
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129 | (1) |
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Considerations for Implementation |
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130 | (1) |
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Facilitators for CBP Engagement |
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130 | (1) |
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Facilitators for CBP Training |
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131 | (1) |
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Practice Recommendation, Justification, and Implementation Guidance |
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131 | (2) |
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Evidence Gaps and Future Research Priorities |
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133 | (2) |
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135 | (3) |
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5 Activating A Public Health Emergency Operations Center |
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138 | (2) |
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Description of the Practice |
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140 | (1) |
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140 | (1) |
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Scope of the Problem Addressed by the Practice |
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141 | (3) |
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Overview of the Key Review Questions and Analytic Framework |
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144 | (3) |
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Defining the Key Review Questions |
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144 | (1) |
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145 | (2) |
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Overview of the Evidence Supporting the Practice Recommendation |
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147 | (3) |
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147 | (1) |
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Balance of Benefits and Harms |
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147 | (1) |
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Acceptability and Preferences |
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148 | (1) |
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Feasibility and PHEPR System Considerations |
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149 | (1) |
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Resource and Economic Considerations |
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149 | (1) |
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149 | (1) |
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150 | (1) |
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Considerations for Implementation |
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150 | (4) |
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Factors in Determining When to Activate a PHEOC |
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150 | (2) |
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Other Implementation Considerations |
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152 | (2) |
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Practice Recommendation, Justification, and Implementation Guidance |
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154 | (2) |
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Evidence Gaps and Future Research Priorities |
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156 | (2) |
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158 | (2) |
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6 Communicating Public Health Alerts And Guidance With Technical Audiences During A Public Health Emergency |
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160 | (2) |
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Description of the Practice |
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162 | (1) |
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162 | (2) |
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Scope of the Problem Addressed by the Practice |
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164 | (1) |
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Overview of the Key Review Questions and Analytic Framework |
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165 | (2) |
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Defining the Key Review Questions |
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165 | (1) |
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165 | (2) |
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Overview of the Evidence Supporting the Practice Recommendation |
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167 | (4) |
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167 | (2) |
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Balance of Benefits and Harms |
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169 | (1) |
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Acceptability and Preferences |
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169 | (1) |
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Feasibility and PHEPR System Considerations |
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170 | (1) |
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Resource and Economic Considerations |
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170 | (1) |
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170 | (1) |
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170 | (1) |
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Considerations for Implementation |
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171 | (3) |
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Engaging Technical Audiences in the Development of Communication Plans, Protocols, and Channels |
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171 | (1) |
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Considerations for Selection of Communication Channels |
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172 | (1) |
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Facilitating Communication with Technical Audiences During a Public Health Emergency |
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173 | (1) |
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Practice Recommendation, Justification, and Implementation Guidance |
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174 | (1) |
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Evidence Gaps and Future Research Priorities |
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175 | (2) |
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177 | (3) |
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7 Implementing Quarantine To Reduce Or Stop The Spread Of A Contagious Disease |
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180 | (1) |
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Description of the Practice |
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182 | (2) |
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182 | (1) |
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Scope of the Problem Addressed by the Practice |
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183 | (2) |
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Overview of the Key Review Questions and Analytic Framework |
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185 | (3) |
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Defining the Key Review Questions |
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185 | (1) |
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186 | (2) |
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Overview of the Evidence Supporting the Practice Recommendation |
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188 | (6) |
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188 | (2) |
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Findings from a Synthesis of Modeling Studies: Quarantine Is More Effective Under Certain Circumstances |
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190 | (1) |
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Balance of Benefits and Harms |
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191 | (1) |
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Acceptability and Preferences |
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192 | (1) |
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Feasibility and PHEPR System Considerations |
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192 | (1) |
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Resource and Economic Considerations |
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192 | (1) |
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193 | (1) |
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193 | (1) |
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Considerations for Implementation |
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194 | (4) |
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Facilitating Adherence to and Minimizing Harms from Quarantine Measures |
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194 | (2) |
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Other Implementation Considerations |
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196 | (2) |
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Practice Recommendation, Justification, and Implementation Guidance |
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198 | (1) |
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Evidence Caps and Future Research Priorities |
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199 | (3) |
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Quarantine and the COVID-19 Pandemic |
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201 | (1) |
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202 | (3) |
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8 Improving And Expanding The Evidence Base For Public Health Emergency Preparedness And Response |
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205 | (1) |
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A National PHEPR Science Framework |
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206 | (1) |
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Key Components of a National PHEPR Science Framework |
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207 | (5) |
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Ensuring Adequate Infrastructure and Supporting Mechanisms to Facilitate the Conduct of PHEPR Research |
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212 | (4) |
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Conclusion and Recommendations |
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216 | (2) |
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Supporting Methodological Improvements for PHEPR Research |
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218 | (6) |
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Common Evidence Guidelines |
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218 | (3) |
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Standards for Reporting of Study Information |
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221 | (2) |
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Conclusion and Recommendation |
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223 | (1) |
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Improving Systems to Generate High-Quality Experiential Evidence for PHEPR |
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224 | (8) |
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Limitations of AARs as a Source of Experiential Evidence for Mixed-Method Evidence Reviews |
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225 | (2) |
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Strengthening Methodological Approaches |
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227 | (2) |
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Establishing Mechanisms for Analysis and Dissemination of Lessons Learned from AARs |
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229 | (2) |
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Fostering a Culture of Quality Improvement |
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231 | (1) |
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Conclusions and Recommendation |
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231 | (1) |
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Workforce Capacity Development for Researchers and Practitioners in PHEPR |
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232 | (3) |
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232 | (1) |
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233 | (1) |
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Conclusion and Recommendation |
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234 | (1) |
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Translation, Dissemination, and Implementation of PHEPR Research to Practice |
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235 | (5) |
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Building Implementation Capacity |
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235 | (3) |
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Conclusion and Recommendation |
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238 | (2) |
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Annex 8-1 Genres of Research to Inform Public Health Emergency Preparedness and Response Practices |
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240 | (4) |
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244 | (7) |
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A Detailed Description Of The Committee's Methods For Formulating The Scope Of The Reviews And Capturing The Evidence |
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251 | (40) |
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B Mixed-Method Reviews Of Selected Topics |
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291 | (142) |
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B-1 Mixed-Method Review Of Strategies For Engaging With And Training Community-Based Partners To Improve The Outcomes Of At-Risk Populations |
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293 | (40) |
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B-2 Mixed-Method Review Of Activating A Public Health Emergency Operations Center |
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333 | (24) |
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B-3 Mixed-Method Review Of Channels For Communicating Public Health Alerts And Guidance With Technical Audiences During A Public Health Emergency |
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357 | (30) |
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B-4 Mixed-Method Review Of Implementing Quarantine To Reduce Or Stop The Spread Of A Contagious Disease |
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387 | (46) |
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C Commissioned Reports That Informed The Four Mixed-Method Reviews |
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433 | (2) |
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D Commissioned Scoping Review And Series Of Evidence Maps |
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435 | (24) |
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E Public Committee Meeting Agendas And Proceedings Of A Workshop--In Brief |
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459 | (6) |
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F Committee Member Biosketches |
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465 | |