I Regulation of Stem Cell Proliferation.- 1 Regulation of Stem Cell
Proliferation.- Experimental Evidence.- Summary.- References.- 2 Surface
Antigens of Hemopoietic Stem Cells: The Expression of BAS, Thy-1, and H-2
Antigens on CFU-s.- Materials and Methods.- Results.- Discussion.- Summary.-
Acknowledgments.- References.- 3 The Regulation of Hemopoiesis: Effect of
Thymosin or Thymocytes in a Diffusion Chamber.- Materials and Methods.-
Results.- Discussion.- Summary.- Acknowledgments.- References.- 4 Anti-CFU-s
Activity of Rabbit Anti-mouse Brain Serum: Mechanism of Action.- Materials
and Methods.- Results.- Discussion.- Summary.- Acknowledgments.- References.-
II Physiology of Committed Stem Cells.- 5 The Control of Neutrophil and
Macrophage Production at the Progenitor Cell Level.- Granulocyte-macrophage
Colony-forming Cells.- Control by GM-colony-stimulating Factor (GM-CSF).-
Nature and Sources of GM-CSF.- Role of Macrophages and Lymphocytes.- GM-CSF
and Myeloid Leukemia.- General Comment.- Summary.- Acknowledgment.-
References.- 6 The Mononuclear Phagocyte and Its Regulatory Interactions in
Hemopoiesis.- Dualism between CSF and Synthetic Prostaglandins.- Cyclic
3?,5-Adenosine Monophosphate in the Mediation of PGE Activity.- Regulation of
Granulopoiesis and Macrophage Production by Macrophage-derived PGE.- The
Regulatory Role of Macrophages in Lymphopoiesis.- The Macrophage and Other
Hemopoietic Cells.- Summary.- References.- 7 Analysis of the Cells Forming
Pure and Mixed Erythroid Colonies in Agar after Stimulation by Pokeweed
Mitogen-stimulated, Spleen-conditioned Medium.- Materials and Methods.-
Results.- Discussion.- Summary.- Acknowledgment.- References.- 8 Current
Studies on the Proliferation of Cells of the Mononuclear Phagocyte System.-
Origin and Kinetics of Mononuclear Phagocytes.- Regulation of Monocyte
Production.- In Vitro Proliferations of Bone Marrow Mononuclear Phagocytes.-
Summary.- Acknowledgment.- References.- 9 Colony-forming Cells in the Thymus
and Mesenteric Lymph Nodes of Mice Engrafted with Lewis Lung Carcinoma
Cells.- Materials and Methods.- Results.- Discussion.- Summary.-
Acknowledgment.- References.- III Transplantation Immunology.- 10 Expression
of Normal and Leukemia associated Antigens on Blood Cell Malignancies.-
Materials and Methods.- Results and Conclusions.- Summary.- Acknowledgment.-
References.- 11 Leukocyte Transfusions for the Modification of
Host-versus-graft Reactions in Dogs.- Materials and Methods.- Results.-
Discussion.- Summary.- Acknowledgment.- References.- 12 Minor
Histocompatibility Systems in Dogs.- Materials and Methods.- Results.-
Discussion.- Acknowledgments.- Summary.- References.- 13 The Role of
Mononuclear Phagocytes in the Defense against Infections and Malignancies.-
Macrophages and the Immune Response.- Effects of the Humoral Immune Response
on Macrophage Functions.- Effects of the Cell-mediated Immune Response on
Macrophage Functions.- Microbiocidal Mechanisms of Macrophages.- Role of
Macrophages in the Defense against Neoplastic Disease.- Summary.-
Acknowledgment.- References.- 14 Enhancement of Immunological Responses by
Methotrexate Pretreatment as a Result of an Eventual Elimination of
Suppressor Cells.- Materials and Methods.- Results.- Discussion.- Summary.-
Acknowledgment.- References.- 15 Syngeneic and Autologous Bone Marrow
Transplantation after Noncurative Chemotherapy with AAFC, DMM, and
Cyclophosphamide in Tumor-bearing Mice.- Materials and Methods.- Preparation
of Cel Inocula.- Treatment of Bone Marrow Cells with Anti-Thy 1.2 Serum plus
Complement.- Immunization Procedures.- X-irradation.- Statistical Analysis.-
Experimental Design.- Results.- Discussion.- Summary.- Acknowledgements.-
References.- IV Therapeutic Approaches to Aplastic Anemia.- 16 On the
Pathogenesis and Treatment of Aplastic Anemia.- Materials and Methods.-
Results.- Discussion.- Summary.- Acknowledgements.- References.- 17
Engraftment of HLA Identical Marrow in Treatment of Severe Aplastic Anemia:
Results of 110 Consecutive Transplants.- Materials and Methods.- Results.-
Discussion.- Summary.- Acknowledgement.- References.- 18 The Role of
Cyclophosphamide and Total-body Irradiation in Marrow Transplantation for
Severe Aplastic Anemia.- Materials and Methods.- Results.- Discussion.-
Summary.- Acknowledgements.- References.- 19 Histocompatibility Testing for
Bone- George W. Santos and Saul J. Sharkis marrow Grafting.- The Selection of
an HLA-compatible Donor.- Detection of Prior Sensitization.- Summary.-
Acknowledgments.- References.- 20 Recent Developments in Histocompatibility
Testing in Bone Marrow Transplantation.- What Progress Has Been Made in
Recognizing Non-HLA Antigens?.- Platelet Antigens.- H-Y Immunity.- Can
HLA-Identical Unrelated Donors Be Used in Bone Marrow Transplantation?.- The
Influence of Sensitization on the Effectiveness of Immunosuppression.-
Summary.- Acknowledgment.- References.- Summary.- 21 Transplantation of
Lymphoid Cells in Patients with Severe Combined Immunodeficiency (SCID).-
Characteristics of Patients with SCID.- Grafting of Fetal Tissue.- Grafting
of Bone Marrow Tissue.- Immunological Dysregulation Associated with Mild
GvHD.- Defects of Precursor T-cells in SCID with B-lymphocytes.- Conclusion.-
Summary.- Acknowledgment.- References.- V Treatment of Leukemia.- 22
Experience with Syngeneic Marrow Transplantation in Brown-Norway and
Wistar-Furth Rat Models of Acute Myelogenous Leukemia.- Materials and
Methods.- Results.- Discussion.- Summary.- Acknowledgment.- References.- 23
Marrow Transplantation for Acute Leukemia.- Summary.- Acknowledgment.-
References.- 24 Use of Decontamination and a Protected Environment to Prevent
Secondary Disease following Adoptive Immunotherapy of Acute Leukemia in
Mice.- Materials and Methods.- Results.- Conclusions.- Summary.-
Acknowledgments.- References.- 25 Procurement of Proliferative and Quiescent
Acute Leukemia Cells by Centrifugal Elutriation.- Methods.- Results.-
Discussion.- Summary.- Acknowledgment.- References.- VI Advances in
Experimental Hematology.- 26 Cellular Requirements for Induction of
Colony-stimulating Factor in Lymphoid Cell Cultures Stimulated by T- and
B-Cell Mitogens.- Materials and Methods.- Results.- Discussion.- Summary.-
Acknowledgments.- References.- 27 Serum Blocking Factor-mediated Decrease of
T-Cell Immunity Induced by Soluble Histocompatibility Antigens (SHA); Similar
Effects of Antibody-free SHA-raised and Hemagglutinating enhancing Sera.-
Materials and Methods.- Results.- Humoral Immunity of Mice Treated with SHA.-
Discussion.- Summary.- Acknowledgment.- References.- 28 Ultrastructural
Analysis of Preserved Dog Granulocytes.- Materials and Methods.- Results.-
Discussion.- Summary.- Acknowledgment.- References.- 29 Relationship between
Colony-forming Cells in Diffusion Chambers in Vivo (CFU-d) and Colony-forming
Cells in Agar in Vitro (CFU-c): 22j Physical Separation and Kinetics in
Culture.- Materials and Methods.- Results.- Discussion.- Summary.-
Acknowledgments.- References.
