Lymphomas classically manifest themselves in the lymph nodes but can also present in other bodily tissues or systems; the organ where exactly they present may make a very great difference to the strategy that should be adopted for their management. This topic has only recently been consistently addressed as an issue on its own, apart from the rest of the lymphomas, and this text is the first to apply modern systems of classification, diagnosis and management. This text is essential reading for hematologic oncologists and hematopathologists.
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| Preface |
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xi | |
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Challenging issues in the management of extranodal lymphomas |
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3 | (7) |
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Historical prospect for the concept of primary extranodal lymphoma |
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10 | (4) |
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Epidemiology of extranodal lymphomas |
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14 | (10) |
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Infectious etiopathogenesis of extranodal lymphomas |
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24 | (10) |
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Lymphocyte homing and immunology of extranodal lymphoid tissues |
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34 | (16) |
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Specific management problems posed by the primary extranodal presentations. Part I - staging and response evaluation |
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50 | (8) |
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Specific management problems posed by the primary extranodal presentations. Part II - local control of localized disease |
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58 | (9) |
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PART II: PATHOBIOLOGY AND CLINICOPATHOLOGICAL CORRELATIONS |
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Pathobiology and molecular basis of MALT lymphoma |
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67 | (11) |
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Principle of the WHO classification with special reference to aggressive extranodal lymphomas |
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78 | (36) |
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MALT lymphoma pathology, initial diagnosis, and post-treatment evaluation |
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114 | (13) |
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PART III: MAIN ENTITIES/LOCATIONS |
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Primary central nervous system lymphoma |
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127 | (12) |
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Primary testicular lymphoma |
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139 | (8) |
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Intravascular large B-cell lymphoma |
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147 | (8) |
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Nasal natural killer/T-cell lymphoma |
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155 | (13) |
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168 | (6) |
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174 | (9) |
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183 | (13) |
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Primary mediastinal (thymic) large B-cell lymphoma |
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196 | (16) |
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MALT-Type lymphoma of the orgit and ocular adnexae |
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212 | (12) |
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Primary splenic marginal zone lymphomas and other non-MALT marginal zoze lymphomas |
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224 | (9) |
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Gastrointestinal tract lymphomas |
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233 | (11) |
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244 | (21) |
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Primary estranodal head and neck lymphomas |
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265 | (12) |
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277 | (12) |
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Extranodal lymphomas in patients with HIV infection |
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289 | (10) |
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Primary effusion lymphoma |
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299 | (8) |
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Rare primary extranodal sites (genitourinary, adrenal, cardiac, meningeal, esophageal, pancreatic, gall bladder, and soft tissue lymphomas) |
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307 | (13) |
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Extranodal involvement Hodgkin's lymphoma |
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320 | (6) |
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| Index |
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326 | |
About the editors Franco Cavalli is Director of the Institute of Oncology of Southern Switzerland Bellinzona, Switzerland Harald St ein is Director of the Institut für Pathologie, Charité-Campus Benjamin Franklin, Berlin, Germany Em anuele Zucca is Head of the Lymphoma Unit at the Institute of Oncology of Southern Switzerland, Bellinzona, Switzerland
