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Preface I. SARS-CoV-2 and COVID-19: Introductory chapters and setting the scene
1. Coronavirus Disease 2019 (COVID-19) pandemic in context: Systemic effects
2. Early warning signals of SARS-CoV-2 infection
3. Mobile phones and their use to study dynamics of COVID19 pandemic II. Structure, transmission and avoidance
4. Cis regulatory elements: A novel communication route between the host cell and SARS-CoV-2 genome
5. SARS-CoV-2 ORF8: Structure, Evolution, Molecular Function, and Its Contribution to the Pathogenicity of the Virus
6. SARS-CoV-2 Spike Protein Binding Ligands and Its Application in COVID-19 Therapeutics.
7. Autophagy and COVID-19
8. The Omicron variant of SARS-CoV-2
9. Monitoring SARS-CoV-2 spread in hospitals
10. Computational analysis of mutations in SARS-CoV-2 variants spike protein and protein interactions
11. Airborne transmission of SARS-CoV-2
12. Reducing transmission of SARS-CoV-2 with face masks: its potential protective effects
13. Digital twin of ventilation system against COVID-19 transmission and infection risk
14. SARS-CoV-2 infection and transmission in pets
15. SARS-CoV-2 transmission in dental practices
16. SARS-CoV-2 compared with influenza and respiratory syncytial virus in terms of vertical transmission
17. Reducing droplets and aerosols in the surgical setting and applications to the COVID-19 pandemic
18. SARS-CoV motion dynamics: linking in droplet size
19. Ventilation and airborne particles in classrooms: implications for the COVID-19 pandemic
20. Environmental SARS-CoV-2 transmission and e-cigarette aerosols III. Impact and Effects
21. The Impact of COVID-19 on First Responders
22. COVID-19 and suspected drug-induced liver injury
23. Pulmonary fibrosis in COVID-19
24. The effect of SARS-CoV-2 infection on cancer: clinical correlation and potential pathological mechanism
25. Severe SARS-CoV-2, platelet-endothelium interactions and cardiovascular damage
26. Cardio-metabolic Syndrome and COVID-19: Pathophysiological aspects
27. COVID-19 and Type I and II diabetes: an overview
28. COVID-19 and older adults: an overview
29. COVID-19 and male fertility: an overview
30. COVID-19 and obesity: an overview IV. Treatments, strategies and vaccines
31. COVID-19 vaccines and their impact: an overview
32. Exploring the Promise of COVID-19 Vaccines: A Review of Preclinical Studies
33. Drugs actively being investigated for use in COVID-19
34. The biology of neutralizing antibody cocktail therapy with REGN-COV
35. The intensive care unit and percutaneous tracheostomy in COVID-19
36. Cardiac effects of drugs and vaccines used to treat or prevent COVID -19
37. COVID-19 Pandemic and isolation: impact on sleep
38. Strategies in the COVID-19 pandemic: Disinfection of gloved hands
39. In silico studies on established antivirals on SARS-CoV-2 RNA-dependent RNA polymerase
40. The COVID-19 cytokine storm and its immunomodulatory treatment
41. Safety and efficacy of nebulization for reducing the intensity of viral load and clinical manifestations in patients with COVID-19 V. Detection and biomarkers
42. Bronchoalveolar lavage (BAL) and use in detection of SARS-CoV-2
43. SARS-CoV-2 testing and vaccination among people who use drugs
44. Homocysteine as a biomarker in COVID-19
45. Assessment of smell and taste in COVID-19
46. S-gene analysis: RT-PCR and Sanger sequencing applied to SARS-CoV-2 virus
47. False-negatives in screening for SARS-CoV-2
48. Sample pooling and SARS-CoV-2 assays
49. Biomarkers of Invasive Mechanical Ventilation in Obesity and Metabolic Syndrome VI. Case studies with mini review
50. Hypoxia and heart-lung interactions in COVID-19: The significance of right heart dysfunction and shunt
51. CASE STUDY: Neurology, ulnar nerve dysfunction and COVID-19
52. CASE STUDY: Acute kidney injury and COVID-19
53. CASE STUDY: The detection and treatment of a pneumothorax in a patient with Coronavirus Disease 2019 pneumonia
54. CASE STUDY: Conducting ventilation and airflow studies where airborne outbreaks of SARS-CoV-2 have possibly occurred: preventing recurrence VII. Resources
55. Recommended Resources for the Features, Transmission and Detection of Coronavirus Disease 2019 (COVID-19)