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ix | |
Foreword |
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xiii | |
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Preface |
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xv | |
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Section 1 General principles |
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1 The rationale for fetal therapy |
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1 | (11) |
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2 Insights into pathogenesis of adult cardiovascular disease from fetal animal studies |
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12 | (12) |
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3 Human embryology: molecular mechanisms of embryonic disease |
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24 | (15) |
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4 Ethics of fetal therapy |
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39 | (6) |
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5 Fetal therapy choices: about risks, emotions, and the doctor's role in the decision-making process |
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45 | (10) |
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Danielle R. M. Timmermans |
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Section 2 Fetal disease: pathogenesis and principles |
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6 Red cell alloimmunization |
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55 | (12) |
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7 Fetal and neonatal alloimmune thrombocytopenia |
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67 | (11) |
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8.1 Fetal dysrhythmias: the effects of antiarrhythmic therapy on the immature heart |
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78 | (9) |
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8.2 Fetal dysrhythmias: clinical management |
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87 | (13) |
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9.1 Structural heart disease: embryology |
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100 | (13) |
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Adriana C. Gittenberger-de Groot |
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9.2 Structural heart disease: genetic influences |
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113 | (10) |
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9.3 Structural heart disease: fetal cardiac interventions |
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123 | (5) |
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10.1 Manipulation of amniotic fluid volume: homeostasis of fluid volumes in the amniotic cavity |
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128 | (9) |
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10.2 Manipulation of amniotic fluid volume: oligohydramnios and polyhydramnios |
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137 | (8) |
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11.1 Twin-to-twin transfusion syndrome: scientific basis |
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145 | (11) |
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11.2 Twin-to-twin transfusion syndrome: placental circulation |
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156 | (10) |
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11.3 Twin-to-twin transfusion syndrome: cardiovascular manifestations |
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166 | (7) |
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11.4 Twin-to-twin transfusion syndrome: treatment by fetoscopic laser ablation |
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173 | (11) |
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11.5 Twin-to-twin transfusion syndrome: management of stage I disease |
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184 | (3) |
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12.1 Twin reversed arterial perfusion (TRAP) sequence: pathophysiology |
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187 | (6) |
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12.2 Twin reversed arterial perfusion (TRAP) sequence: in-utero treatment |
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193 | (7) |
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13.1 Fetal infections: immune responses to congenital infections |
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200 | (8) |
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13.2 Fetal infections: clinical management |
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208 | (30) |
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14.1 Fetal urinary tract obstruction: pathophysiology |
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238 | (8) |
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14.2 Fetal urinary tract obstruction: prenatal assessment and prognosis |
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246 | (7) |
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14.3 Fetal urinary tract obstruction: fetal cystoscopy |
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253 | (8) |
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14.4 Fetal urinary tract obstruction: in-utero intervention |
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261 | (10) |
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15.1 Fetal lung growth, development, and lung fluid: physiology and pathophysiology |
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271 | (11) |
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15.2 Fetal lung growth, development, and lung fluid: clinical management of pleural effusion and pulmonary pathology |
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282 | (19) |
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16.1 Neural tube defects: pathophysiology and prevention |
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301 | (10) |
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16.2 Neural tube defects: clinical management |
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311 | (9) |
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17.1 Fetal tumors: pathophysiology |
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320 | (9) |
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17.2 Fetal tumors: clinical management |
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329 | (12) |
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18.1 Intrauterine growth restriction: placental basis and implications for clinical practice |
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341 | (14) |
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18.2 Intrauterine growth restriction: differential diagnosis and management |
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355 | (15) |
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19.1 Congenital diaphragmatic hernia: pathophysiology |
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370 | (6) |
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19.2 Congenital diaphragmatic hernia: clinical antenatal management |
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376 | (13) |
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20.1 Fetal stem cell transplantation: stem cell biology basics |
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389 | (8) |
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20.2 Fetal stem cell transplantation: clinical potential |
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397 | (10) |
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20.3 Fetal stem cell transplantation: fetal tissue engineering |
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407 | (10) |
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21 Gene therapy: physiological principles and clinical potential |
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417 | (16) |
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22 The future: fetal therapy and translational studies: global alignment, coordination, and collaboration in perinatal research: The Global Obstetrics Network (GONet) initiative |
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433 | (7) |
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Glossary |
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440 | (2) |
Index |
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442 | |