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El. knyga: Fetal Therapy: Scientific Basis and Critical Appraisal of Clinical Benefits

Edited by , Edited by (Baylor College of Medicine, Texas), Edited by
  • Formatas: EPUB+DRM
  • Išleidimo metai: 13-Dec-2012
  • Leidėjas: Cambridge University Press
  • Kalba: eng
  • ISBN-13: 9781139853835
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  • Formatas: EPUB+DRM
  • Išleidimo metai: 13-Dec-2012
  • Leidėjas: Cambridge University Press
  • Kalba: eng
  • ISBN-13: 9781139853835
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Kilby (fetal medicine, U. of Birmingham, UK), Johnson, and Oepkes provide maternal-fetal medicine and neonatology specialists and trainees with 22 chapters on the current status of fetal therapy. Fetal medicine, obstetrics and gynecology, pediatrics, reproductive medicine, and other specialists from Europe, North America, Australia, and Hong Kong consider aspects of transplacental therapy and both ultrasound and fetoscopic-directed interventions to treat fetal disease. They describe the pathogenesis of disease processes, treatment involving transplacental drug therapy, invasive procedures, and fetal surgery for various diseases, emphasizing treatments that have been established in clinical practice, reviewing the literature, and discussing why some therapy has failed to live up to its promise. The introductory section on general principles includes discussion of the ethics of in-utero therapy, the rationale for fetal therapy, human embryology, insights into the pathogenesis of adult cardiovascular disease from fetal animal studies, and risks, emotions, and the doctor's role in the decision-making process. Annotation ©2013 Book News, Inc., Portland, OR (booknews.com)

Recenzijos

'It is both scientific and pragmatic and should satisfy a variety of curiosities in this fascinating field of therapeutic medicine. As such, it is a "must have" for fetal medicine specialists and trainees, but also medical libraries.' The Obstetrician and Gynaecologist

Daugiau informacijos

Covers the latest insights any fetal specialist needs and provides essential knowledge for professionals caring for women with high-risk pregnancies.
List of contributors
ix
Foreword xiii
Charles Rodeck
Preface xv
Section 1 General principles
1 The rationale for fetal therapy
1(11)
Kenneth J. Moise Jr.
2 Insights into pathogenesis of adult cardiovascular disease from fetal animal studies
12(12)
Lucy R. Green
Mark A. Hanson
3 Human embryology: molecular mechanisms of embryonic disease
24(15)
Philippa Francis-West
Sana Zakaria
4 Ethics of fetal therapy
39(6)
Frank A. Chervenak
Laurence B. McCullough
5 Fetal therapy choices: about risks, emotions, and the doctor's role in the decision-making process
45(10)
Danielle R. M. Timmermans
Section 2 Fetal disease: pathogenesis and principles
6 Red cell alloimmunization
55(12)
Janet Brennand
Alan Cameron
7 Fetal and neonatal alloimmune thrombocytopenia
67(11)
Khadija Madani
Dick Oepkes
8.1 Fetal dysrhythmias: the effects of antiarrhythmic therapy on the immature heart
78(9)
Edgar Jaeggi
Nico A. Blom
Tara Bharucha
8.2 Fetal dysrhythmias: clinical management
87(13)
Julene S. Carvalho
9.1 Structural heart disease: embryology
100(13)
Adriana C. Gittenberger-de Groot
Monique R. M. Jongbloed
Robert E. Poelmann
Margot M. Bartelings
9.2 Structural heart disease: genetic influences
113(10)
Catherine L. Mercer
David I. Wilson
9.3 Structural heart disease: fetal cardiac interventions
123(5)
Wayne Tworetzky
Louise E. Wilkins-Haug
10.1 Manipulation of amniotic fluid volume: homeostasis of fluid volumes in the amniotic cavity
128(9)
Marie H. Beall
Michael G. Ross
10.2 Manipulation of amniotic fluid volume: oligohydramnios and polyhydramnios
137(8)
Tak Yeung Leung
Stephen Sik
Hung Suen
11.1 Twin-to-twin transfusion syndrome: scientific basis
145(11)
Caroline E. Fox
Enrico Lopriore
Mark D. Kilby
11.2 Twin-to-twin transfusion syndrome: placental circulation
156(10)
Geoffrey A. Machin
11.3 Twin-to-twin transfusion syndrome: cardiovascular manifestations
166(7)
Shari L. Wellen
Jack Rychik
11.4 Twin-to-twin transfusion syndrome: treatment by fetoscopic laser ablation
173(11)
Gihad E. Chalouhi
Abdullah Al Ibrahim
Mohammed Essaoui
Yves Ville
11.5 Twin-to-twin transfusion syndrome: management of stage I disease
184(3)
Ramesha Papanna
Kenneth J. Moise Jr.
12.1 Twin reversed arterial perfusion (TRAP) sequence: pathophysiology
187(6)
Martin A. Weber
Neil J. Sebire
12.2 Twin reversed arterial perfusion (TRAP) sequence: in-utero treatment
193(7)
Diana L. Farmer
Katrine M. Lofberg
13.1 Fetal infections: immune responses to congenital infections
200(8)
Ariane Huygens
Arnaud Marchant
13.2 Fetal infections: clinical management
208(30)
Guillaume Benoist
Marianne Leruez-Ville
Francois Jacquemard
Yves Ville
14.1 Fetal urinary tract obstruction: pathophysiology
238(8)
Robert L. Chevalier
14.2 Fetal urinary tract obstruction: prenatal assessment and prognosis
246(7)
Nahla Khalek
Mark P. Johnson
14.3 Fetal urinary tract obstruction: fetal cystoscopy
253(8)
Rodrigo Ruano
Anthony Johnson
Mark D. Kilby
14.4 Fetal urinary tract obstruction: in-utero intervention
261(10)
R. Katie Morris
Mark D. Kilby
15.1 Fetal lung growth, development, and lung fluid: physiology and pathophysiology
271(11)
Richard Harding
Foula Sozo
Takushi Hanita
Cheryl Albuquerque
15.2 Fetal lung growth, development, and lung fluid: clinical management of pleural effusion and pulmonary pathology
282(19)
Kirsten Grabowska
R. Douglas Wilson
16.1 Neural tube defects: pathophysiology and prevention
301(10)
Sarah Clements
Daniel Challis
Debra Kennedy
16.2 Neural tube defects: clinical management
311(9)
Leslie N. Sutton
17.1 Fetal tumors: pathophysiology
320(9)
Martin A. Weber
Neil J. Sebire
17.2 Fetal tumors: clinical management
329(12)
Sundeep G. Keswani
Timothy M. Crombleholme
18.1 Intrauterine growth restriction: placental basis and implications for clinical practice
341(14)
John Kingdom
Melissa Walker
Sascha Drewlo
Sarah Keating
18.2 Intrauterine growth restriction: differential diagnosis and management
355(15)
Fergus P. McCarthy
John Kingdom
19.1 Congenital diaphragmatic hernia: pathophysiology
370(6)
Nicola A. Lewis
Philip L. Glick
19.2 Congenital diaphragmatic hernia: clinical antenatal management
376(13)
Jan Deprest
Jaan Toelen
Philip De Koninck
Jute Richter
Alexander Engels
Paul Brady
Kypros Nicolaides
Eduard Gratacos
Filip Claus
Dick Tibboel
Roland Devlieger
20.1 Fetal stem cell transplantation: stem cell biology basics
389(8)
Jon Frampton
20.2 Fetal stem cell transplantation: clinical potential
397(10)
Magnus Westgren
Cecilia Gotherstrom
20.3 Fetal stem cell transplantation: fetal tissue engineering
407(10)
Fabienne L. Gray
Dario O. Fauza
21 Gene therapy: physiological principles and clinical potential
417(16)
Vedanta Mehta
Anna L. David
22 The future: fetal therapy and translational studies: global alignment, coordination, and collaboration in perinatal research: The Global Obstetrics Network (GONet) initiative
433(7)
Ben W. Mol
Mark D. Kilby
Glossary 440(2)
Index 442
Mark D. Kilby is Dame Hilda Lloyd Professor of Maternal and Fetal Medicine and Deputy Head of the School of Reproduction, Genes and Development, University of Birmingham, UK. Anthony Johnson is Professor of Maternal Fetal Medicine, University of Texas Health Science Center, Houston, TX, USA. Dick Oepkes is Professor of Obstetrics and Fetal Therapy, Leiden University Medical Centre, Leiden, The Netherlands.