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El. knyga: Fishman's Pulmonary Diseases and Disorders, 2-Volume Set, 5th edition

  • Formatas: 2400 pages
  • Išleidimo metai: 17-Apr-2015
  • Leidėjas: McGraw-Hill Professional
  • Kalba: eng
  • ISBN-13: 9781259589126
Kitos knygos pagal šią temą:
  • Formatas: 2400 pages
  • Išleidimo metai: 17-Apr-2015
  • Leidėjas: McGraw-Hill Professional
  • Kalba: eng
  • ISBN-13: 9781259589126
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Turn to the field's definitive text for a thorough understanding of the clinical and scientific aspects of pulmonary medicineA  Doody's Core Title for 2022!









Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the underlying basic and applied science upon which clinical practice is based. The Fifth Edition, with 270 contributing authors, includes over 2,000 illustrations, 60 videos, and 18,000 references. The book opens with a comprehensive overview of the scientific basis of lung function in health and disease. It then provides detailed coverage of the broad array of diseases and disorders affecting the respiratory system, including obstructive and restrictive diseases, pulmonary vascular disorders, sleep-disordered breathing, lung neoplasms,respiratory infections, and respiratory failure, among others.

The Fifth Edition has been completely updated to reflect the many advancements that have been made in pulmonary medicine over the past few years, including:





Molecular development of the lung Stem cells and respiratory disease Genetics of pulmonary disease and the growth of personalized medicine Technical advances in lung transplantation Growth in immunology and immunosuppressive management Diagnosis and treatment of pulmonary hypertension Circadian rhythms and sleep biology Rapid evolution in lung imaging techniques, including functional imaging Contemporary interventional bronchoscopic techniques





You will also find state-of-the-art coverage of the latest topics in critical care medicine, including:





Early diagnosis and management of sepsis Multiple organ dysfunction syndrome (MODS) Acute respiratory distress syndrome (ARDS) Management of agitation and delirium in the ICU The newly defined entity of "chronic critical illness"
Contributors xiii
Preface xxvii
VOLUME 1
PART 1 Perspectives
1 Milestones in the History of Pulmonary Medicine
2(18)
Michael A. Grippi
PART 2 Scientific Basis of Lung Function in Health and Disease
Section 1 Genetic, Cellular, and Structural Basis of Normal Lung Function
2 Functional Design of the Human Lung for Gas Exchange
20(43)
Matthias Ochs
Ewald R. Weibel
3 The Respiratory Muscles
63(10)
Ghislaine Gayan-Ramirez
Marc Decramer
4 Molecular Regulation of Lung Development
73(10)
Wellington V. Cardoso
Jining Lu
5 Pulmonary Surfactant and Disorders of Surfactant Homeostasis
83(10)
Jeffrey A. Whitsett
Timothy E. Weaver
6 Mucociliary Clearance
93(11)
Burton F. Dickey
Michael R. Knowles
Richard C. Boucher
7 The Genetic Basis of Respiratory Disorders
104(13)
Micheala A. Aldred
8 Stem Cells and Respiratory Disease: Prospects for the Future
117(7)
Darrell N. Kotton
9 Personalized Pulmonary Medicine
124(13)
Benjamin A. Raby
Kelan G. Tantisira
Section 2 Physiological Principles of Normal Lung Function
10 Pulmonary Mechanics
137(11)
Murray D. Altose
11 Control of Ventilation
148(10)
Frank J. Jacono
Xavier Soler
Atul Malhotra
12 Circadian Rhythms and Sleep Biology
158(9)
Allan I. Pack
13 Pulmonary Circulation
167(16)
Robert Naeije
14 Ventilation, Pulmonary Blood Flow, and Ventilation--Perfusion Relationships
183(12)
Peter D. Wagner
15 Blood-Gas Transport
195(4)
Adrian Shifren
Robert A. Klocke
16 Diffusion, Chemical Reactions, and Diffusing Capacity
199(8)
Robert A. Klocke
Adrian Shifren
17 Acid--Base Balance
207(12)
Stanley Goldfarb
Kumar Sharma
Section 3 The Lungs in Different Physiological States
18 Respiratory System Response to Exercise in Health
219(14)
Jerome A. Dempsey
Anthony J. Jacques
19 Aging of the Respiratory System
233(13)
Edward J. Campbell
Section 4 Lung Immunology
20 Innate and Adaptive Immunity in the Lung
246(13)
Charles S. Dela Cruz
Jonathan L. Koff
21 Lymphocyte- and Macrophage-Mediated Inflammation in the Lung
259(16)
Praveen Govender
Frederic F. Little
Kevin C. Wilson
David M. Center
22 Mast Cells and Eosinophils
275(17)
Edward S. Schulman
Peter H. S. Sporn
23 Leukocyte Accumulation in Pulmonary Disease
292(11)
Nicholas W. Lukacs
Peter A. Ward
24 Antibody-Mediated Lung Defenses and Humoral Immunodeficiency
303(15)
Homer L. Twigg
Section 5 Lung Injury and Repair
25 T Lymphocytes in the Lung
318(9)
Lauren E. Cohn
26 Chemokines, Adipokines, and Growth Factors in the Lung
327(14)
Marcus W. Butler
Paul McLoughlin
Michael P. Keane
27 Redox Signaling and Oxidative Stress in Lung Diseases
341(18)
Jessy Deshane
Victor J. Thannickal
28 Fibroblasts in Lung Homeostasis and Disease
359(15)
Yong Zhou
Victor J. Thannickal
PART 3 Symptoms and Signs of Respiratory Disease
Section 6 Clinical Approach to the Patient
29 Approach to the Patient with Respiratory Symptoms
374(38)
Michael A. Grippi
Robert M. Senior
Jeffrey P. Callen
Section 7 Diagnostic Procedures
30 Modern Approach to Thoracic Imaging Diagnosis
412(56)
Eduardo J. Mortani Barbosa Jr.
Warren B. Gefter
31 Thoracic Ultrasonography
468(9)
Lisa Chen
Paul H. Mayo
32 Physiologic and Metabolic Study of Pulmonary Disorders Using Conventional Imaging Techniques and Positron Emission Tomography
477(25)
Ghassan El-Haddad
Søren Hess
Daniel Worsley
Abass Alavi
33 Pulmonary Function Testing
502(35)
Michael A. Grippi
Gregory Tino
34 Principles and Applications of Cardiopulmonary Exercise Testing
537(16)
Karl T. Weber
Kevin P. Newman
35 Diagnostic Bronchoscopy, Transthoracic Needle Biopsy, and Related Procedures
553(19)
Anil Vachani
Daniel H. Sterman
36 Interventional Bronchoscopy
572(11)
Andrew R. Haas
Daniel H. Sterman
37 Diagnostic Thoracic Surgical Procedures: Thoracoscopy, VATS, and Thoracotomy
583(3)
Robert E. Merritt
38 Evaluation of Respiratory Impairment and Disability
586(14)
Akshay Sood
PART 4 Obstructive Lung Diseases
Section 8 Chronic Obstructive Pulmonary Disease
39 Pathology of Chronic Obstructive Pulmonary Disease: Diagnostic Features and Differential Diagnosis
600(13)
Joanne L. Wright
Andrew Churg
40 Chronic Obstructive Pulmonary Disease: Epidemiology, Pathophysiology, Pathogenesis, and α1-Antitrypsin Deficiency
613(23)
Robert M. Senior
Richard A. Pierce
Jeffrey J. Atkinson
41 Cigarette Smoking and Smoking Cessation
636(14)
Stephen I. Rennard
David M. Daughton
42 Course and Treatment of Chronic Obstructive Pulmonary Disease
650(14)
M. Bradley Drummond
Robert A. Wise
43 Rehabilitation in Chronic Obstructive Pulmonary Disease and Other Respiratory Disorders
664(9)
Andrew L. Ries
Section 9 Asthma
44 The Biology of Asthma
673(14)
Matthew C. Bell
William W. Busse
45 Asthma: Epidemiology
687(13)
Augusto A. Litonjua
Andrea J. Apter
Scott T. Weiss
46 Asthma: Clinical Presentation and Management
700(15)
Omar S. Usmani
Peter J. Barnes
47 Aspirin- and Exercise-Induced Asthma
715(15)
Jose L. Gomez
Geoffrey L. Chupp
Gregory P. Geba
48 Allergic Bronchopulmonary Aspergillosis (Mycosis) and Severe Asthma with Fungal Sensitivity
730(8)
Geoffrey L. Chupp
Section 10 Other Obstructive Disorders
49 Upper Airway Obstruction in Adults
738(19)
Christine Won
Gaetane Michaud
Meir H. Kryger
50 Cystic Fibrosis
757(21)
Judith A. Voynow
Maria Mascarenhas
Andrea Kelly
Thomas F. Scanlin
51 Bronchiolitis
778(9)
Gary R. Epler
52 Bullous Disease of the Lung
787(13)
Fernando J. Martinez
53 Bronchiectasis
800(10)
Alan F. Barker
Steven L. Brody
PART 5 Interstitial and Inflammatory Lung Diseases
Section 11 Immunologic and Interstitial Diseases
54 Interstitial Lung Disease: A Clinical Overview and General Approach
810(13)
Danielle Antin-Ozerkis
55 Systemic Sarcoidosis
823(19)
David R. Moller
Edward S. Chen
56 Idiopathic Pulmonary Fibrosis
842(17)
Robert M. Tighe
Eric B. Meltzer
Paul W. Noble
57 Idiopathic Interstitial Pneumonias Other Than Idiopathic Pulmonary Fibrosis
859(16)
Erica L. Herzog
Ami N. Rubinowitz
Mridu Gulati
58 Hypersensitivity Pneumonitis
875(8)
Alex H. Gifford
Richard I. Enelow
59 Radiation Pneumonitis
883(19)
Kenneth B. Roberts
Roy Decker
Sara Rockwell
60 Pulmonary Manifestations of the Collagen Vascular Diseases
902(17)
Gregory P. Cosgrove
Marvin I. Schwarz
61 Pulmonary Langerhans' Cell Histiocytosis
919(9)
Sergio Harari
Olga Torre
Talmadge E. King Jr.
Joel Moss
62 Pulmonary Lymphangioleiomyomatosis
928(11)
Angelo M. Taveira-DaSilva
Talmadge E. King Jr.
Joel Moss
63 Benign Metastasizing Leiomyoma
939(6)
Gustavo Pacheco-Rodriguez
Angelo M. Taveira-DaSilva
Joel Moss
64 Depositional Diseases of the Lungs
945(11)
Robert J. Homer
PART 6 Drug-Induced Lung Diseases
65 Pulmonary Toxicity Related to Chemotherapeutic Agents
956(19)
Lynn T. Tanoue
John McArdle
Jennifer Possick
66 Drug-Induced Pulmonary Disease Due to Nonchemotherapeutic Agents
975(19)
Hilary C. Cain
PART 7 Other Infiltrative and Airspace Disorders
67 The Lungs in Patients with Inborn Errors of Metabolism
994(7)
Timothy Craig Allen
68 Alveolar Hemorrhage Syndromes
1001(17)
Joseph P. Lynch
Michael C. Fishbein
Tisha Wang
69 Aspiration-Related Pulmonary Disorders
1018(10)
Paul E. Marik
70 Pulmonary Alveolar Proteinosis Syndrome
1028(9)
Bruce C. Trapnell
Takuji Suzuki
71 The Eosinophilic Pneumonias
1037(27)
Carolyn L. Rochester
PART 8 Disorders of the Pulmonary Circulation
72 Pulmonary Arterial Hypertension
1064(46)
Darren B. Taichman
Jess Mandel
Kimberly A. Smith
Jason X.-J. Yuan
73 Pulmonary Thromboembolic Disease
1110(24)
Peter F. Fedullo
Gordon L. Yung
74 Pulmonary Vasculitis
1134(14)
Ulrich Specks
75 Pulmonary Arteriovenous Malformations
1148(16)
Daniel M. Goodenberger
Murali Chakinala
VOLUME 2
PART 9 Disorders of the Pleural Space
76 Nonmalignant Pleural Effusions
1164(24)
John E. Heffner
77 Malignant Pleural Effusions
1188(9)
Steven A. Sahn
John T. Huggins
78 Pneumothorax
1197(19)
S. Rodrigo Burguete
Daniel T. DeArmond
Nilam J. Soni
Jay Peters
PART 10 Diseases of the Mediastinum
79 Malignant Mesothelioma and Other Primary Pleural Tumors
1216(20)
Edmund K. Moon
Leslie A. Litzky
Daniel H. Sterman
80 Nonneoplastic Disorders of the Mediastinum
1236(12)
Cameron D. Wright
81 Congenital Cysts of the Mediastinum: Bronchopulmonary Foregut Anomalies
1248(11)
Alberto de Hoyos
Malcolm M. DeCamp Jr.
82 Benign and Malignant Neoplasms of the Mediastinum
1259(15)
Bryan M. Burt
Joseph B. Shrager
PART 11 Disorders of the Chest Wall, Diaphragm, and Spine
83 Nonmuscular Diseases of the Chest Wall
1274(15)
George E. Tzelepis
F. Dennis McCool
84 Effects of Neuromuscular Diseases on Ventilation
1289(24)
Gerard J. Criner
Nathaniel Marchetti
85 Management of Neuromuscular Respiratory Muscle Dysfunction
1313(9)
John R. Bach
PART 12 Occupational and Environmental Disorders
Section 12 Occupational Disorders
86 Asbestos-Related Lung Disease
1322(12)
William N. Rom
87 Chronic Beryllium Disease and Hard-Metal Lung Diseases
1334(8)
Mary Elizabeth Kreider
Milton D. Rossman
88 Coal Workers' Lung Diseases and Silicosis
1342(18)
Robert C. Stansbury
Edward L. Petsonk
John E. Parker
89 Occupational Asthma, Byssinosis, and Industrial Bronchitis
1360(9)
J. Allen
D. Cooper
90 Acute and Chronic Responses to Toxic Inhalations
1369(17)
Jian Jing
David A. Schwartz
Section 13 Environmental Disorders
91 Indoor and Outdoor Air Pollution
1386(26)
David Q. Rich
Jonathan M. Samet
Mark J. Utell
92 High-Altitude Physiology and Clinical Disorders
1412(8)
Kingman P. Strohl
Cynthia M. Beall
Nikolaus C. Netzer
93 Diving Injuries and Air Embolism
1420(8)
Christopher Logue
94 Thermal Lung Injury and Acute Smoke Inhalation
1428(14)
Perenlei Enkhbaatar
PART 13 Pulmonary Complications of Nonpulmonary Disorders
95 Noninfectious Pulmonary Complications of Hematopoietic Stem Cell and Solid Organ Transplantation
1442(21)
Bekele Afessa
Steve G. Peters
Robert M. Kotloff
96 Pulmonary Complications of Sickle Cell Disease
1463(16)
Roberto F. Machado
Mark T. Gladwin
97 Pulmonary Disorders and Pregnancy
1479(17)
Ghada Bourjeily
Jeffrey Mazer
Andrew Levinson
98 Pulmonary Complications of Intra-abdominal Disease
1496(14)
Sonja D. Bartolome
Michael J. Krowka
PART 14 Sleep and Sleep Disorders
99 Sleep Apnea Syndromes: Central and Obstructive
1510(41)
Grace W. Pien
Ilene M. Rosen
Barry G. Fields
100 Sleep-Related Hypoventilation Syndromes
1551(10)
Richard J. Schwab
Bernie Young Sunwoo
101 Changes in the Cardiorespiratory System During Sleep
1561(6)
Indira Gurubhagavatula
102 Differential Diagnosis and Evaluation of Sleepiness
1567(11)
Mithu Sen
Meir H. Kryger
PART 15 Surgical Aspects of Pulmonary Medicine
103 Perioperative Respiratory Considerations in the Surgical Patient
1578(14)
Horace M. DeLisser
Michael A. Grippi
104 Acute Respiratory Failure in the Surgical Patient
1592(14)
Robert M. Kotloff
105 Perioperative Care of the Patient Undergoing Lung Resection
1606(12)
Robert J. Cerfolio
Ayesha S. Bryant
106 Thoracic Trauma
1618(6)
Nathan T. Mowery
J. Wayne Meredith
107 Lung Transplantation
1624(28)
Allan R. Glanville
PART 16 Neoplasms of the Lungs
Section 14 Lung Cancer
108 Genetic and Molecular Changes in Lung Cancer: Prospects for a Personalized Pharmacological Approach to Treatment
1652(15)
Howard Li
Jeffrey A. Kern
109 Epidemiology of Lung Cancer
1667(17)
Charles S. Dela Cruz
Lynn T. Tanoue
Richard A. Matthay
110 Approach to the Patient with Pulmonary Nodules
1684(16)
David Ost
111 The Pathology of Bronchogenic Carcinoma
1700(22)
Leslie A. Litzky
112 Clinical Evaluation, Diagnosis, and Staging of Lung Cancer
1722(11)
Lydia Chang
M. Patricia Rivera
113 Treatment of Non--Small-Cell Lung Cancer: Surgery
1733(14)
Scott I. Reznik
W. Roy Smythe
114 Treatment of Non--Small-Cell Lung Cancer: Chemotherapy
1747(11)
Laurie L. Carr
James R. Jett
115 Treatment of Non--Small-Cell Lung Cancer: Radiation Therapy
1758(12)
Tithi Biswas
Mitchell Machtay
116 Small Cell Lung Cancer: Diagnosis, Treatment, and Natural History
1770(16)
Jonathan E. Dowell
David E. Gerber
David H. Johnson
117 Primary Lung Tumors Other than Bronchogenic Carcinoma: Benign and Malignant
1786(11)
Alla Godelman
Steven M. Keller
118 Extrapulmonary Syndromes Associated with Lung Tumors
1797(13)
Nicholas J. Pastis
Nichole T. Tanner
Gerard A. Silvestri
119 Pulmonary Metastases: The Role of Surgical Resection
1810(6)
Loretta Erhunmwunsee
Thomas A. D'Amico
Section 15 Lymphoproliferative Disorders
120 Lymphoproliferative and Hematologic Diseases Involving the Lung and Pleura
1816(24)
Douglas B. Flieder
PART 17 Infectious Diseases of the Lungs
Section 16 General Concepts
121 Pulmonary Clearance of Infectious Agents
1840(13)
Theodore J. Standiford
Galen B. Toews
Gary B. Huffnagle
122 Approach to the Patient with Pulmonary Infection
1853(27)
Jay A. Fishman
123 Pulmonary Infection in Immunocompromised Hosts
1880(36)
Jay A. Fishman
124 Microbial Virulence Factors in Pulmonary Infections
1916(6)
Gregory P. Priebe
Gerald B. Pier
125 Principles of Antibiotic Use and the Selection of Empiric Therapy for Pneumonia
1922(15)
Bala Prakash
Michael S. Niederman
Section 17 Common Syndromes in Pulmonary Infectious Diseases
126 Infections of the Upper Respiratory Tract
1937(12)
Thomas M. File Jr.
127 Aspiration, Empyema, Lung Abscesses, and Anaerobic Infections
1949(17)
Kyle B. Enfield
Costi D. Sifri
128 Acute Bronchitis and Community-Acquired Pneumonia
1966(15)
Thomas J. Marrie
129 Healthcare-Acquired Pneumonia, Including Ventilator-Associated Pneumonia
1981(11)
Anthony F. Boyer
Marin H. Kollef
Section 18 Major Pathogens in Pulmonary Infections
130 Viral Infections of the Lung and Respiratory Tract
1992(20)
John Treanor
131 Tuberculosis
2012(20)
Karen Doucette
Ryan Cooper
132 Diseases due to Nontuberculous Mycobacteria
2032(7)
Julie V. Philley
Richard J. Wallace Jr.
133 Aspergillus, Candida, and Other Opportunistic Mold Infections of the Lung
2039(30)
Georgios Chamilos
Dimitrios P. Kontoyiannis
134 Cryptococcosis and the Endemic Mycoses
2069(24)
L. Joseph Wheat
Mitchell Goldman
Chadi A. Hage
Kenneth S. Knox
135 Pneumocystis Pneumonia
2093(18)
Stanley I. Martin
Jay A. Fishman
136 Protozoan Infections of the Thorax
2111(12)
Louise C. Ivers
Edward T. Ryan
137 Helminthic Diseases of the Lungs
2123(12)
Alissa Jade Wright
Jay A. Fishman
138 Zoonotic and Other Unusual Bacterial Pneumonias
2135(17)
Camille Nelson Kotton
Arnold N. Weinberg
PART 18 Acute Respiratory Failure
139 Respiratory Failure: An Overview
2152(10)
Michael A. Grippi
Section 19 Lung Failure
140 Acute Respiratory Distress Syndrome: Pathogenesis
2162(10)
Asha N. Chesnutt
Michael A. Matthay
141 Acute Lung Injury and the Acute Respiratory Distress Syndrome: Clinical Features, Management, and Outcomes
2172(24)
John P. Reilly
Jason D. Christie
142 Sepsis, Multiple Organ Dysfunction Syndrome, and Chronic Critical Illness
2196(8)
Emily K. B. Gordon
Clifford S. Deutschman
Section 20 Respiratory Pump Failure
143 Pump Failure: The Pathogenesis of Hypercapnic Respiratory Failure in Patients with Lung and Chest Wall Disease
2204(18)
Steven G. Kelsen
Section 21 Management and Therapeutic Interventions
144 Oxygen Therapy and Toxicity
2222(15)
Matthew Wemple
Joshua O. Benditt
145 Pulmonary Pharmacotherapy
2237(17)
Karen J. Tietze
Scott Manaker
146 Intubation and Upper Airway Management
2254(11)
C. William Hanson
Erica R. Thaler
147 Hemodynamic and Respiratory Monitoring in Acute Respiratory Failure
2265(13)
Patrick J. Neligan
Barry D. Fuchs
148 Principles of Mechanical Ventilation
2278(14)
Martin J. Tobin
149 Nutrition in Pulmonary Disease
2292(8)
David S. Seres
150 Diagnosis and Treatment of Pain, Agitation, and Delirium in the Intensive Care Unit
2300(14)
Nathan E. Brummel
Timothy D. Girard
151 Early Mobilization of Patients in the ICU
2314(6)
William D. Schweickert
152 Organization of Intensive Care Units and Long-Term Acute Care Hospitals
2320(7)
Mark E. Mikkelsen
Barry D. Fuchs
Michael A. Grippi
153 Ethics and Palliative Care in Critical Care Units
2327
Joshua B. Kayser
Horace M. DeLisser
APPENDIXES
Appendix A Terms and Symbols in Respiratory Physiology
2(3)
Appendix B Normal Values for a Healthy 20-Year Old Seated Man
5
Index 1
Michael Grippi, MD is Associate Professor of Medicine at the University of Pennsylvania and Chief Medical Officer, Good Shepherd Penn Partners Specialty Hospital.

Jack Elias, MD is Dean of Medicine and Biological Sciences at Brown University.

Jay Fishman, MD is Associate Director, Mass General Transplant Center and Director, Transplant Infectious Diseases and Compromised Host Program.

Robert Kotloff, MD is Chairman of the Department of Pulmonary Medicine at the Cleveland Clinic.

Alan Pack, MD, PhD Professor of Medicine at the University of Pennsylvania.

Robert Senior, MD is Professor of Pulmonary Diseases, Medicine and Professor, Cell Biology and Physiology at Washington University School of Medicine.