This volume is a practical guide of theranostics using intraoperative fluorescence imaging technology, as an all-out effort by the Japanese Society for Fluorescence Guided Surgery. It describes the various approaches the technique is being used such as vascular imaging, identification of lymphatic vessels by intratissue injection, lymph node imaging, and imaging for identification of anatomical structures. The book is organized into three major parts and the first one delivers the basics, introducing the use of the technology in clinical settings and initial setups. Next comes the description of clinical applications where chapters illustrate perfusion assessment, cancer localization, anatomy visualization, and lymph nodes/ducts mapping. Each chapter is devoted to the specific surgical field and disease areas, presenting images and videos of case studies. The last part presents some upcoming techniques for treatments. The Editor and the authors wish the ideas presented here will behints to bridge the knowledge between surgeons and basic researchers for further innovation and practicality. It is important to stay up-to-date since intraoperative fluorescence imaging has been applied to clinical settings in various surgical fields and at the same time, novel techniques improving the efficacy of the technology have also been developed actively.
Fluorescence-Guided Surgery From Lab to Operation Room is recommended for surgeons, operating nurses, medical experts, basic researchers and, industry engineers worldwide beyond boundaries of specialties. Edited and written by experts of The Japanese Society for Fluorescence-Guided Surgery, those who are the founders of the technology, it describes the accurate development history and cutting-edge techniques based on the knowledge accumulated over the years.
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Part IBasics of intraoperative fluorescence imaging
[ Introduction].- Chapter 1 Clinically available fluorescent
reagents.- Chapter 2 ICG fluorescence imaging system for open
surgery.- Chapter 3 ICG fluorescence imaging system for endoscopic surgery
and robot-assisted surgery.- Chapter 4 5-ALA fluorescence imaging
system.- Chapter 5 How to introduce fluorescence imaging to the operating
room.- Chapter 6 Recording of intraoperative fluorescence imaging.- Part
IIIntraoperative Fluorescence Imaging [ Practice] - Perfusion
assessment.- Chapter 7 Introduction.- Chapter 8 Coronary
angiography.- Chapter 9 Cerebral angiography (cerebral aneurysm).- Chapter 10
Evaluation of blood perfusion in skin flaps.
Chapter 11 Evaluation of blood
perfusion in the upper gastrointestinal tract.- Chapter 12 Evaluation of
blood perfusion in colorectal surgery.- Chapter 13 Perfusion assessment in
HBP surgery and liver transplantation.- Part III Intraoperative Fluorescence
Imaging [ Practice] - Imaging of cancer.- Chapter 14 Liver cancer (primary
liver cancer, metastatic liver cancer).- Chapter 15 Lung cancer (marking the
tumor site).- Chapter 16 Gastric cancer (primary tumor, peritoneal
dissemination).- Chapter 17 Brain tumor.- Chapter 18 Bladder cancer.- Part
IV Intraoperative Fluorescence Imaging [ Practice] - Imaging of lymph nodes
and lymph vessels.- Chapter 19 Introduction.- Chapter 20 Identification of
sentinel lymph nodes in breast cancer surgery.- Chapter 21 Identification of
sentinel lymph nodes in gastric cancer surgery.- Chapter 22Identification of
sentinel lymph nodes in colorectal cancer surgery.- Chapter 23 Identification
of sentinel lymph nodes in gynecologic surgery.- Chapter 24 Lymphography and
evaluation of lymphedema.- Part V Intraoperative Fluorescence Imaging
[ Practice] - Imaging of anatomical structures.- Chapter 25 Imaging of the
bile ducts (fluorescence cholangiography).- Chapter 26 Hepatic
segmentation.- Chapter 27 Lung segmentation.- Chapter 28 Visualization of the
ureter.- Chapter 29 Imaging of the parathyroid gland.- Part VI Intraoperative
Fluorescence Imaging in Practice [ Development].- Chapter 30 Development of
novel fluorescent probes - Rapid Intraoperative Visualization of
Microcarcinoma by Local Application of Chemical Fluorescence Probes.- Chapter
31 Development of a new imaging system.- Chapter 32 Development of a new
operating room that integrates imaging information.- Chapter 33 Therapeutic
applications (1): Photodynamic therapy using porphyrin compounds.- Chapter 34
Application to therapy (2): Photoimmunotherapy using a near-infrared
fluorescent probe.
Takeaki Ishizawa, MD, PhD, FACSDepartment of Hepatobiliary-Pancreatic Surgery,Graduate School of Medicine, Osaka Metropolitan UniversityOsakaJapan Editorial Supervisor: Japanese Society for Fluorescence Guided Surgery (JSFGS)
