Treating solid organ cancers rely on accurate visualizing, biopsy sampling, and delivery of therapy targeted to the area which requires it. Ahmed (surgery and interventional science, U. College London) and other UK and US specialists argue for a paradigm change to treat often multifocal prostate cancer in this way. International contributors discuss the role for focal therapy in maximizing survival while minimizing morbidity; focal therapy and minimally-invasive therapies instead of radical prostatectomy to achieve that balance; considerations in conservative management; new trends in imaging and treatment options (e.g., the latest cryoablation techniques, photodynamic therapy for focal ablation); factors that affect patients' choice of treatments; and assessment of treatment efficacy. The volume includes scan images and color plates. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com)
This book comprehensively reviews the potential of focal therapy and discusses why the changing face of prostate cancer warrants a change in the way we treat men with the disease. It deals with the mechanisms by which disease can be localized within the gland and then the different technologies used for focal ablation. Bringing together eminent contributors in one accessible reference, this book introduces focal therapy to all urologists, oncologists, and radiologists who are involved in the treatment of men with prostate cancer.
Recenzijos
Whilst the book is not designed to represent a daily reference guide for the majority of the urological fraternity, it clearly does what it sets out to do; provide an up-to-date and comprehensive analysis of a treatment option that perhaps one day we will routinely consider alongside active surveillance and robotic surgery. (Urology News, 1 November 2012) Fokaltherapie bedeutet Heilung und Organerhalt bei Männern mit lokal begrenztem Prostatakarzinom. Von einem internationalen Team führender Urologen, Onkologen, Radiologen und Pathologen geschrieben, bietet dieses Handbuch einen umfassenden evidenzbasierten Überblick über diese aufsehenerregende neue Therapieform.
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| Preface |
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Section I Is there a role for Focal Therapy in Localised Prostate Cancer? |
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1 | (36) |
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1 The Rationale for Focal Therapy of Prostate Cancer |
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3 | (8) |
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2 Factors That Affect Patients' Choice of Treatment |
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11 | (6) |
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3 Histological Trends and the Index Lesion in Localized Prostate Cancer |
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17 | (12) |
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4 Selection Criteria for Prostate Cancer Focal Therapy |
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29 | (8) |
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Section II How can we accurately locate cancer within the gland? |
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37 | (48) |
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5 Localisation of Cancer within the Gland: Biopsy Strategies |
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39 | (8) |
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6 Localisation of Cancer within the Gland: Ultrasound Imaging |
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47 | (8) |
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7 Localization of Cancer within the Prostate: Dynamic Contrast-Enhanced MRI |
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55 | (11) |
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8 Localization of Cancer within the Gland: Diffusion-Weighted Magnetic Resonance Imaging of the Prostate |
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66 | (9) |
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9 The future of Molecular and Biomolecular Imaging in Prostate Cancer |
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75 | (10) |
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Section III How can we create discrete tissue necrosis? |
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85 | (58) |
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10 Energies for Focal Ablation: Cryoablation |
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87 | (11) |
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11 Focal Salvage Cryoablation in Recurrent Prostate Cancer |
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98 | (8) |
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12 High-Intensity Focused Ultrasound |
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106 | (8) |
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13 Energies for Focal Ablation: Photodynamic Therapy |
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114 | (12) |
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14 Focal Therapy for Prostate Cancer Using Radiation |
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126 | (6) |
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15 Image Registration and Fusion for Image-Guided Focal Ablation |
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132 | (11) |
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Section IV How can we determine the success of Focal Therapy? |
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143 | (36) |
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16 Determining Success of Focal Therapy: Biochemical and Biopsy Strategies |
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145 | (8) |
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17 Determining Success of Focal Therapy: Imaging |
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153 | (17) |
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18 Evaluating Focal Therapy: Future Perspectives |
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170 | (9) |
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| Index |
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| Colour plate section can be found facing page |
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116 | |
Edited by Hashim U. Ahmed, Division of Surgery and Interventional Science, University College London, London, UK Manit Arya, Department of Urology, University College London, London, UK
Peter R. Carroll, Department of Urology, University of California, San Francisco, CA, USA
Mark Emberton, Division of Surgery and Interventional Science, University College London, London, UK
