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Genetic Basis of Common Diseases 2nd Revised edition [Kietas viršelis]

Edited by (Professor of Medicine and Pediatrics, University of Minnesota), Edited by (Professor of Medical Genetics, University of Washington), Edited by (Professor of Medicine and Pediatrics, Cedars-Sinai Medical Center and University of California, Los Angeles)
  • Formatas: Hardback, 1096 pages, aukštis x plotis x storis: 222x286x46 mm, weight: 2441 g, numerous black and white photographs, figures and tables
  • Serija: Oxford Monographs on Medical Genetics 44
  • Išleidimo metai: 28-Nov-2002
  • Leidėjas: Oxford University Press Inc
  • ISBN-10: 0195125827
  • ISBN-13: 9780195125825
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 1096 pages, aukštis x plotis x storis: 222x286x46 mm, weight: 2441 g, numerous black and white photographs, figures and tables
  • Serija: Oxford Monographs on Medical Genetics 44
  • Išleidimo metai: 28-Nov-2002
  • Leidėjas: Oxford University Press Inc
  • ISBN-10: 0195125827
  • ISBN-13: 9780195125825
Kitos knygos pagal šią temą:
Nearly 90 percent of the 117 international specialists contributing to this new edition are new to the text, which has expanded from the original 46 chapters to 55. The 1992 text has been almost completely rewritten, reflecting advances in diseases whose genetic knowledge was rudimentary ten years ago. New chapters on specific diseases cover gallstones, hemochromatosis, osteoporosis, spondyloarthrophies, lupus erythematosis, mental retardation, common skin diseases and skin cancer, prostate cancer, hearing loss, and migraine. New general chapters cover genetic counseling, evolution and disease, genetic effects of therapy, pharmacogentics, and the role of mitochondrial variation. Annotation (c) Book News, Inc., Portland, OR (booknews.com)

Since the first edition of this highly acclaimed text was published in 1992, much new knowledge has been gained about the role of genetic factors in common adult diseases, and we now have a better understanding of the molecular processes involved in genetic susceptibility and diseases mechanisms. The second edition fully incorporates these advances. The entire book has been updated and twelve new chapters have been added. Most of these chapters deal with diseases such as gallstones, osteoporosis, osteoarthritis, skin cancer, other common skin diseases, prostate cancer and migraine headaches that are seen by all physicians. Others address the genetic and molecular basis of spondylarthropathies, lupus, hemochromatosis, IgA deficiency, mental retardation, hearing loss, and the role of mitochondrial variation in adult diseases. Chapters on the evolution of human genetic disease and on animal models add important background on the omplexities of these diseases. Unique clinical applications of genetics to common diseases are covered in the additional new chapters on genetic counseling, pharmacogenetics, and the genetic consequences of modern therapeutics.

Recenzijos

This book is an excellent starting point for clinicians, clinical geneticists and epidemiologists to cover the principles and specifics on the genetic aspect of common diseases of the Western world. For any of the diseases described, it will give the reader a basis from which to launch into a more in depth study. * Human Genetics * This book has no peer and this second edition will deservedly become a classic. * Doody's Journal * This text follows the tradition of excellence of the Oxford Monographs in Medical Genetics. * Neuromuscular Disorders * The Genetic Basis of Common Diseases is an excellent compilation of current knowledge... I use this fine book daily and look forward to subsequent editions. * Journal of the American Medical Association *

Daugiau informacijos

The only comprehensive volume on genetic factors in common adult diseases
PART 1: APPROACHES ;
1. Approach to Genetic Bases of Common Diseases ;
2. Molecular Genetics of Common Diseases ;
3. Genetic Epidemiologic Methods ;
4. Evolution of Human Genetic Diseases ;
5. Animal Models of Complex Genetic
Disease ;
6. Genetic Counselling: History, Risk Assessment, Strategies and
Ethical Considerations ; PART 2: CARDIOPULMONARY DISEASES ;
7. Genetics of
Coronary Atherosclerosis ;
8. Hypertension ;
9. Chronic Obstructive Pulmonary
Disease ; PART 3: IMMUNOLOGIC AND INFECTIOUS DISEASES ;
10. Genetics of Human
Susceptibility to Infectious Diseases: Progress and Prospects ;
11. Genetics
of Asthma and Bronchial Hyperresponsiveness ;
12. IgA Deficiency and Common
Variable Immunodeficiency ; PART 4: GASTROINTESTINAL DISORDERS ;
13. Peptic
Ulcer and Gastritis ;
14. Lactase Deficiency: Biological and Medical Aspects
of the Adult Human Lactase Polymorphism ;
15. Inflammatory Bowel Disease ;
16. Gallstones ;
17. Chronic Liver Disease ;
18. Hereditary Hemochromatosis ;
19. Gluten-Sensitive Enteropathy ; PART 5: ENDOCRINE DISORDERS ;
20. Thyroid
Disease ;
21. Type 1 Diabetes Mellitus ;
22. Type 2 Diabetes Mellitus ;
23.
Obesity ;
24. Genetics of Osteoporosis ;
25. Hyperuricemia and Gout ; PART 6:
GENITOURINARY DISEASES ;
26. Gynaecologic Disorders ;
27. Infertility and
Pregnancy Loss ; PART 7: RHEUMATOLOGIC DISEASES ;
28. Immunology and
Immunogenetics ;
29. Rheumatoid Arthritis ;
30. Seronegative
Spondyloarthropathies ;
31. Genetics of Systematic Lupus Erythematosus ;
32.
Genetic Basis of Primary Osteoarthritis ;
33. Common Disorders of Connective
Tissue ; PART 8: CANCER ;
34. Gastrointestinal Cancer ;
35. Breast Cancer ;
36. Familial and Genetic Influences on Risk of Lung Cancer ;
37. Reproductive
Organ Cancers ;
38. Skin Cancer ;
39. Prostate Cancer ;
40. Haematologic
Cancer ; PART 9: NEUROPSYCHIATRIC DISORDERS ;
41. Epilepsy ;
42. Multiple
Sclerosis ;
43. Alzheimer's Disease ;
44. Affective Disorders ;
45.
Schizophrenia ;
46. Alcoholism ;
47. Mental Retardation ;
48. Hereditary
Hearing Loss ;
49. Migraine ; PART 10: OTHER COMMON PROBLEMS ;
50. Common
Skin Disease ;
51. Genetic Modulation of Aging and Longevity ;
52.
Mitochondrial Defects in Common Diseases ;
53. Constitutional Chromosome
Disorders in Adults ; PART 11: THERAPY ;
54. Genetic Consequences of Modern
Therapeutics: Iatrogenic Mutagenesis ;
55. Pharmacogenetics, Ecogenetics and
Pharmacogenomics