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  • Formatas: 292 pages
  • Išleidimo metai: 16-Mar-2016
  • Leidėjas: National Academies Press
  • Kalba: eng
  • ISBN-13: 9780309380423

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For the United States, the 1991 Persian Gulf War was a brief and successful military operation with few injuries and deaths. However, soon after returning from duty, a large number of veterans began reporting health problems they believed were associated with their service in the Gulf. At the request of Congress, the Institute of Medicine (IOM) has been conducting an ongoing review of the evidence to determine veterans' long-term health problems and potential causes. The fourth volume in the series, released in 2006, summarizes the long-term health problems seen in Gulf War veterans. In 2010, the IOM released an update that focuses on existing health problems and identifies possible new ones, considering evidence collected since the initial summary.



Gulf War and Health: Volume 10 is an update of the scientific and medical literature on the health effects associated with deployment to the Gulf War that were identified in Volumes 4 and 8. This report reviews and evaluates the associations between illness and exposure to toxic agents, environmental or wartime hazards, or preventive measures and vaccines associated with Gulf War service, and provides recommendations for future research efforts on Gulf War veterans.

Table of Contents



Front Matter Summary 1 Introduction 2 Considerations in Identifying and Evaluating the Literature 3 Human Cohort Studies and Their Derivatives 4 Evaluation of Health Conditions 5 Animal Studies 6 Findings and Recommendations 7 References Appendix: Committee Biographies
Preface ix
Acronyms and Abbreviations xiii
Summary 1(12)
Charge to the Committee
2(1)
The Committee's Approach
2(2)
Major Cohort Studies
4(1)
Health Outcomes
5(1)
Animal Studies
5(1)
Findings and Recommendations
5(5)
Moving Forward
10(3)
1 Introduction
13(12)
The Gulf War Setting
14(4)
The Gulf War Aftermath
18(3)
Charge to the Committee
21(1)
Committee's Approach to Its Charge
22(1)
Organization of the Report
22(3)
2 Considerations In Identifying And Evaluating The Literature
25(12)
Identification of the Literature
25(1)
Evaluation Process
26(5)
Individual Variability
31(1)
Exposure Assessment
31(2)
Categories of Association
33(1)
Conclusions
34(3)
3 Human Cohort Studies and Their Derivatives
37(30)
Organization of This
Chapter
38(1)
U.S. Veteran Cohorts
38(17)
United Kingdom Veteran Studies
55(4)
Australian Veteran Studies
59(2)
Danish Peacekeeper Studies
61(1)
Canadian Veterans Studies
62(1)
Summary
62(5)
4 Evaluation of Health Conditions
67(150)
Gulf War Illness
68(23)
Cancer
91(9)
Blood and Circulatory System Conditions
100(9)
Endocrine and Metabolic Conditions
109(6)
Mental and Behavioral Health Conditions
115(13)
Neurologic Conditions
128(23)
Respiratory System Conditions
151(7)
Gastrointestinal System Conditions
158(6)
Chronic Skin Conditions
164(4)
Pain-Related Conditions
168(12)
Genitourinary System Conditions
180(6)
Adverse Reproductive and Perinatal Outcomes
186(8)
Causes of Mortality
194(21)
Health Conditions Related to Depleted Uranium Exposure
215(2)
5 Animal Studies
217(22)
Animal Models of Gulf War Illness
218(1)
Blood--Brain Barrier Permeability, Brain Histopathology, and Brain Metabolism and Function
218(4)
Behavioral Effects
222(5)
Organ System Effects
227(1)
Conclusions
228(11)
6 Findings and Recommendations
239(12)
Summary of Findings
240(2)
Gulf War Illness
242(2)
Neurological Conditions
244(1)
Lung and Brain Cancer
245(1)
Other Health Conditions
246(1)
Exposure Assessments
247(1)
Sex, Race, and Ethnicity
248(1)
Moving Forward
249(2)
7 References
251(20)
Appendix: Committee Biographies 271