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Haematology: A Core Curriculum [Minkštas viršelis]

(Imperial College London, Uk)
  • Formatas: Paperback / softback, 348 pages
  • Išleidimo metai: 27-Aug-2010
  • Leidėjas: Imperial College Press
  • ISBN-10: 1848164998
  • ISBN-13: 9781848164994
Kitos knygos pagal šią temą:
  • Formatas: Paperback / softback, 348 pages
  • Išleidimo metai: 27-Aug-2010
  • Leidėjas: Imperial College Press
  • ISBN-10: 1848164998
  • ISBN-13: 9781848164994
Kitos knygos pagal šią temą:
This textbook is written by a renowned haematologist with more than 30 years of experience in teaching haematology to medical students and whose pedagogical and writing skills are widely admired within the field. Following closely the current curriculum of Imperial College London, medical students, trainee nurses and biomedical science students from other institutions will find the textbook equally suitable, since it includes the core student haematology curriculum as recommended by the Royal College of Pathologists and the British Society of Haematology expert group. This text will be equally suitable for students outside the UK.

The textbook takes a useful, practical approach, incorporating self-evaluation questions and learning objectives that give students not only the information needed to understand the topic but also clear indications on the core knowledge that students are required to know in order to progress within the field of haematology.

This textbook is written by a renowned haematologist with more than 30 years of experience in teaching haematology to medical students and whose pedagogical and writing skills are widely admired within the field. Following closely to the current curriculum of the Imperial College London, medical students, trainee nurses and biomedical students from other institutions will find the textbook equally suitable, since it includes the core student haematology curriculum as recommended by the Royal College of Pathologists.The textbook takes a useful, practical approach, incorporating self-evaluation questions and learning objectives that give students not only the information needed to understand the topic but also clear indications on the core knowledge that students are required to know in order to progress within the field of haematology.
Preface xi
1 Physiology of the Blood and Bone Marrow
1(19)
Blood Cells and Their Functions
1(6)
Bone Marrow Cells and Normal Haemopoiesis
7(12)
Conclusions
19(1)
2 The Blood Count and Film
20(21)
The Full Blood Count
20(4)
The Differential White Cell Count
24(1)
Haematological Terminology
25(1)
Normal Ranges and Reference Ranges
26(10)
How to Interpret a Blood Count and Develop a Differential Diagnosis
36(4)
The Erythrocyte Sedimentation Rate
40(1)
Conclusions
40(1)
3 Microcytic Anaemias and the Thalassaemias
41(22)
Introduction
41(2)
Iron Deficiency Anaemia
43(6)
Anaemia of Chronic Disease
49(3)
The Thalassaemias
52(8)
Other Causes of Microcytic Anaemia
60(1)
Conclusions
61(2)
4 Macrocytic Anaemias
63(14)
Introduction
63(2)
Vitamin B12 Deficiency
65(5)
Folic Acid Deficiency
70(2)
Other Causes of Macrocytosis
72(4)
Conclusion
76(1)
5 Haemoglobinopathies and Haemolytic Anaemias
77(27)
Introduction
78(3)
Mechanisms of Haemolysis
81(1)
Diagnosis of Haemolysis
82(1)
The Haemoglobinopathies
83(10)
Red Cell Membrane Defects
93(4)
Defects in the Glycolytic Pathway
97(1)
Defects in the Pentose Shunt
97(3)
Immune Haemolytic Anaemias
100(1)
Microangiopathic Haemolytic Anaemia
101(1)
Conclusions
101(3)
6 Miscellaneous Anaemias, Pancytopenia and the Myelodysplastic Syndromes
104(17)
Normocytic Normochromic Anaemia and Other Miscellaneous Anaemias
104(3)
Pancytopenia
107(5)
The Myelodysplastic Syndromes
112(7)
Conclusions
119(2)
7 Leucocytosis, Leucopenia and Reactive Changes in White Cells
121(12)
Leucocytosis
121(9)
Conclusions
130(3)
8 Leukaemias and Lymphomas
133(49)
The Nature of Leukaemia and Lymphoma
133(9)
Principles of Treatment
142(4)
Acute Lymphoblastic Leukaemia
146(5)
Acute Myeloid Leukaemia
151(7)
Chronic Myelogenous Leukaemia
158(8)
Non-Hodgkin Lymphoma
166(12)
Hodgkin Lymphoma
178(4)
Conclusions
180(2)
9 Polycythaemia, Thrombocytosis and the Myeloproliferative Neoplasms
182(19)
The Nature of the Myeloproliferative and Myelodysplastic/Myeloproliferative Neoplasms
184(1)
Polycythaemia
184(6)
Thrombocytosis
190(3)
Bone Marrow Fibrosis
193(4)
Myelodysplastic/Myeloproliferative Neoplasms
197(2)
Conclusions
199(2)
10 Multiple Myeloma
201(16)
Introduction
201(1)
Multiple Myeloma
202(11)
Monoclonal Gammopathy of Undermined Significance
213(1)
Other Conditions Associated with Paraproteinaemia
214(2)
Conclusions
216(1)
11 Platelets, Coagulation and Haemostasis
217(28)
Overview of Haemostasis
217(5)
In Vitro Coagulation
222(1)
Limitation of Coagulation and Fibrinolysis
222(2)
Assessment of Coagulation Status
224(6)
Inherited Coagulation Defects
230(3)
Acquired Defects of Coagulation
233(4)
Thtombocytopenia
237(5)
Detective Platelet Function
242(1)
Conclusions
243(2)
12 Huombosis and its Management---Anticoagulant, Antiplatelet and Thrombolytic Therapy
245(18)
Haemostasis and Thrombosis
245(3)
Thtombophilia
248(2)
The Need for Anticoagulant and Antiplatelet Therapy
250(1)
Non Pharmacological Maeans of Reducing Venous Thrombocmbolism
250(1)
Patenteral Anticoagulants
251(6)
Antiplatelet Agents
257(3)
Antutothrombotic Management of Specific Conditions
260(2)
Conclusions
262(1)
13 Blood Transfusion and Haemopoietic Stem Cell Transplantation
263(24)
Blood, Blood Products and Blood Components for Transfusion
263(4)
Recuruitment, Screening and Testing of Blood Donors
267(1)
Major Blood Group Systems
267(7)
Lests Done in a Blood Transfusion Laboratory
274(2)
The Indications for Blood Transfusion
276(4)
The Adverse Effects of Transfusion
280(1)
How Blood Transfusion Can Be Made Safer
281(1)
Home Marrow and Other Haemopoietic Stem Cell Hansplantation
282(3)
Conclusions
285(2)
14 Hungs You Have to Know Before You Graduate
287(7)
How to Take a Clinical History
288(1)
How to Perform a Physical Examination
289(1)
How to Request Laboratory Tests
290(1)
How to Interpret Laboratory Tests
290(1)
How to Prescribe Blood Components
291(1)
How to Prescribe and Monitor Anticoagulant Therapy
291(1)
When to Suspect a Haematological Disorder and How to Recognise a Haematological Emergency
291(1)
How to Acquire Information You Do Not Have
292(1)
How to Relate to a Patient
293(1)
Conclusions
293(1)
15 Further Reading
294(7)
General
294(7)
1 Physiology of the Blood and Bone Marrow
295(1)
2 The Blood Count and Film
295(1)
3 Microcytic Anaemias and the Thalassaemias
295(1)
4 Macrocytic Anaemias
295(1)
5 Haemoglobinopathies and Haemolytic Anaemias
296(1)
6 Miscellaneous Anaemias, Pancytopenia and the Myelodysplastic Syndromes
297(1)
7 Leucocytosis, Leucopenia and Reactive Changes in White Cells
297(1)
8 Leukaemias and Lymphomas
297(1)
9 Polycythaemia, Thrombocytosis and the Myeloproliferative Neoplasms
298(1)
10 Multiple Myeloma
298(1)
11 Platelets, Coagulation and Haemostasis
299(1)
12 Thrombosis and Its Management---Anticoagulant, Antiplatelet and Thrombolytic Therapy
299(1)
13 Blood Transfusion and Stem Cell Transplantation
300(1)
14 Things You Have to Know Before You Graduate
300(1)
16 Preparing for Examinations and Self-Assessment
301(22)
Preparing for Exams
301(1)
Self-Evaluation Questions
302(1)
Basic Multiple Choice Questions
302(5)
Single Best Answer Multiple Choice Quetions
307(4)
Extended Matching Questions
311(7)
Answers to Questions
318(1)
Basic Multiple Choice Questions
318(2)
Single Best Answer Multiple Choice Questions
320(2)
Extended Matching Questions
322(1)
17 Answers to Test Cases
323(6)
Test Case 3.1
323(1)
Test Case 4.1
323(1)
Test Case 5.1
324(1)
Test Case 5.2
324(1)
Test Case 6.1
325(1)
Test Case 7.1
325(1)
Test Case 7.2
325(1)
Test Case 8.1
325(1)
Test Case 8.2
326(1)
Test Case 9.1
326(1)
Test Case 10.1
327(1)
Test Case 11.1
327(1)
Test Case 11.2
327(1)
Test Case 12.1
327(1)
Test Case 13.1
328(1)
Index 329