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Haematology [Minkštas viršelis]

4.25/5 (29 ratings by Goodreads)
  • Formatas: Paperback / softback, 672 pages, weight: 1448 g, 150 colour
  • Išleidimo metai: 19-Aug-2010
  • Leidėjas: Oxford University Press
  • ISBN-10: 0199568839
  • ISBN-13: 9780199568833
Kitos knygos pagal šią temą:
  • Formatas: Paperback / softback, 672 pages, weight: 1448 g, 150 colour
  • Išleidimo metai: 19-Aug-2010
  • Leidėjas: Oxford University Press
  • ISBN-10: 0199568839
  • ISBN-13: 9780199568833
Kitos knygos pagal šią temą:
Haematology provides a broad-ranging overview of the study of blood, the dynamic fluid that interfaces with all organs and tissues to mediate essential transport and regulatory functions. Written with the needs of the biomedical scientist centre-stage, it provides a firm grounding in the physiology of blood, and the key pathophysiological states that can arise. It demonstrates throughout how an understanding of the physiology underpins the key investigations carried out by a biomedical scientist to forgea clear link between science and practice. The Online Resource Centre to accompany Haematology features: For registered adopters of the book:Figures from the book, available to downloadFor students:An interactive Digital Microscope, encouraging the exploration of tissue samplesSelf-assessment modules to help you to check and reinforce understanding of the basic science introduced in each volumeVideo podcasts including interviews with practicing biomedical scientists, and 'in the lab' footage showing biomedical science in practice"--Provided by publisher.

Biomedical scientists are the foundation of modern healthcare, from cancer screening to diagnosing HIV, from blood transfusion for surgery to food poisoning and infection control. Without biomedical scientists, the diagnosis of disease, the evaluation of the effectiveness of treatment, and research into the causes and cures of disease would not be possible.

The Fundamentals of Biomedical Science series is written to reflect the challenges of practicing biomedical science today. It draws together essential basic science with insights into laboratory practice to show how an understanding of the biology of disease is coupled to the analytical approaches that lead to diagnosis.

Assuming only a minimum of prior knowledge, the series reviews the full range of disciplines to which a Biomedical Scientist may be exposed - from microbiology to cytopathology to transfusion science. Alongside volumes exploring specific biomedical themes and related laboratory diagnosis, an overarching Biomedical Science Practice volume gives a grounding in the professional and experimental skills with which any Biomedical Scientist must be equipped.

The series
DT Understands the complex roles of Biomedical Scientists in the modern practice of medicine.
DT Understands the development needs of employers and the Profession.
DT Addresses the need for understanding of a range of fundamental sciences in the context of Biomedicine.
DT Places the theoretical aspects of Biomedical Science in their practical context.

Haematology provides a broad-ranging overview of the study of blood, the dynamic fluid that interfaces with all organs and tissues to mediate essential transport and regulatory functions.

Written with the needs of the biomedical scientist centre-stage, it provides a firm grounding in the physiology of blood, and the key pathophysiological states that can arise. It demonstrates throughout how an understanding of the physiology underpins the key investigations carried out by a biomedical scientist to forge a clear link between science and practice.

Online Resource Centre
The Online Resource Centre to accompany Haematology features:

For registered adopters of the book:
DT Figures from the book, available to download

For students:
DT An interactive Digital Microscope, encouraging the exploration of tissue samples
DT Self-assessment modules to help you to check and reinforce understanding of the basic science introduced in each volume
DT Video podcasts including interviews with practicing biomedical scientists, and 'in the lab' footage showing biomedical science in practice

Recenzijos

A very good resource. Chapters are very well elaborated with latest up to date in depth information. Inclusion of learning objectives, summaries and in particular key terms and key points gives it advantage over many other texts currently available. Indu Singh, School of Medical Sciences, RMIT University Covers a range of haematological topics that are both up to date and very comprehensive. Gordon Lowe, School of Pharmacy and Biomolecular Scienes, Liverpool John Moores University Laboratory aspects of haematology comprises about 50% of FRCPath exams. I feel that this book is indispensible for passing laboratory aspects in FRCPath exams, both written and oral. The diagrams and writing style are very clear and easy to understand. I highly recommend this book to the future trainees. Dr Yogesh Jethava, Specialist Registrar in Haematology, Guy's & St Thomas' Hospital

An introduction to the Fundamentals of Biomedical Science series vii
Contributors xi
Table 1 Reference Ranges
xiii
Abbreviations xv
1 Haematology and Haemopoiesis
1(68)
1 Introduction to haematology
3(14)
1.1 What is haematology?
3(1)
1.2 A classification of haematology
4(2)
1.3 The role of the biomedical scientist in the haematology laboratory
6(2)
1.4 Additional roles of biomedical scientists
8(2)
1.5 The role of haematology in the provision of healthcare
10(2)
1.6 The overlap with other pathology disciplines
12(2)
1.7 The role of the professional body
14(3)
2 Major haematology parameters and basic techniques
17(31)
2.1 Obtaining a blood sample
17(1)
2.2 Anticoagulants
18(2)
2.3 Major techniques
20(5)
2.4 The blood film
25(2)
2.5 The full blood count
27(8)
2.6 Rheology
35(2)
2.7 Haemostasis
37(6)
2.8 Haematinics
43(2)
2.9 The reference range
45(3)
3 Haemopoiesis and the bone marrow
48(21)
3.1 Overview of the cellular constituents of the blood
48(1)
3.2 Ontogeny of haemopoiesis
49(1)
3.3 Bone marrow architecture and cellularity
50(1)
3.4 Models of differentiation, stem cells, and growth factors
50(5)
3.5 Specific lineage haemopoiesis
55(7)
3.6 Bone marrow sampling and analysis
62(7)
2 Peripheral Blood Cells in Health and Disease
69(192)
4 The physiology of the red blood cell
71(33)
4.1 The development of the red blood cell: erythropoiesis
72(5)
4.2 The red blood cell membrane
77(5)
4.3 The cytoplasm of the red blood cell
82(14)
4.4 The death of the red cell
96(2)
4.5 The red blood cell under the microscope
98(6)
5 The pathology of the red blood cell: Part 1
104(39)
5.1 Diseases of the red blood cell
104(4)
5.2 Anaemia arising from changes in the bone marrow
108(5)
5.3 Iron-related disease
113(13)
5.4 Anaemia arising from lack of vitamins
126(10)
5.5 Anaemia of chronic disease (ACD)
136(7)
6 The pathology of the red blood cell: Part 2
143(47)
6.1 Immune-mediated and other `extrinsic' causes of haemolytic anaemia
144(10)
6.2 Haemoglobinopathy
154(23)
6.3 Membrane and enzyme defects
177(7)
6.4 Erythrocytosis and polycythaemia
184(6)
7 Blood-borne parasites
190(36)
7.1 Introduction
190(1)
7.2 Malaria
191(21)
7.3 Babesiosis
212(2)
7.4 Trypanosomiasis
214(3)
7.5 Leishmaniasis
217(2)
7.6 Filariasis
219(7)
8 White blood cells in health and disease
226(35)
8.1 Introduction
227(1)
8.2 Granulocytes
227(15)
8.3 Monocytes
242(2)
8.4 Lymphocytes
244(11)
8.5 Light microscopy
255(6)
3 Haematological Malignancies
261(172)
9 An introduction to haematological malignancies
263(41)
9.1 A background to haematological malignancies
264(5)
9.2 Signal transduction
269(1)
9.3 An introduction to the cell cycle
270(6)
9.4 Chromosomes and nomenclature
276(3)
9.5 An introduction to genetic mutation
279(10)
9.6 Epigenetics
289(2)
9.7 Clonality
291(4)
9.8 Mechanisms of oncogenesis
295(1)
9.9 Inheritance and leukaemia
296(2)
9.10 Environmental causes of haematological malignancies
298(6)
10 The laboratory investigation of haematological malignancies
304(37)
10.1 Patient presentation
305(2)
10.2 The full blood count
307(2)
10.3 Blood film
309(3)
10.4 Bone marrow assessment
312(8)
10.5 Cytochemistry
320(3)
10.6 Immunophenotyping
323(8)
10.7 Cytogenetic analysis
331(6)
10.8 Molecular techniques
337(4)
11 An introduction to classification systems: myeloid neoplasms
341(40)
11.1 Why is classification important?
342(1)
11.2 The main classification systems
342(19)
11.3 Myelodysplastic syndrome
361(8)
11.4 Myelodysplastic/myeloproliferative diseases
369(2)
11.5 Myeloproliferative neoplasms
371(10)
12 An introduction to classification systems: lymphoid neoplasms
381(52)
12.1 The history of lymphoid classification
382(9)
12.2 Acute lymphoblastic leukaemias (ALL)
391(4)
12.3 Precursor lymphoid neoplasms
395(3)
12.4 Mature B-cell neoplasms
398(26)
12.5 Mature T-cell and NK-cell neoplasms
424(4)
12.6 Hodgkin lymphoma
428(5)
4 Haemostasis in Health and Disease
433(180)
13 Normal haemostasis
435(42)
13.1 Introduction to haemostasis
435(1)
13.2 Primary haemostasis
436(13)
13.3 Secondary haemostasis
449(19)
13.4 Fibrinolysis
468(9)
14 Bleeding disorders and their laboratory investigation
477(51)
14.1 Bleeding disorders
477(3)
14.2 Von Willebrand's disease
480(2)
14.3 Laboratory investigation of a suspected bleeding disorder
482(26)
14.4 Diagnosis of platelet disorders
508(20)
15 Thrombophilia
528(38)
15.1 Introduction
528(1)
15.2 Natural anticoagulants
529(12)
15.3 Antiphospholipid antibodies
541(19)
15.4 Thrombosis
560(6)
16 Haemostasis and anticoagulation
566(47)
16.1 Reasons for anticoagulation therapy
566(6)
16.2 Current therapeutic anticoagulant pharmaceuticals for VTE
572(10)
16.3 Current therapeutic anticoagulant pharmaceuticals for arterial thrombosis
582(2)
16.4 Laboratory monitoring of anticoagulant therapy
584(19)
16.5 Management of oral anticoagulant therapy
603(10)
Glossary 613(17)
References 630(1)
Index 631
Dr Andrew Blann is Honorary Senior Lecturer in Medicine and Consultant Clinical Scientist in the University Department of Medicine, Sandwell and West Birmingham Hospitals NHS Trust and a visiting lecturer in the Department of Biomedical Science, University of Wolverhampton. A Deputy Chief Examiner in Haematology at the Institute of Biomedical Science, Andrew has edited several books, and is author of Routine Blood Results Explained (M & K Updates, 2006). Dr Gavin Knight is Senior Lecturer in the Department of Biomedical Science and Pharmacy at the University of Portsmouth, where he teaches haematology at intermediate and advanced undergraduate level, and MSc level. His research explores primary and secondary central nervous system lymphomas. Dr Gary Moore is Consultant Biomedical Scientist in the Haemostasis Laboratories of the Centre for Haemostasis & Thrombosis, Guy's & St. Thomas' NHS Foundation Trust. Gary is a visiting lecturer at the University of Portsmouth. He has been a member of the IBMS Haematology Scientific Advisory Panel since early 2002, and has been IBMS Chief Examiner in Haematology since mid 2005 having been Deputy Chief Examiner from early 2004.