Preface. By The Editors ix Part I. Stem Cell Biology In Vitro Introduction to Stem Cell Biology In Vitro: Threshold to the Future 1(8) C. Eaves C. Miller E. Conneally J. Audet R. Oostendorp J. Cashman P. Zandstra S. Rose-John J. Piret A. Eaves Hematopoietic Commitment during Embryogensis 9(8) Scott Robertson Marion Kennedy Gordon Keller Humoral Regulation of Hematopoietic Stem Cells 17(8) Makio Ogawa Takuya Matsunaga Expression of Novel Surface Antigens on Early Hematopoietic Cells 25(15) Hans-Jorg Buhring Martina Seiffert Thomas A. Bock Stefan Scheding Andreas Thiel Alexander Scheffold Lothar Kanz Wolfram Brugger Part II. Stem Cell Biology In Vivo Lymphohematopoietic Stem Cell Engraftment 40(8) Peter J. Quesenberry F. Marc Stewart Suju Zhong Houri Habibian Christina McAuliffe Judy Reilly Jane Carlson Mark Dooner Susie Nilsson Stefan Peters Gary Stein Janet Stein Rob Emmons Brian Benoit Ivan Bertoncello Pamela Becker Homing of Long-Term and Short-Term Engrafting Cells In Vivo 48(9) Sophie M. Lanzkron Michael I. Collector Saul J. Sharkis Further Characterization of CD34-Low/Negative Mouse Hematopoietic Stem Cells 57(14) Hiromitsu Nakauchi Hina Takano Hideo Ema Masatake Osawa Biology of IL-8-Induced Stem Cell Mobilization 71(12) Willem E. Fibbe Johannes F. M. Pruijt Gerjo A. Velders Ghislain Opdenakker Yvette Van Kooyk Carl G. Figdor Roel Willemze (R)Evolutionary Considerations in Hematopoietic Development 83(11) Donna D. Cooper Gerald J. Spangrude Part III. Gene Transfer into Hematopoietic Stem Cells Stem Cell Gene Therapy for the β-Chain Hemoglobinopathies: Problems and Progress 94(15) David W. Emery George Stamatoyannopoulos Retroviral-Fibronectin Interactions in Transduction of Mammalian Cells 109(6) David A. Williams Amphotropic Retrovirus Transduction of Hematopoietic Stem Cells 115(10) Donald Orlic Laurie J. Girard Stacie M. Anderson Stephane Barrette Hal E. Broxmeyer David M. Bodine Effects of Retroviral-Mediated MDR1 Expression on Hematopoietic Stem Cell Self-Renewal and Differentiation in Culture 125(17) Kevin D. Bunting Jacques Galipeau David Topham Ely Benaim Brian P. Sorrentino Part IV. Hematopoietic Microenvironment Effects of CC, CXC, C, and CX3C Chemokines on Proliferation of Myeloid Progenitor Cells, and Insights into SDF-1-Induced Chemotaxis of Progenitors 142(22) Hal E. Broxmeyer Chang H. Kim Scott H. Cooper Giao Hangoc Robert Hromas Louis M. Pelus Dissecting the Marrow Microenvironment 164(7) Beverly Torok-Storb Mineo Iwata Lynn Graf Joann Gianotti Heidi Horton Michael C. Byrne Stromal Inhibition of Myeloid Differentiation: A Possible Role for hJaggedl 171(5) Junji Tanaka Mineo Iwata Lynn Graf Ian Guest Beverly Torok-Storb Regulation of Transendothelial Migration of Hematopoietic Progenitor Cells 176(11) Robert Mohle Frank Bautz Shahin Rafii Malcolm A. S. Moore Wolfram Brugger Lothar Kanz Hematopoietic Stem/Progenitor Cell Mobilization: A Continuing Quest for Etiologic Mechanisms 187(13) Thalia Papayannopoulou Part V. Animal Models for Hematopoietic Stem Cells Characterization of Purified and Ex Vivo Manipulated Human Hematopoietic Progenitor and Stem Cells in Xenograft Recipients 200(11) Thomas A. Bock Benedikt L. Ziegler Hans-Jorg Buhring Stefan Scheding Wolfram Brugger Lothar Kanz Absence of CD34 on Some Human SCID-Repopulating Cells 211(9) John E. Dick Engraftment and Multilineage Expression of Human Bone Marrow CD34- Cells In Vivo 220(13) Esmail D. Zanjani Graca Almeida-Porada Anne G. Livingston Christopher D. Porada Makio Ogawa Ex Vivo Expansion and Genetic Marking of Primitive Human and Baboon Hematopoietic Cells 233(10) Jeffrey A. Medin John E. Brandt Elen Rozler Mary Nelson Amelia Bartholomew Congfen Li Julius Turian John Chute Theodore Chung Ronald Hoffman Part VI. Molecular Biology of Hematopoietic Stem Cells Isolation of Stem Cell-Specific cDNAs from Hematopoietic Stem Cell Populations 243(13) Donald Orlic Shari L. Laprise Amanda P. Cline Stacie M. Anderson David M. Bodine Embryonic Beginnings of Definitive Hematopoietic Stem Cells 256(9) Elaine Dzierzak Asymmetric Cell Divisions in Hematopoietic Stem Cells 265(9) Tim H. Brummendorf Wieslawa Dragowska Peter M. Lansdorp Searching for Stem Cell Regulatory Molecules: Some General Thoughts and Possible Approaches 274(15) Ihor Lemischka Part VII. Controls of Early Hematopoiesis Stem Cells, Pre-Progenitor Cells and Lineage-Committed Cells: Are Our Dogmas Correct? 289(16) D. Metcalf Signaling Domains of the βc Chain of the GM-CSF/IL-3/IL-5 Receptor 305(9) Keiko Okuda Rosemary Foster James D. Griffin Thrombopoietin and Hematopoietic Stem Cell Development 314(6) Kenneth Kaushansky G-CSF Receptor Mutations in Patients with Severe Congenital Neutropenia Do Not Abrogate Jak2 Activation and Stat1/Stat3 Translocation 320(8) A. Herbst M. Koester D. Wirth H. Hauser K. Welte Part VIII. Clinical Appraoches The Placental/Umbilical Cord Blood Program of the New York Blood Center: A Progress Report 328(8) Pablo Rubinstein John W. Adamson Cladd Stevens The Role of Megadose CD34+ Progenitor Cells in the Treatment of Leukemia Patients without a Matched Donor and in Tolerance Induction for Organ Transplantation 336(15) Yair Reisner Esther Bachar-Lustig Hong-Wei Li Franco Aversa Andrea Velardi Massimo F. Martelli Transplantation of Megadoses of Purified Haploidentical Stem Cells 351(12) R. Handgretinger M. Schumm P. Lang J. Greil A. Reiter P. Bader D. Niethammer T. Klingebiel Approaches to Dendritic Cell-Based Immunotherapy after Peripheral Blood Stem Cell Transplantation 363(9) W. Brugger P. Brossart S. Scheding G. Stuhler K. Heinrich V. Reichardt F. Grunebach H.-J. Buhring L. Kanz Mixed Hematopoietic Chimerism after Marrow Allografts: Transplantation in the Ambulatory Care Setting 372(5) Rainer Storb Cong Yu Brenda M. Sandmaier Peter A. McSweeney George Georges Richard A. Nash Ann Woolfrey Clinical Applications of Mixed Chimerism 377(10) Beate G. Exner Michele A. Domenick Marianne Bergheim Yvonne M. Mueller Suzanne T. Ildstad Poster Papers Canine Lymphocyte Expression of Retrovirally Transferred Human Common Gamma Chain 387(4) Todd Whitwam Mark E. Haskins Paula S. Henthorn David M. Bodine Jennifer M. Puck Effects of Several Cytokine Combinations on Retrovirus-Mediated Human MDR1 Gene Transfer into Bone Marrow Hematopoietic Cells 391(4) S. Zhou Y. Tong P. H. Tang N. Mao Thrombopoietin and Interleukin-3 Are Chemotactic and Chemokinetic Chemoattractants for a Factor-Dependent Hematopoietic Progenitor Cell Line 395(4) Chang H. Kim Hal E. Broxmeyer A Human Factor-Dependent Cell Line Simulates Cobblestone Formation under Human Bone Marrow Stromal Cells In Vitro 399(4) Charlie R. Mantel Alessandra Balduini Hal E. Broxmeyer Index of Contributors 403
