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Handbook of Medicinal Chemistry: Principles and Practice 2nd edition [Kietas viršelis]

Edited by (Cardiff University, UK), Edited by (AstraZeneca, Sweden)
  • Formatas: Hardback, 1050 pages, aukštis x plotis: 246x189 mm, weight: 2191 g, No
  • Išleidimo metai: 03-Feb-2023
  • Leidėjas: Royal Society of Chemistry
  • ISBN-10: 1788018982
  • ISBN-13: 9781788018982
Kitos knygos pagal šią temą:
Handbook of Medicinal Chemistry: Principles and Practice 2nd editionDidesnis paveikslėlis
  • Formatas: Hardback, 1050 pages, aukštis x plotis: 246x189 mm, weight: 2191 g, No
  • Išleidimo metai: 03-Feb-2023
  • Leidėjas: Royal Society of Chemistry
  • ISBN-10: 1788018982
  • ISBN-13: 9781788018982
Kitos knygos pagal šią temą:
Pastovi nuoroda: https://www.kriso.lt/db/9781788018982.html
Raktažodžiai:
The 2nd edition of The Handbook of Medicinal Chemistry is a carefully curated compilation of writing from global experts. Using their broad experience of medicinal chemistry, project leadership and drug discovery from both industry, academic and charity perspectives they are able to provide unparalleled insight into the field in a single, invaluable volume.

Completely revised and updated, the 2nd edition of The Handbook of Medicinal Chemistry draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies.

This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field.

Physicochemical Properties;

Synthesis in Medicinal Chemistry;

Useful Computational Chemistry Tools for Medicinal Chemistry;

Structure-based Design for Medicinal Chemists;

Fragment-based Ligand Discovery;

Machine Learning in Drug Design;

Drug Metabolism;

ADME Optimization in Drug Discovery;

Molecular Biology for Medicinal Chemists;

Assays;

In Vitro Biology: Measuring Pharmacological Activity That Will Translate to
Clinical Efficacy;

Animal Models: Practical Use and Considerations;

Bioinformatics for Medicinal Chemistry;

Translational Science;

Discovery Toxicology in Lead Optimization;

Toxicology and Drug Development;

Patents for Medicines;

Target Validation for Medicinal Chemists;

Lead Optimisation: What you should know!;

Pharmaceutical Properties The Importance of Solid Form Selection;

The Medicinal Chemistry and Process Chemistry Interface;

Clinical Drug Development;

SMN2 Splicing Modification by Small Molecules A Blueprint to Tackle the
Underlying Genetic Cause of Many Underserved Diseases;

The Discovery of Checkpoint Kinase 1 Inhibitors: From Fragments to Clinical
Candidate;

Medicinal Chemistry for Neglected Diseases Malaria, Tuberculosis, Sleeping
Sickness, Leishmaniasis and River Blindness;

New Therapeutic Chemical Modalities: Compositions, Modes-of-action, and Drug
Discovery