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Handbook of Reagents for Organic Synthesis: Reagents for Heteroarene Functionalization [Kietas viršelis]

Edited by (University de Montreal)
  • Formatas: Hardback, 824 pages, aukštis x plotis x storis: 286x224x42 mm, weight: 2495 g
  • Išleidimo metai: 18-Sep-2015
  • Leidėjas: John Wiley & Sons Inc
  • ISBN-10: 1118726596
  • ISBN-13: 9781118726594
Kitos knygos pagal šią temą:
  • Formatas: Hardback, 824 pages, aukštis x plotis x storis: 286x224x42 mm, weight: 2495 g
  • Išleidimo metai: 18-Sep-2015
  • Leidėjas: John Wiley & Sons Inc
  • ISBN-10: 1118726596
  • ISBN-13: 9781118726594
Kitos knygos pagal šią temą:

Heteroarenes are among the most prevalent structural units in natural products, pharmaceuticals, agrochemicals, and other compounds of scientific or commercial interest. In the last decade, a broad range of novel synthetic methods has been developed to not only facilitate construction of the heteroarene motif, but to enable its modification through direct C H functionalization. This Handbook describes 117 key reagents for selective heteroarene functionalization reactions, including both traditional and transition metal-catalyzed C H functionalization. Since these reactions typically involve one heteroarene, a coupling partner and a catalyst, the handbook not only focuses on the catalyst itself but also contains other key reaction species.

All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 117 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.

Preface ix
Introduction xi
Recent Review Articles and Monographs xiii
Short Note on InChIs and InChIKeys xv
Acetic Anhydride
1(7)
Acetyl Chloride
8(10)
Aluminum Chloride
18(7)
Aluminum Trifluoromethanesulfonate
25(4)
Antimony Trifluoromethanesulfonate
29(2)
Bathophenanthroline
31(3)
1,2-Benzodiazine
34(1)
Benzopyrazole
35(4)
Benzotriazole
39(3)
Bis(allyl)di-/μ-chlorodipalladium
42(24)
Bis(benzonitrile)dichloropalladium(II)
66(26)
Bis(dibenzylideneacetone)palladium(0)
92(15)
B is(1,10-phenanthroline)palladium
Hexaliuorophosphate
107(2)
Bis[ tris(1,1-dimcthylethyl)-phosphine]palladium
109(3)
Bromine
112(5)
N'-Bromosuccinimide
117(10)
n-Butyllithium
127(16)
Sec-Butyllithium
143(12)
tert-Butyllithium
155(9)
Butyllithium--Potassium tert-Butoxide
164(9)
Cesium Acetate
173(2)
N-Chlorosuccinimide
175(9)
Copper(II) Acetate
184(7)
Copper(II) Bromide
191(6)
Copper(I) Chloride
197(14)
Copper(II) Chloride
211(8)
Copper(I) Iodide
219(10)
Copper(II) Trifluoroacetate
229(1)
Copper(II) Trifluoromethanesulfonate
230(7)
N-Cyano-4-methyl-N-phenylbenzenesulfonamide
237(4)
Dibenzofuran
241(2)
Dibenzothiophene
243(4)
1,1 -Di-tert-butyl Peroxide
247(5)
Di-tert-butyl(methyl)phosphine
252(6)
Di-test-butyl(methyl)phosphonium Tetrafluoroborate
258(6)
Dichlorobis(acetonitrile) Palladium
264(16)
Dichlorobis(triphenylphosphine)palladium(II)
280(11)
Di-μ-chlorotetrakis[ (1,2-η)-cyclooctene]diiridium
291(1)
Di-μ-methoxobis(1,5-cyclooctadiene)diiridium(I)
292(4)
Dimethyl Diazomalonate
296(10)
(2S',5,S')-2-(1,1-Dimethylethyl)-3-methyl-5-(phenylmethyl)-4-imidazolidinone
306(4)
Diphenyliodonium Hexafluorophosphate
310(2)
Diphenyliodonium Triflate
312(3)
Dysprosium Trifluoromethanesulfonate
315(4)
A'-fluoro-N-(phenylsulfonyl)benzenesulfonamide
319(11)
1- Fluoro-2,4,6-trimclhylpyridinium Tetrafluoroborate
330(4)
Furan
334(5)
Gallium(III) Trifluoromethanesulfonate (Gallium Triflate)
339(4)
Hafnium(IV) Trifluoromethanesulfonate
343(6)
Hypofluorous acid--acetonitrile complex
349(6)
Indium(III) Triflate
355(6)
Indolizine
361(2)
Iron, Bis(pyridine)bis(2-pyridinecarboxylato-N1,O2)
363(3)
Isoindole
366(1)
Isoquinoline
367(4)
Lithium t-Butoxide
371(2)
Lithium Dichloro(1-metliylethyl)-magnesate
373(2)
Lithium Dichloro(22,6,6-telramethylpiperidinato)-zincate
375(4)
Magnesium tert-butoxide
379(1)
Manganese(III) Acetate
380(9)
4-Methoxypyridine N-oxide
389(3)
6-Methoxyquinoline-N-oxide
392(3)
2- Methylbenzothiazole
395(3)
N-Methylimidazole
398(13)
N-Methylindole
411(3)
1-[ [ (4-Methylphenyl)sulfonyl]amino]-pyridinium inner salt
414(1)
Methyltrioxorhenium
415(12)
Nitric Acid
427(8)
4,4,4',4',5,5,5',5'-Octamethyl-2,2'-bi-1,3,2-dioxaborolane
435(12)
1,2,5-Oxadiazole
447(1)
Oxalyl Chloride--Dimethylformamide
448(1)
Oxazole
449(8)
Palladium(II) Acetate
457(34)
Palladium(II) Bromide
491(8)
Palladium(Il) Chloride
499(17)
Palladium(π-cinnamyl) Chloride Dimer
516(1)
Palladium Pivalate
517(2)
Pentamethylcyclopentadienylrhodium(III) chloride dimer
519(6)
1,10-Phenanthroline
525(3)
1,10-Phenanthroline, 1-oxide
528(1)
(1,10-Phenanthroline) (trifluoromethyl) (triphenylphosphine)copper
528(1)
Pinacolborane
529(7)
Pivalic Acid
536(9)
Potassium Acetate
545(6)
Propanoic acid, 2-Diazo-, 2-methyl-1-(1-methylethyl)propyl ester
551(3)
Pyridazine
554(3)
Pyridazine N-Oxide
557(2)
Pyridine
559(7)
Pyridine N-Oxide
566(6)
Pyrrole
572(5)
Quinoline
577(4)
Ruthenium Dodecacarbonyltri Triangulo
581(4)
Scandium Trifluoromethanesulfonate
585(9)
Silver(I) Acetate
594(9)
Silver(I) Carbonate
603(9)
Silver(I) Fluoride
612(6)
Silver(I) Nitrate
618(10)
Silver(I) Oxide
628(8)
Silver(I) Trifluoromethanesulfonate
636(13)
Sulfur Trioxide-Pyridine
649(2)
Tetrakis(triphenylphosphine)palladium(0)
651(8)
1,2,4,5-Tetratzine
659(2)
1H-Tetrazole
661(1)
1.2.3-Thiadiazole
662(1)
1.2.4-Thiadiazole
663(1)
2H-2,3-Triazole
663(2)
1,2,4-Triazole
665(3)
Tri-tert-butylphosphine
668(9)
Tri-tert-butylphosphonium Tetrafluoroborate
677(9)
Tricyclohexylphosphine
686(11)
(S)-(Trifluoromethyl)diphenylsulfonium Triflate
697(4)
(Trifluoromethyl)tris(triphenylphosphine)-copper
701(2)
Tris(dibenzylideneacetone)dipalladium--Chloroform
703(6)
Tris(1,1,1,3,3,3-hexafluoro-2-propyl)phosphite
709(2)
Yttrium Trifluoromethanesulfonate
711(4)
Zinc Isopropylsulfinate
715(2)
Zinc Trifluoromethanesulfinate
717(4)
List of Contributors 721(12)
Reagent Formula Index 733(4)
Subject Index 737
André B. Charette received his B.Sc. in 1983 from the Université de Montréal. He then moved south of the border to the University of Rochester to continue his graduate studies. Under the supervision of Robert K. Boeckman Jr., he completed the total synthesis of the ionophore calcimycin, which earned him the degrees of M.Sc. (1985) and Ph.D. (1987). Following an NSERC postdoctoral fellowship at Harvard University with D. A. Evans, he began his academic career at the Université Laval (Quebec City) in 1989. In 1992, he joined the Université de Montréal, where he has been promoted to the rank of Full Professor since 1998. With a record of close to 200 publications and numerous invited lectures throughout the world, Prof. Charette has achieved worldwide recognition in his field. His research lies primarily in the development of new methods for the stereoselective synthesis of organic compounds and natural products. Among his recent honors are the CSC Alfred Bader Award (2009), the Prix Marie Victorin of the Government of Quebec (2008), and an ACS Arthur C. Cope Award (2007).