Regulatory emphasis on the effects of toxic chemicals has caused the field to rapidly expand. This reference is intended for both toxicologists and pathologists, providing basic information in each area and of the combined field and dealing systematically with organ-specific injury, including mechanisms of organ injury, cellular response, and evaluation of injury. The amount of space allocated to topics readily accessible in standard textbooks is minimal; emphasis is on mechanisms of action of various classes of toxicants and the responses of tissues to these insults. Annotation copyright Book News, Inc. Portland, Or.
This is the first comprehensive reference work on toxicologic pathology, an emerging field that integrates the mechanisms of toxic injury with the resulting pathology. Chapters deal systematically with organ-specific toxic injury, describing the mechanisms of injury, morphological expression of the injury, and evaluation of the pathology. Additional chapters introduce the field to the uninitiated and address such topics as techniques used for morphological evaluation, risk assessment, and regulatory aspects. The Handbook of Toxicologic Pathology will quickly establish itself as the classic reference work in this field for years to come.
Key Features
* Comprehensive, "user friendly" reference text on toxicologic pathology
* Large, easy-to-use 8 1/2" x 11", double-column format
* Systematic approach to each organ or system
* More than 500 illustrations and 90 tables complement the text
* Over 2,000 references for easy access to the primary literature
* Unique chapters written by leading authorities
Daugiau informacijos
Key Features * Comprehensive, user friendly reference text on toxicologic pathology * Large, easy-to-use 8 1/2 x 11, double-column format * Systematic approach to each organ or system * More than 500 illustrations and 90 tables complement the text * Over 2,000 references for easy access to the primary literature * Unique chapters written by leading authorities
Toxicologic Pathology: An Introduction. The Pathologist in Toxicologic
Testing and Evaluation. Evaluation of Altered Morphology. Quantitative
Techniques for Morphological Evaluation. Biochemical Basis of Toxicity.
Biochemical Mechanisms of Toxic Cell Injury. Chemical Carcinogenesis.
Limitations of Toxicologic Pathology. Regulatory Aspects and Potential
Pitfalls of Toxicologic Pathology. Risk Assessment. Skin and Oral Mucosa.
Gastrointestinal Tract. Pancreas. Hepatobiliary System. Urinary System. Blood
and Bone Marrow. Immune System. Skeletal System. Cardiovascular and Skeletal
Muscular Systems. Nervous System. Endocrine System. Respiratory System. Male
Reproductive System. Female Reproductive System. The Fetus. Radiation and
Heat.
Chapter References. Index.
Professor Haschek-Hock has served as president of the Society of Toxicologic Pathology and the Society of Toxicologys Comparative and Veterinary Specialty Section, as well as Councilor of the American College of Veterinary Pathologists, board member of the American Board of Toxicology; as Associate Editor for Toxicological Sciences and for Toxicologic Pathology; as Editorial Board member for Fundamental and Applied Toxicology, Veterinary Pathology and Toxicologic Pathology. She has served as a member on the USFDA Veterinary Medicine Advisory Committee for the Center for Veterinary Medicine, the EPAs FIFRA Science Advisory Panel, and National Academy of Sciences Committee. She currently serves on the Board of Directors of the C.L. Davis Foundation for the Advancement of Veterinary and Comparative Pathology. She was awarded the Society of Toxicologic Pathologys Achievement Award in 2007 and the Midwest Regional Chapter Society of Toxicologys Kenneth DuBois Award in 2011. Professor Rousseaux is a Fellow of the Royal College of Pathology, Diplomate of the American Board of Toxicology, Fellow of the Academy of Toxicological Sciences, and Fellow of the International Academy of Toxicologic Pathology. He is Professor (Adjunct) in the Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of Ottawa, Canada. He has 35 years of experience in comparative and toxicologic pathology with a research focus on herbal remedies, fetal development and teratology, and environmental pollutants. He has described, investigated, and evaluated numerous toxicologic pathology issues associated with pharmaceutical, pesticides, and agrochemicals. He has served on the editorial board of Toxicologic Pathology. He is a former president of the Society of Toxicologic Pathology
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